Results 101 to 110 of about 8,539 (162)

HNF1A-Maturity-Onset Diabetes of the Young (MODY) in a Family With a Rare Silent Variant: Clinical Challenges and Variable Expressivity. [PDF]

Cureus
Carvalho R, Moreira B, Parente S.
europepmc   +1 more source

Empagliflozin in HNF1A-MODY (MODY3): A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial. [PDF]

Diabetes Care
Maagensen H, Høyerup SO, Jensen JS, Thuesen ACB, Forman JL, Thomsen HH, Vestergaard H, Knop FK, Hansen T, Hædersdal S, Støy J, Vilsbøll T.   +11 more
europepmc   +1 more source

Defective HNF1A hinders GLI3 processing favoring duodenal versus pancreatic fate, thus leading to intestinal elongation in vivo. [PDF]

Genes Dev
Unger L, Larsen U, Legøy TA, Hossain MK, Gudmestad JH, Friestad A, Sharmine S, Njølstad PR, Ræder H, Herrera PL, Ghila L, Chera S.   +11 more
europepmc   +1 more source

Hyperglycemia Due to HNF1A-Mutation-Associated Maturity-Onset Diabetes of the Young (MODY) in a 6-Year-Old Kazakh Girl. [PDF]

Am J Case Rep
Toleuzhanova AB, Zholdybayeva E, Eslamgalieva S, Svyatova G, Akhmetollayeva A.   +4 more
europepmc   +1 more source

Long non-coding RNAs as molecular links and circulating biomarkers between type 2 diabetes and colorectal cancer: focus on shared signaling pathways, epigenetic regulation, and ubiquitination mechanisms. [PDF]

Front Mol Biosci
Wu L, Meng Q, Zhou Y.
europepmc   +1 more source

Hnf1aos1 as a Metabolic Coordinator of Hepatic Lipid Homeostasis and Feedback Control. [PDF]

Noncoding RNA
Armanios B, Jin J, Laddha AP, Nguyen LTG, Tawfik SM, Mishra N, Manautou JE, Zhong XB.   +7 more
europepmc   +1 more source

Developmental and MAPK-responsive transcription factors regulate distinct malignant cell states and associated genetic dependencies in pancreatic cancer. [PDF]

Nat Genet
Laise P, Turunen M, Curiel-Garcia A, Tomassoni L, Maurer HC, Elyada E, Schmierer B, Worley J, Kesner J, Tan X, Fernandez EC, Xue Y, Chen Y, Wong K, Wasko UN, Tagore S, Wang ALE, Ge S, Iuga AC, Griffin AT, Wong W, Manji GA, Alvarez MJ, Notta F, Tuveson DA, Olive KP, Califano A.   +26 more
europepmc   +1 more source

Long non-coding RNAs in the crosstalk between diabetes and colorectal cancer: molecular mechanisms and endocrine pathways. [PDF]

Front Mol Biosci
Zhang L, Li M.
europepmc   +1 more source

Molecular impact of a novel <i>HNF1B</i> missense variant in childhood-onset MODY5: a case report and functional study. [PDF]

Front Endocrinol (Lausanne)
Umeda C, Imagawa E, Hokazono S, Konuma T, Tsunogai T, Hirano D, Oishi K.   +6 more
europepmc   +1 more source

Digenic HNF1A and ABCC8 variants provide mechanistic insight into early-onset diabetes.

J Clin Endocrinol Metab
Honda M, Honda R, Nomura TK, Nishikado Y, Takahashi Y, Hosomichi K, Tsunekawa S, Yabe D, Horikawa Y.   +8 more
europepmc   +1 more source