Results 21 to 30 of about 19,838 (208)

Targeting RFWD2 as an Effective Strategy to Inhibit Cellular Proliferation and Overcome Drug Resistance to Proteasome Inhibitor in Multiple Myeloma

Frontiers in Cell and Developmental Biology, 2021
The potential to overcome resistance to proteasome inhibitors is greatly related with ubiquitin-proteasome system during multiple myeloma (MM) treatment process.
Mengjie Guo, Mengjie Guo, Pinggang Ding, Zhen Zhu, Lu Fan, Yanyan Zhou, Shu Yang, Ye Yang, Chunyan Gu, Chunyan Gu   +9 more
doaj   +1 more source

Attentional vigilance of food information in disordered eating behaviors

Frontiers in Psychiatry, 2023
IntroductionDisordered eating behaviors (DEBs) are very common among female college students, which seriously endanger their health and well-being. Therefore, the study of the mechanism of DEBs can provide effective evidence for early detection and ...
Luyao Jin, Wenyue Han, Wenyue Han, Zheng Zheng   +3 more
doaj   +1 more source

Nano‐omics: Frontier fields of fusion of nanotechnology

Smart Medicine, 2023
Nanotechnology, an emerging force, has infiltrated diverse domains like biomedical, materials, and environmental sciences. Nano‐omics, an emerging fusion, combines nanotechnology with omics, boasting amplified sensitivity and resolution.
Xuan Wang, Weichen Xu, Jun Li, Chen Shi, Yuanyuan Guo, Jinjun Shan, Ruogu Qi   +6 more
doaj   +1 more source

A possible mechanism to the antidepressant-like effects of 20 (S)-protopanaxadiol based on its target protein 14-3-3 ζ

Journal of Ginseng Research, 2022
Background: Ginsenosides and their metabolites have antidepressant-like effects, but the underlying mechanisms remain unclear. We previously identified 14-3-3 ζ as one of the target proteins of 20 (S)-protopanaxadiol (PPD), a fully deglycosylated ...
Lin Chen, Ruimei Li, Feiyan Chen, Hantao Zhang, Zhu Zhu, Shuyi Xu, Yao Cheng, Yunan Zhao   +7 more
doaj   +1 more source

The antiviral and coronavirus-host protein pathways inhibiting properties of herbs and natural compounds - Additional weapons in the fight against the COVID-19 pandemic?

Journal of Traditional and Complementary Medicine, 2020
Introduction: As of March 11th, 2020, the World Health Organization declared the COVID-19 outbreak a pandemic. Articles published after the SARS-CoV-1 (2002) epidemic suggest that the use of an herbal-drug integrative medical approach could have ...
Andréa D. Fuzimoto, Ciro Isidoro
doaj   +1 more source

Icariin Inhibits Intestinal Inflammation of DSS-Induced Colitis Mice Through Modulating Intestinal Flora Abundance and Modulating p-p65/p65 Molecule

The Turkish Journal of Gastroenterology, 2021
Background: Ulcerative colitis, as a kind of inflammatory bowel disease (IBD) is characterized by abdominal pain. This study aimed to investigate the effect of icariin (ICA) on the intestinal microflora of colitis mice.
Haoran Zhang, Shixuan Zhuo, Danni Song, Leyao Wang, Junyi Gu, Junyan Ma, Yang Gu, Minghui Ji, Meijuan Chen, Yuanyuan Guo   +9 more
doaj   +1 more source

The Mediating Effect of Coping Style in the Relationship Between Depression and Disordered Eating Among Chinese Female Undergraduates

Frontiers in Psychology, 2020
The aim of the current study was to explore the relationship between depression and disordered eating in female undergraduates and the mediating role of coping style between depression and disordered eating.
Zheng Zheng, Wenyue Han, Yawen Li, Dongyan Wang, Simeng Gu, Fushun Wang   +5 more
doaj   +1 more source

G6PD promotes cell proliferation and dexamethasone resistance in multiple myeloma via increasing anti-oxidant production and activating Wnt/β-catenin pathway

Experimental Hematology & Oncology, 2022
Background Glucose-6-phosphate dehydrogenase (G6PD) as the rate-limiting enzyme in the pentose phosphate pathway (PPP) is well-established as an aberrantly expressed protein in numerous clinical diseases; however, its role in cancer, specifically in ...
Rui Li, Mengying Ke, Mingming Qi, Zhenru Han, Yuhao Cao, Zhendong Deng, Jinjun Qian, Ye Yang, Chunyan Gu   +8 more
doaj   +1 more source

Whole Transcriptome Analysis Identifies Platycodin D-Mediated RNA Regulatory Network in Non–Small-Cell Lung Cancer

Cells, 2022
Non–small-cell lung cancer (NSCLC) is one of the most fatal malignant tumors harmful to human health. Previous studies report that Platycodin D (PD) exhibits anti-tumor effects in multiple human cancers, including NSCLC, but the underlying mechanisms are
Shuyu Zheng, Zejuan Xie, Yanlin Xin, Wenli Lu, Hao Yang, Tianming Lu, Jun Li, Shanshan Wang, Keyu Cheng, Xi Yang, Ruogu Qi, Yongming Qiu, Yuanyuan Guo   +12 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source