Results 51 to 60 of about 8,814 (196)
Evaluation of Long Non-Coding RNAs: HNF1A-AS1 and MVIH Expressions and Their Clinical Significance in Human Gastric Cancer [PDF]
Journal of Genetic Resources, 2020 Gastric cancer is one of the most common cancers in the world. Late diagnosis is the main cause of the high rate of treatment failure and death among patients with gastric cancer; therefore identifying the molecular basis of cancer initiation and ...
Hasan Rahimi-Tamandegani +2 more
doaj +1 more source
Targeting FGFR4 abrogates HNF1A-driven metastasis in pancreatic ductal adenocarcinoma
Molecular CancerBackground We previously identified an oncogenic role for the transcription factor HNF1A in pancreatic ductal adenocarcinoma (PDAC). However, the role of HNF1A in the metastatic progression of PDAC remains unknown and targeting modalities for HNF1A ...
Katherine J. Crawford +11 more
doaj +1 more source
Cancer Medicine, 2020 Mounting literatures have revealed the crucial effects of long noncoding RNA (lncRNA) in various cancers, including glioma. HNF1A‐AS1, a novel lncRNA, is reported to modulate tumorigenesis and development of multiple cancers.
Jianheng Wu +6 more
doaj +1 more source
Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.Technological innovation through image analysis has become a reality. Radiation exposure is unavoidable during ERCP, yet reducing X‐ray dose degrades image quality. We evaluated an image‐processing technology (🄬Shimadzu) that reconstructs low‐dose fluoroscopic images to a quality comparable with standard‐dose images.
Mitsuru Okuno +9 more
wiley +1 more source
Cancer Cell International, 2019 Background There is growing evidence of the role of long non-coding RNAs (lncRNAs) in cervical cancer (CC). The objective was to discuss whether exosomal lncRNA HNF1A-AS1 impacted drug resistance in CC via binding to microRNA-34b (miR-34b) and regulating
Xiaoqiong Luo +7 more
doaj +1 more source
HNF1α maintains pancreatic α and β cell functions in primary human islets
JCI Insight, 2023 HNF1A haploinsufficiency underlies the most common form of human monogenic diabetes (HNF1A–maturity onset diabetes of the young [HNF1A-MODY]), and hypomorphic HNF1A variants confer type 2 diabetes risk.
Mollie F. Qian +9 more
doaj +1 more source
Variants of the HNF4A and HNF1A genes in patients with impaired glucose metabolism and dyslipidemia
Атеросклероз, 2022 Maturity onset diabetes of the young is a dominantly inherited form of monogenic diabetes, diagnosed mainly before the age of 35 years. Mutations in the HNF1A and HNF4A genes are associated with diabetes mellitus of the HNF1A-MODY and HNF4A-MODY subtypes,
Dinara E. Ivanoshchuk +7 more
doaj +1 more source
Hepatic Adenomas in Men: Diagnostic Considerations and Management in the Modern Era
Journal of Surgical Oncology, EarlyView.ABSTRACT Hepatic adenomas (HAs) are rare benign liver tumors traditionally associated with young women, yet contemporary epidemiologic trends reveal increasing recognition among men. Historically, universal resection in males has been recommended because of a nearly tenfold increased risk of malignant transformation as reported by Farges et al.
Teresa Belledent +9 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Tongue squamous cell carcinoma, the most aggressive subtype of oral squamous cell carcinoma, which is associated with high mortality, frequent recurrence, and early lymph‐node metastasis. Triptolide, a bioactive diterpenoid from Tripterygium wilfordii, exhibits broad anticancer activity.
Shan‐Shan Wang +3 more
wiley +1 more source
The expression profile of the HNF1A gene in human, mouse and rat.
, 2013 The expression profile of the HNF1A gene in human, mouse and rat is given. The species is given on the X-axis and the relative quantification of each isoform relative to the B2M gene is given on the Y-axis.
Lorna W. Harries (336166) +2 more
core +1 more source