Results 81 to 90 of about 8,539 (162)

Assessing the association of the HNF1A G319S variant with C-reactive protein in Aboriginal Canadians: a population-based epidemiological study

Cardiovascular Diabetology, 2010
Background C-reactive protein (CRP), a biomarker of inflammation, has been associated with increased risk of developing cardiovascular disease. Common variants of the hepatocyte nuclear factor 1A (HNF1A) gene encoding HNF-1α have been associated with ...
Ley Sylvia H, Hegele Robert A, Connelly Philip W, Harris Stewart B, Mamakeesick Mary, Cao Henian, Gittelsohn Joel, Retnakaran Ravi, Zinman Bernard, Hanley Anthony J   +9 more
doaj   +1 more source

Assessment and translation of novel biomarkers for diagnosis of maturity onset diabetes of the young due to HNF1A variants [PDF]

, 2018
HNF1A-MODY is the most common form of monogenic diabetes, but due to low awareness among clinicians and limited availability of genetic testing in many countries, the majority of cases are misdiagnosed as type 1 or type 2 diabetes.
Agata Juszczak, Juszczak, Agata
core   +1 more source

Hepatic nuclear factor-1A (HNF1A) antisense long non-coding RNA subcellular location and function

, 2021
The human and mouse hepatocyte nuclear factor 1 homeobox A (HNF1A) gene locus expresses the HNF1A transcript and a long non-coding RNA in the antisense (HNF1A-AS1) direction. HNF1A-AS1 is expressed in numerous types of cancers.
Sepehri, Zahra
core  

HNF1A gene polymorphisms and cardiovascular risk factors in individuals with late-onset autosomal dominant diabetes: a cross-sectional study

Cardiovascular Diabetology, 2009
Background Type 2 diabetes mellitus (T2DM) is a genetically heterogeneous disease, hepatocyte nuclear factor-1 homeobox A (HNF1A) single-nucleotide polymorphisms (SNPs) playing a minor role in its pathogenesis.
Reis Andre F, Oliveira Marcos M, Kasamatsu Teresa S, Furuzawa Gilberto K, Giuffrida Fernando MA, Dib Sergio A   +5 more
doaj   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Meglitinide analogues in adolescent patients with HNF1A-MODY (MODY 3)

, 2014
For pediatric patients with hepatocyte nuclear factor-1A (HNF1A)-maturity-onset diabetes of the young (MODY 3), treatment with sulfonylureas is recommended.
Raile, K., Galler, A., Becker, M.
core   +1 more source

Genetic and clinical characteristics of patients with HNF1A gene variations from the German-Austrian DPV database

, 2011
OBJECTIVE: To determine prevalence, genetic and phenotype characteristics of patients with hepatocyte nuclear factor-1alpha (HNF1A) variants in the Diabetes Patienten Verlaufsdokumenation (DPV) multicentre database and to examine the influence of HNF1A ...
K Raile, Thon, A., Schober, E., A Thon, E Schober, Grulich-Henn, J., Awa, W.L., Raile, K., J Grulich-Henn, Meissner, T., T Meissner, W L Awa, Holl, R.W., R W Holl, _ _   +14 more
core   +1 more source

Corrigendum: A clinical case of pregnancy of a patient with a combination of two orphan diseases: familial partial lipodystrophy type 4 and hnf1a-mody on the background of therapy with recombinant human methionyl leptin (Diabetes mellitus. 2025;28(3). doi: 10.14341/DM13333)

Сахарный диабет
An error was identified in the article “A clinical case of pregnancy of a patient with a combination of two orphan diseases: familial partial lipodystrophy type 4 and HNF1A-MODY on the background of therapy with recombinant human methionyl leptin” by ...
N. V. Frolkova, E. R. Radkevich, E. O. Koksharova, F. F. Burumkulova, P. A. Vasiluev, I. R. Minniakhmetov, I. A. Eremina, M. V. Shestakova   +7 more
doaj   +1 more source

HNF1A is a Novel Oncogene and Central Regulator of Pancreatic Cancer Stem Cells

, 2017
The biological properties of pancreatic cancer stem cells (PCSCs) remain incompletely defined and the central regulators are unknown. By bioinformatic analysis of a PCSC-enriched gene signature, we identified the transcription factor HNF1A as a putative ...
Howard C. Crawford, Sumithra Urs, Ethan V. Abel, Jiaqi Shi, Meghna Waghray, Nikita Ramanathan, Diane M. Simeone, Emily Hotaling, Mats Ljungman, Masashi Goto, Michele L. Dziubinski, Brian Magnuson, Saji Abraham, Chandan Kumar-Sinha, Lidong Wang, Anthony A. Alaniz   +15 more
core   +1 more source

Issue Information

Journal of Diabetes Investigation, Volume 17, Issue 9, Page 1453-1456, September 2026.
wiley   +1 more source