Results 51 to 60 of about 11,358 (217)

Diversity in Glycosaminoglycan Binding Amongst hMPV G Protein Lineages [PDF]

Viruses, 2012
We have previously shown that hMPV G protein (B2 lineage) interacts with cellular glycosaminoglycans (GAGs). In this study we examined subtypes A1, A2 and B1 for this interaction. GAG-dependent infectivity of available hMPV strains was demonstrated using GAG-deficient cells and heparin competition.
Adamson, Penelope, Thammawat, Sutthiwan, Muchondo, Gamaliel, Sadlon, Tania, Gordon, David   +4 more
openaire   +3 more sources

Human metapneumovirus: insights from a ten-year molecular and epidemiological analysis in Germany. [PDF]

PLoS ONE, 2014
Human metapneumovirus (HMPV) is a cause of respiratory tract illness at all ages. In this study the epidemiological and molecular diversity among patients of different ages was investigated. Between 2000-2001 and 2009-2010, HMPV was detected in 3% (138/4,
Janine Reiche, Sonja Jacobsen, Katrin Neubauer, Susi Hafemann, Andreas Nitsche, Jeanette Milde, Thorsten Wolff, Brunhilde Schweiger   +7 more
doaj   +1 more source

Whole genome characteristics of respiratory human metapneumovirus isolated in Ningxia Hui Autonomous Region

Zhongguo gonggong weisheng, 2023
ObjectiveTo analyze genetic characteristics of human metapneumovirus (hMPV) strains isolated in Ningxia Hui Autonomous Region (Ningxia) for providing relevant data to construct hMPV genome database in China.
Xinning WANG, Yanyan SU, Zhonglan WU, Min CAO, Longshan LI, Jianxin PEI, Xueping MA   +6 more
doaj   +1 more source

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

iNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng, Qianqian Wang, Jiachen Zhang, Sandra Chiu   +3 more
wiley   +1 more source

A profile of knee injuries suffered by Australian army reserve soldiers [PDF]

, 2018
Partner-switching regulatory systems (PSRSs) are utilized by many different bacteria to regulate a wide array of cellular responses, from stress response to expression of virulence factors.
Schram, Ben, Orr, Rob Marc, Pope, Rodney
core   +1 more source

Molecular assays for detection of human metapneumovirus [PDF]

, 2003
The recent description of the respiratory pathogen human metapneumovirus (hMPV) has highlighted a deficiency in current diagnostic techniques for viral agents associated with acute lower respiratory tract infections.
Mackay, Ian M., Jacob, Kevin C., Woolhouse, Daniel, Waller, Katharine, Syrmis, Melanie W., Whiley, David M., Siebert, David J., Nissen, Michael, Sloots, Theo P.   +8 more
core   +2 more sources

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

Pediatric Investigation, EarlyView.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics, China Medical Education Association, Cooperative Group of Asthma, the Subspecialty Group of Respiratory, the Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of the Chinese Non‐public Medical Institutions Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China News of Drug Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, China International Medical Foundation   +16 more
wiley   +1 more source

An Unusual Resurgence of Human Metapneumovirus in Western Australia Following the Reduction of Non-Pharmaceutical Interventions to Prevent SARS-CoV-2 Transmission

Viruses, 2022
Non-pharmaceutical interventions (NPIs) to reduce SARS-CoV-2 transmission disrupted respiratory virus seasonality. We examined the unusual return of human metapneumovirus (hMPV) in Western Australia following a period of absence in 2020. We analysed hMPV
David Anthony Foley, Chisha T. Sikazwe, Cara A. Minney-Smith, Timo Ernst, Hannah C. Moore, Mark P. Nicol, David W. Smith, Avram Levy, Christopher C. Blyth   +8 more
doaj   +1 more source

Human Metapneumovirus[Hmpv]

International Journal of Pharmaceutical Research and Applications
Since its discovery in 2001, human metapneumovirus (hMPV) has been found all over the world . A frequent respiratory pathogen particularly in infants and small children, is hMPV. The virus may provoke asthma and is linked to upper and lower respiratory tract infections.
Nandini Sutar Nandini Sutar, Sakshi More Sakshi More, Sakshi Powar Sakshi Powar, Arpita Bhatane Arpita Bhatane   +3 more
openaire   +1 more source

A novel case of autosomal recessive CARD11 loss‐of‐function underlying impaired antiviral immunity and a review of literature

Clinical &Translational Immunology, Volume 15, Issue 5, 2026.
We report on a patient homozygous for a novel autosomal recessive loss‐of‐function CARD11 variant, with susceptibility to live attenuated virus (LAV) vaccines and impaired clearance of multiple naturally acquired respiratory viral infections. Inborn errors of immunity affecting the CARD11‐BCL10‐MALT1 (CBM) complex should be considered in individuals ...
Hamish Anderson, Cecilia Verryt, Paula Keating, Thomas Saunders, Samuel Dalton, Barry D Hock, Liping Goddard, Kylie Drake, Anja Werno, John O'Donnell, Jeffrey R Stinson, Andrew L Snow, Kuang‐Chih Hsiao   +12 more
wiley   +1 more source