Results 81 to 90 of about 175,877 (209)

Towards a Mathematical Foundation of Immunology and Amino Acid Chains [PDF]

open access: yesarXiv, 2012
We attempt to set a mathematical foundation of immunology and amino acid chains. To measure the similarities of these chains, a kernel on strings is defined using only the sequence of the chains and a good amino acid substitution matrix (e.g. BLOSUM62). The kernel is used in learning machines to predict binding affinities of peptides to human leukocyte
arxiv  

Identification of HLA Class I Misreads/Dropouts Using Serological Typing, in Comparison with DNA-based Typing

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2016
Serology and DNA techniques are employed for Human Leukocyte Antigen (HLA) typing in different transplant centers. Results may not always correlate well and may need retyping with different technique.
Hamid Nawaz Tipu   +2 more
doaj  

Identification of Two Novel HLA-A∗0201-Restricted CTL Epitopes Derived from MAGE-A4

open access: yesClinical and Developmental Immunology, 2010
MAGE-A antigens belong to cancer/testis (CT) antigens that are expressed in tumors but not in normal tissues except testis and placenta. MAGE-A antigens and their epitope peptides have been used in tumor immunotherapy trials.
Zheng-Cai Jia   +7 more
doaj   +1 more source

The Dual Role of HLA-C in Tolerance and Immunity at the Maternal-Fetal Interface

open access: yesFrontiers in Immunology, 2019
To establish a healthy pregnancy, maternal immune cells must tolerate fetal allo-antigens and remain competent to respond to infections both systemically and in placental tissues.
Henrieta Papúchová   +6 more
doaj   +1 more source

The role of HLA antigens in recurrent primary focal segmental glomerulosclerosis. [PDF]

open access: yesFront Immunol, 2023
Batal I   +4 more
europepmc   +1 more source

Genetic marker in juvenile diabetic retinopathy

open access: yesIndian Journal of Ophthalmology, 1989
Thirty five patients with insulin dependent diabetes mellitus (IDDM) were investigated for development of retinal microangiopathy by fluorescein angiography. HLA typing (A,B.C antigens) was done as a genetic marker. There was no statistically significant
Khosla P   +4 more
doaj  

A Case Report of Aggressive Fumarate Hydrase-deficient Renal Cell Carcinoma With Loss of HLA Antigens. [PDF]

open access: yesCancer Diagn Progn, 2023
Miura Y   +8 more
europepmc   +1 more source

Protective Allele for Multiple Sclerosis HLA-DRB1*01:01 Provides Kinetic Discrimination of Myelin and Exogenous Antigenic Peptides. [PDF]

open access: yes, 2020
Risk of the development of multiple sclerosis (MS) is known to be increased in individuals bearing distinct class II human leukocyte antigen (HLA) variants, whereas some of them may have a protective effect.
Bashinskaya, Vitalina   +19 more
core   +1 more source

Human leukocyte antigens and genetic susceptibility to lymphoma [PDF]

open access: yes, 2015
Familial aggregation, coupled with ethnic variation in incidence, suggests that inherited susceptibility plays a role in the development of lymphoma, and the search for genetic risk factors has highlighted the contribution of the human leukocyte antigen (
Jarrett, R.F., McAulay, K.A.
core   +1 more source

Nine Human Leukocyte Antigen (HLA) Class I Alleles are Omnipotent Against 11 Antigens Expressed in Melanoma Tumors

open access: yesCancer Informatics
Objective: Host immunogenetics (Human Leukocyte Antigen, HLA) play a critical role in the human immune response to melanoma, influencing both melanoma prevalence and immunotherapy outcomes.
Apostolos P Georgopoulos   +2 more
doaj   +1 more source

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