Results 81 to 90 of about 7,779 (297)

Formal Contracts, Relational Contracts, and the Holdup Problem [PDF]

open access: yes
We study the holdup problem in repeated transactions between a seller and a buyer such that the seller makes relation-specific investments in each period.
Hideshi Itoh, Hodaka Morita
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Experimental Investigation of Liquid Holdup in a Co-Current Gas–Liquid Upflow Moving Packed Bed Reactor with Porous Catalyst Using Gamma-Ray Densitometry

open access: yesChemEngineering
This study explores the dynamics of liquid holdup in a lab-scale co-current two-phase upflow moving packed bed reactor, specifically examining how superficial gas velocity influences the line average external liquid holdup at a fixed superficial liquid ...
Ali Toukan   +4 more
doaj   +1 more source

A Reverse Holdup Problem [PDF]

open access: yes, 2013
info:eu-repo/semantics ...
Estache, Antonio, Foucart, Renaud
openaire  

Rigidity in bilateral trade with holdup [PDF]

open access: yes
This paper studies bilateral trade in which the seller makes a hidden investment that influences the buyer's hidden valuation. In general it is impossible to implement both first-best efficient trade and efficient investment using budget-balanced trading
Zhao, Rui R.
core  

Acoustic techniques for localizing holdup [PDF]

open access: yes, 1996
Material that does not come out of a process as product or waste is called holdup. When this is fissile material, its location and quantity must be determined to improve safeguards and security as well as safety at the facility.
Vnuk, D.
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Uncertainty and Specific Investment with Weak Contract Enforcement [PDF]

open access: yes
The relationship between price uncertainty and specific investment is examined in a dynamic model that integrates the theories of real options and investment holdup.
Vercammen, James, Swinnen, Johan F.M.
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

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