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Serum HMGB1 and Alcohol-Related Liver Disease. [PDF]

open access: yesJ Clin Med
Popiolek I   +9 more
europepmc   +1 more source
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The multifunctional protein HMGB1: 50 years of discovery

Nature Reviews Immunology, 2023
Fifty years since the initial discovery of HMGB1 in 1973 as a structural protein of chromatin, HMGB1 is now known to regulate diverse biological processes depending on its subcellular or extracellular localization. These functions include promoting DNA damage repair in the nucleus, sensing nucleic acids and inducing innate immune responses and ...
Daolin Tang, Rui Kang
exaly   +3 more sources

Functional Diversity of Non-Histone Chromosomal Protein HmgB1 [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
The functioning of DNA in the cell nucleus is ensured by a multitude of proteins, whose interactions with DNA as well as with other proteins lead to the formation of a complicated, organized, and quite dynamic system known as chromatin. This review is devoted to the description of properties and structure of the progenitors of the most abundant non ...
E V Chikhirzhina   +2 more
exaly   +3 more sources

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