Results 131 to 140 of about 25,975 (254)

Clinical features and HLA typing of immune checkpoint inhibitor-associated myasthenia gravis, myocarditis and myositis. [PDF]

Front Oncol
Lin X, Liu P, Jin M, Qi G.
europepmc   +1 more source

HLA typing by double ARMS

The Lancet, 1991
Lo, Y, Mehal, W, Wordsworth, B, Chapman, R, Fleming, K, Bell, J, Wainscoat, J   +6 more
openaire   +2 more sources

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Evaluating the Antigen and Eplet Accuracy of DQA1 Imputations With the HaploSFHI Two-Field HLA Typing Inference Tool. [PDF]

HLA
Lhotte R, Murphey C, Tafulo S, Turner D, Usureau C, Devriese M, SFHI Consortium, Letort V, Taupin JL.   +8 more
europepmc   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Ancient DNA HLA typing reveals significant shifts in frequency in Europe since the Neolithic. [PDF]

Sci Rep
Plascencia AG, Jakobsson M, Sánchez-Quinto F.   +2 more
europepmc   +1 more source

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

Hydroxychloroquine-induced acute generalized exanthematous pustulosis with HLA-typing. [PDF]

Pharmacogenomics
Zheng Q, Jin N, Cheng H.
europepmc   +1 more source

The Value of HLA Typing in Severe Cutaneous Drug Reactions. [PDF]

Indian J Dermatol, 2020
Khan S, Ghosh B.
europepmc   +1 more source

Human Leukocyte Antigen (HLA) Typing Study Identifies Maternal DQ2 Susceptibility Alleles among Infertile Women: Potential Associations with Autoimmunity and Micronutrients. [PDF]

Nutrients, 2021
Triggianese P, Perricone C, De Martino E, D'Antonio A, Chimenti MS, Conigliaro P, Ferrigno S, Giambini I, Greco E, De Carolis C.   +9 more
europepmc   +1 more source