Results 11 to 20 of about 20,496 (277)

Structures of the CcmABCD heme release complex at multiple states

Nature Communications, 2022
Bacterial ABC transporter complex CcmABCD, a part of cytochrome c maturation system, transfers heme from one binding partner (CcmC) to another (CcmE). Here authors describe high resolution cryo-EM structures of CcmABCD in multiple states and propose a ...
Jiao Li, Wan Zheng, Ming Gu, Long Han, Yanmei Luo, Koukou Yu, Mengxin Sun, Yuliang Zong, Xiuxiu Ma, Bing Liu, Ethan P. Lowder, Deanna L. Mendez, Robert G. Kranz, Kai Zhang, Jiapeng Zhu   +14 more
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Alteration of gastric microbiota and transcriptome in a rat with gastric intestinal metaplasia induced by deoxycholic acid

Frontiers in Microbiology, 2023
ObjectiveBile reflux plays a key role in the development of gastric intestinal metaplasia (GIM), an independent risk factor of gastric cancer. Here, we aimed to explore the biological mechanism of GIM induced by bile reflux in a rat model.MethodsRats ...
Zijing Xu, Ling Xiao, Shuaishuai Wang, Yuqin Cheng, Jianping Wu, Yufen Meng, Kaifan Bao, Junfeng Zhang, Chun Cheng   +8 more
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Treatment of COVID-19 by monoclonal antibodies and the traditional Chinese medicine

Medicine in Novel Technology and Devices, 2022
The mortality rate of the recent global pandemic corona virus disease 2019 (COVID-19) is currently as high as 7%. The SARS-CoV-2 virus is the culprit behind COVID-19.
Yuyan Ling, Yuxuan Dong, Qirui Li, Doudou Huang, Zhihui Li, Meijuan Chen   +5 more
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Aquaporin-9 facilitates liver regeneration following hepatectomy

Redox Biology, 2022
Aquaporin-9 (AQP9) is an aquaglyceroporin strongly expressed in the basolateral membrane of hepatocytes facing the sinusoids. AQP9 is permeable to hydrogen peroxide (H2O2) and glycerol as well as to water.
Bo Zhang, Dongyue Lv, Yang Chen, Weijue Nie, Yang Jiao, Junqi Zhang, Xiaoxiao Zhou, Xiao Wu, Siqing Chen, Tonghui Ma   +9 more
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Mechanism investigation of Caspase-8/GSDMC dependent immunogenic cell death induced by Ophiopogonin B in NSCLC cells

Pharmacological Research - Modern Chinese Medicine, 2022
Ophiopogonin B (OP-B) as a bioactive component of Radix Ophiopogon Japonicus has been reported to induce various kinds of cell death of non-small cell lung cancer (NSCLC) cells, while the underline mechanism is unknown.
Zhihui Li, Ling Gu, Qian Gao, Liqiu Li, Maozheng Sheng, Yuyan Ling, Cheng Hu, Menglin He, Xiongfei Zhang, Xu Shen, Xu Zhang, Meijuan Chen   +11 more
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Integrative medicine—designing holistic conceptual model

, 2021
Introduction: Integrative approaches in medicine are becoming increasingly popular due to the health promotion revival and the evidence-based clinical efficacy and cost-effectiveness of complementary and alternative medicine (CAM).
Vankova, Desislava; Medical University of Varna
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Integrative Medicine and Plastic Surgery: A Synergy-Not an Antonym [PDF]

, 2021
BACKGROUND Integrative medicine focuses on the human being as a whole-on the body, mind, and spirit-to achieve optimal health and healing. As a synthesis of conventional and complementary treatment options, integrative medicine combines the ...
Megas, Ioannis-Fivos; https://orcid.org/, Bong-Sung Kim, Jacqueline Bastiaanse, Friedemann Schad, Harald Matthes, Kröz, Matthias, Dascha Sophie Tolzmann, Tolzmann, Dascha Sophie, Grieb, Gerrit; https://orcid.org/, Matthias Kröz, Kim, Bong-Sung, Ioannis-Fivos Megas, Paul Christian Fuchs, Gerrit Grieb, Schad, Friedemann, Bastiaanse, Jacqueline, Fuchs, Paul Christian, Matthes, Harald   +17 more
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Perspectives and Ideas to Advance Integrative Medicine and Healthcare: Proceedings of the 4th Annual Jaseng Academic Conference

, 2023
The 4^th Annual Jaseng Academic conference (August 13, 2023) in Seoul, South Korea, was a pivotal event in the realm of integrative medicine.
Coggin-Carr, D, Trinh, K, Wieland, S, Lee, J, Cummings, M, Kien Trinh, Catherine Donahue, Susan Wieland, Lawrence Prokop, Jang, A, Andrew Jang, Shin, JS, Mike Cummings, Lee, MS, Myeong Soo Lee, Zaslawski, C, Jinho Lee, Donahue, C, Joon Shik Shin, Prokop, L, David Coggin-Carr, Christopher Zaslawski   +21 more
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BUB1B and circBUB1B_544aa aggravate multiple myeloma malignancy through evoking chromosomal instability

Signal Transduction and Targeted Therapy, 2021
Multiple myeloma (MM) is an incurable plasma cell malignancy in the bone marrow characterized by chromosome instability (CIN), which contributes to the acquisition of heterogeneity, along with MM progression, drug resistance, and relapse.
Xiaozhu Tang, Mengjie guo, Pinggang Ding, Zhendong Deng, Mengying Ke, Yuxia Yuan, Yanyan Zhou, Zigen Lin, Muxi Li, Chunyan Gu, Xiaosong Gu, Ye Yang   +11 more
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Induction of Ferroptosis by Ophiopogonin-B Through Regulating the Gene Signature AURKA in NSCLC

Frontiers in Oncology, 2022
Ferroptosis is a new type of iron-dependent programmed cell death. In recent years, its role in the diagnosis and treatment of multiple tumors, including non-small cell lung cancer (NSCLC), has been continuously observed.
Liqiu Li, Liqiu Li, Qian Gao, Jin Wang, Ling Gu, Ling Gu, Zhihui Li, Shiping Zhang, Cheng Hu, Menglin He, Yulin Wang, Zixuan Wang, Yongxiang Yi, Jin Fu, Xiongfei Zhang, Fei Ge, Meijuan Chen, Xu Zhang   +17 more
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