Results 81 to 90 of about 6,154 (303)
ChemEngineeringThis study explores the dynamics of liquid holdup in a lab-scale co-current two-phase upflow moving packed bed reactor, specifically examining how superficial gas velocity influences the line average external liquid holdup at a fixed superficial liquid ...
Ali Toukan +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Formal Contracts, Relational Contracts, and the Holdup Problem [PDF]
We study the holdup problem in repeated transactions between a seller and a buyer such that the seller makes relation-specific investments in each period.
Hideshi Itoh, Hodaka Morita
core
Acoustic techniques for localizing holdup [PDF]
, 1996 Material that does not come out of a process as product or waste is called holdup. When this is fissile material, its location and quantity must be determined to improve safeguards and security as well as safety at the facility.
Vnuk, D.
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
A Reverse Holdup Problem [PDF]
, 2013 info:eu-repo/semantics ...
Estache, Antonio, Foucart, Renaud
openaire
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Learning to live with holdup [PDF]
, 1986 Holdup of special nuclear materials in processing facilities is recognized by facility operators and regulatory agencies as an insidious materials control and accounting problem.
Pillay, K. K. S., Picard, R. R.
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source