Results 101 to 110 of about 386,968 (310)

The Role of HLA Antigens and Steroid Dose on the Course of COVID-19 of Patients After Kidney Transplantation. [PDF]

Front Med (Lausanne), 2021
Dedinská I, Skálová P, Graňák K, Vnučák M, Baltesová T, Žilinská Z, Jeseňák M.   +6 more
europepmc   +1 more source

CAR‐Engineered Cell Therapies Beyond Cancer: Reprogramming Fibrosis and Immune‐Mediated Inflammation

Advanced Science, EarlyView.
CAR‐engineered cell therapies are expanding beyond cancer toward immune resetting, pathological‐cell clearance, matrix remodeling, and microenvironmental reprogramming in autoimmune, inflammatory, and fibrotic diseases. This Review compares CAR‐T, CAR‐macrophage, and CAR‐NK platforms and proposes controllable spatiotemporal reprogramming to align ...
Peng Jun Xu, Zhou Jing Zhang, Jing Jin, Hai Yuan Xu, Ya Xin Gu, Qian Qian Yang, You Lang Zhou   +6 more
wiley   +1 more source

A polyepitope DNA vaccine targeted to Her-2/ErbB-2 elicits a broad range of human and murine CTL effectors to protect against tumor challenge.

, 2007
A cDNA vaccine (pVax1/pet-neu) was designed to encode 12 different Her-2/ErbB-2-derived, HLA-A*0201-restricted dominant and high-affinity heteroclitic cryptic epitopes.
Lemonnier, François A, A. M. Jackson, Alimandi, Maurizio, Jordan Marrocco, Cencioni, Giulia, S. Chouaib, Stephanie Graf-Dubois, Graf-Dubois, S, Chouaib, S, A. Scardino, Hüseyin Firat, Graf-Dubois, Stephanie, Steven G. Smith, K. Kosmatopoulos, Kosmatopoulos, K., Smith, SG, Antonio Scardino, Roberto Bei, Giulia Cencioni, S. G. Smith, G. Cencioni, P. Correale, François A. Lemonnier, Kosmatopoulos, Kostas, Faure, Olivier, Firat, Hüseyin, Olivier Faure, Firat, H, Lemonnier, FA, Jackson, AM, Kostas Kosmatopoulos, Chouaib, Salem, Correale, P, Andrew Michael Jackson, Cusi, MG, Maria Grazia Cusi, Alimandi, M, Correale, Pierpaolo, Bei, Roberto, M. G. Cusi, Marrocco, Jordan, S. Graf Dubois, F. A. Lemonnier, Smith, Steven G, Scardino, A, Cencioni, G, Pierpaolo Correale, Graf Dubois, S, Salem Chouaib, Faure, O, Marrocco, J, Kosmatopoulos, K, Scardino, Antonio, Cusi, Maria Grazia, J. Marrocco, Bei, R, R. Bei, Maurizio Alimandi, H. Firat, O. Faure, Jackson, Andrew Michael, MARROCCO J., FIRAT H., ALIMANDI M., LEMONNIER F. A., GRAF-DUBOIS S., BEI R., FAURE O., JACKSON A. M., CHOUAIB S., KOSMATOPOULOS K., CENCIONI G., CORREALE P., SCARDINO A., SMITH S. G., CUSI M. G.   +75 more
core   +1 more source

Single‐Cell Profiling Reveals Clonally Expanded CX3CR1+ T Cells in Anti‐NMDA Receptor Encephalitis

Advanced Science, EarlyView.
CX3CR1+ T cells are associated with peripheral and central immune alterations in anti‐NMDA receptor encephalitis (NMDAR‐E). They show potential responsiveness to GluN1 (NR1) peptides, potential interactions with peripheral B cells, clonal expansion, increased CD137/CD154 expression, and inflammatory cytokine production. Their preferential cerebrospinal
Lin Yan, Erdi Zhang, Yuwen Ma, Zirui Meng, Sisi Li, Yimeng Ren, Xiaohe Tian, Yangyi He, Giuseppe Battaglia, Dong Zhou, Yun Liao, Binwu Ying, Jinmei Li, Minjin Wang   +13 more
wiley   +1 more source

Non-responsiveness to hepatitis-B vaccination: revaccination and immunogenetic typing [PDF]

, 1988
Krämer A, Herth D, von Keyserlingk H, et al. Non-responsiveness to hepatitis-B vaccination: revaccination and immunogenetic typing. Klinische Wochenschrift.
Sommer, D., Ludwig, W. D., Hampl, Hartmut, Riecken, Ernst-Otto, Krämer, Alexander ; https://orcid.org/, Hahn, E. G., von Keyserlingk, H., Herth, D.   +7 more
core   +1 more source

HLA profile in patients with AIDS and tuberculosis

Brazilian Journal of Infectious Diseases
Studies carried out in various populations have reported an association between some HLA specificities and susceptibility to tuberculosis. We investigated the class I and class II HLA profile in Brazilian patients of various ethnic backgrounds who had ...
José Fernando de Castro Figueiredo, Maria de Lourdes Veronese Rodrigues, Neifi Hassam Saloum Deghaide, Eduardo Antonio Donadi   +3 more
doaj   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source

A gyermekkori 1-es típusú diabétesz genetikai és humorális immunológiai hátterének vizsgálata = Genetic and humoral immunologic determinants of childhood-onset type 1 diabetes [PDF]

, 2007
Az OTKA pályázat munkatervében kitűzött célok megvalósultak. A program az elmúlt három év alatt országos diabetes genetikai projektté nőtte ki magát (HUN-T1D-GENES program; www.diabet.hu/ diabetesgenetics).
Hermann, Róbert, Soltész, Gyula
core   +1 more source

Trypanosoma cruzi vaccine candidate antigens Tc24 and TSA-1 recall memory immune response associated with HLA-A and -B supertypes in Chagasic chronic patients from Mexico.

PLoS Neglected Tropical Diseases, 2018
Trypanosoma cruzi antigens TSA-1 and Tc24 have shown promise as vaccine candidates in animal studies. We evaluated here the recall immune response these antigens induce in Chagasic patients, as a first step to test their immunogenicity in humans.
Liliana E Villanueva-Lizama, Julio V Cruz-Chan, Amarú Del C Aguilar-Cetina, Luis F Herrera-Sanchez, Jose M Rodriguez-Perez, Miguel E Rosado-Vallado, Maria J Ramirez-Sierra, Jaime Ortega-Lopez, Kathryn Jones, Peter Hotez, Maria Elena Bottazzi, Eric Dumonteil   +11 more
doaj   +1 more source

HLA typing in Taiwanese patients with oral squamous cell carcinoma

Journal of Dental Sciences, 2014
Background/purpose: The human leukocyte antigen (HLA) system, which plays a vital role in immunity, is the most polymorphic gene complex found in the human genome. This study investigated HLA-related alleles and haplotypes in Taiwanese patients with oral
Chia-Chun Lu, Tréjaut John, Chieh-Yuan Cheng, Chu-Sheng Lin, Chung-Ji Liu   +4 more
doaj   +1 more source