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Baicalin-geniposide attenuates pulmonary inflammation and vascular injury via HMGB1 blockade: insights from a cerebral ischemia-reperfusion model and implications for pulmonary hypertension. [PDF]
Gao L, Wu Q, Li X, Long Y, Li N.
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HMGB1-mediated enhancement of glycolysis activates hepatic stellate cells by inhibiting ferroptosis in alcoholic hepatic fibrosis. [PDF]
Li Y +6 more
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Serum HMGB1 and Alcohol-Related Liver Disease. [PDF]
Popiolek I +9 more
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Sex-Specific Reversal of Stress-Induced Depressogenic Behaviors by Inhibition of HMGB1, TLR4, and NF-κB Signaling. [PDF]
Bahadır-Varol A +4 more
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cGAS-STING/HMGB1-mediated senescence induced by LRRK2 accelerates cartilage degeneration in osteoarthritis. [PDF]
Zhang Y, Zhu Z, Ji P, Ming J, Zhou Y.
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The multifunctional protein HMGB1: 50 years of discovery
Nature Reviews Immunology, 2023Fifty years since the initial discovery of HMGB1 in 1973 as a structural protein of chromatin, HMGB1 is now known to regulate diverse biological processes depending on its subcellular or extracellular localization. These functions include promoting DNA damage repair in the nucleus, sensing nucleic acids and inducing innate immune responses and ...
Daolin Tang, Rui Kang
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Functional Diversity of Non-Histone Chromosomal Protein HmgB1 [PDF]
The functioning of DNA in the cell nucleus is ensured by a multitude of proteins, whose interactions with DNA as well as with other proteins lead to the formation of a complicated, organized, and quite dynamic system known as chromatin. This review is devoted to the description of properties and structure of the progenitors of the most abundant non ...
E V Chikhirzhina +2 more
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