Results 81 to 90 of about 175,877 (209)
Towards a Mathematical Foundation of Immunology and Amino Acid Chains [PDF]
We attempt to set a mathematical foundation of immunology and amino acid chains. To measure the similarities of these chains, a kernel on strings is defined using only the sequence of the chains and a good amino acid substitution matrix (e.g. BLOSUM62). The kernel is used in learning machines to predict binding affinities of peptides to human leukocyte
arxiv
Serology and DNA techniques are employed for Human Leukocyte Antigen (HLA) typing in different transplant centers. Results may not always correlate well and may need retyping with different technique.
Hamid Nawaz Tipu+2 more
doaj
Identification of Two Novel HLA-A∗0201-Restricted CTL Epitopes Derived from MAGE-A4
MAGE-A antigens belong to cancer/testis (CT) antigens that are expressed in tumors but not in normal tissues except testis and placenta. MAGE-A antigens and their epitope peptides have been used in tumor immunotherapy trials.
Zheng-Cai Jia+7 more
doaj +1 more source
The Dual Role of HLA-C in Tolerance and Immunity at the Maternal-Fetal Interface
To establish a healthy pregnancy, maternal immune cells must tolerate fetal allo-antigens and remain competent to respond to infections both systemically and in placental tissues.
Henrieta Papúchová+6 more
doaj +1 more source
The role of HLA antigens in recurrent primary focal segmental glomerulosclerosis. [PDF]
Batal I+4 more
europepmc +1 more source
Genetic marker in juvenile diabetic retinopathy
Thirty five patients with insulin dependent diabetes mellitus (IDDM) were investigated for development of retinal microangiopathy by fluorescein angiography. HLA typing (A,B.C antigens) was done as a genetic marker. There was no statistically significant
Khosla P+4 more
doaj
A Case Report of Aggressive Fumarate Hydrase-deficient Renal Cell Carcinoma With Loss of HLA Antigens. [PDF]
Miura Y+8 more
europepmc +1 more source
Protective Allele for Multiple Sclerosis HLA-DRB1*01:01 Provides Kinetic Discrimination of Myelin and Exogenous Antigenic Peptides. [PDF]
Risk of the development of multiple sclerosis (MS) is known to be increased in individuals bearing distinct class II human leukocyte antigen (HLA) variants, whereas some of them may have a protective effect.
Bashinskaya, Vitalina+19 more
core +1 more source
Human leukocyte antigens and genetic susceptibility to lymphoma [PDF]
Familial aggregation, coupled with ethnic variation in incidence, suggests that inherited susceptibility plays a role in the development of lymphoma, and the search for genetic risk factors has highlighted the contribution of the human leukocyte antigen (
Jarrett, R.F., McAulay, K.A.
core +1 more source
Objective: Host immunogenetics (Human Leukocyte Antigen, HLA) play a critical role in the human immune response to melanoma, influencing both melanoma prevalence and immunotherapy outcomes.
Apostolos P Georgopoulos+2 more
doaj +1 more source