Results 21 to 30 of about 3,333,537 (255)

Gold(I) selenium N-heterocyclic carbene complexes as potent antibacterial agents against multidrug-resistant gram-negative bacteria via inhibiting thioredoxin reductase

Redox Biology, 2023
Multidrug-resistant (MDR) Gram-negative bacteria have become a global threat to human life and health, and novel antibiotics are urgently needed. The thioredoxin (Trx) system can be used as an antibacterial target to combat MDR bacteria.
Xiuli Chen, Shibo Sun, Sheng Huang, Han Yang, Qing Ye, Lin Lv, Yanshan Liang, Jinjun Shan, Jianqiang Xu, Wukun Liu, Tonghui Ma   +10 more
doaj   +1 more source

Steroid 5α-Reductase Type I Induces Cell Viability and Migration via Nuclear Factor-κB/Vascular Endothelial Growth Factor Signaling Pathway in Colorectal Cancer

Frontiers in Oncology, 2020
Colorectal cancer (CRC) is a common malignant tumor of the digestive system. Steroid 5α-reductase type I (SRD5A1), as an important part of the steroid metabolism, converts testosterone to dihydrotestosterone and regulates sex hormone levels, which ...
Rongfang Wei, Rongfang Wei, Sixia Zhong, Li Qiao, Mengjie Guo, Miaomiao Shao, Suyu Wang, Bin Jiang, Ye Yang, Chunyan Gu, Chunyan Gu   +10 more
doaj   +1 more source

Targeting RFWD2 as an Effective Strategy to Inhibit Cellular Proliferation and Overcome Drug Resistance to Proteasome Inhibitor in Multiple Myeloma

Frontiers in Cell and Developmental Biology, 2021
The potential to overcome resistance to proteasome inhibitors is greatly related with ubiquitin-proteasome system during multiple myeloma (MM) treatment process.
Mengjie Guo, Mengjie Guo, Pinggang Ding, Zhen Zhu, Lu Fan, Yanyan Zhou, Shu Yang, Ye Yang, Chunyan Gu, Chunyan Gu   +9 more
doaj   +1 more source

Attentional vigilance of food information in disordered eating behaviors

Frontiers in Psychiatry, 2023
IntroductionDisordered eating behaviors (DEBs) are very common among female college students, which seriously endanger their health and well-being. Therefore, the study of the mechanism of DEBs can provide effective evidence for early detection and ...
Luyao Jin, Wenyue Han, Wenyue Han, Zheng Zheng   +3 more
doaj   +1 more source

A possible mechanism to the antidepressant-like effects of 20 (S)-protopanaxadiol based on its target protein 14-3-3 ζ

Journal of Ginseng Research, 2022
Background: Ginsenosides and their metabolites have antidepressant-like effects, but the underlying mechanisms remain unclear. We previously identified 14-3-3 ζ as one of the target proteins of 20 (S)-protopanaxadiol (PPD), a fully deglycosylated ...
Lin Chen, Ruimei Li, Feiyan Chen, Hantao Zhang, Zhu Zhu, Shuyi Xu, Yao Cheng, Yunan Zhao   +7 more
doaj   +1 more source

The antiviral and coronavirus-host protein pathways inhibiting properties of herbs and natural compounds - Additional weapons in the fight against the COVID-19 pandemic?

Journal of Traditional and Complementary Medicine, 2020
Introduction: As of March 11th, 2020, the World Health Organization declared the COVID-19 outbreak a pandemic. Articles published after the SARS-CoV-1 (2002) epidemic suggest that the use of an herbal-drug integrative medical approach could have ...
Andréa D. Fuzimoto, Ciro Isidoro
doaj   +1 more source

Nano‐omics: Frontier fields of fusion of nanotechnology

Smart Medicine, 2023
Nanotechnology, an emerging force, has infiltrated diverse domains like biomedical, materials, and environmental sciences. Nano‐omics, an emerging fusion, combines nanotechnology with omics, boasting amplified sensitivity and resolution.
Xuan Wang, Weichen Xu, Jun Li, Chen Shi, Yuanyuan Guo, Jinjun Shan, Ruogu Qi   +6 more
doaj   +1 more source

Competency-based evaluation tools for integrative medicine training in family medicine residency: a pilot study [PDF]

, 2007
Background As more integrative medicine educational content is integrated into conventional family medicine teaching, the need for effective evaluation strategies grows.
Craig Schneider, Susan Hadley, Maizes Victoria, Maizes, Victoria, Mary Koithan, Benjamin Kligler, Hadley Susan, Patricia Lebensohn, Hadley, Susan, Schneider Craig, Kligler Benjamin, Meg Hayes, Koithan, Mary, Schneider, Craig, Lebensohn, Patricia, Lebensohn Patricia, Victoria Maizes, Kligler, Benjamin, Koithan Mary, Hayes Meg, Hayes, Meg   +20 more
core   +2 more sources

Patients Receiving Integrative Medicine Effectiveness Registry (PRIMIER) of the BraveNet practice-based research network: Outcomes of the PRIMIER cohort [PDF]

, 2022
Objective: To evaluate the real-world effectiveness of integrative medicine treatment on quality of life using the Patients Receiving Integrative Medicine Effectiveness Registry (PRIMIER).
Gao, Qi, Dyer, Natalie L, Dusek, Jeffery A, Kim, Ryung S, McKee, M Diane, Abrams, Donald I, Hansen, Kathryn, Kligler, Benjamin   +7 more
core   +1 more source

The Mediating Effect of Coping Style in the Relationship Between Depression and Disordered Eating Among Chinese Female Undergraduates

Frontiers in Psychology, 2020
The aim of the current study was to explore the relationship between depression and disordered eating in female undergraduates and the mediating role of coping style between depression and disordered eating.
Zheng Zheng, Wenyue Han, Yawen Li, Dongyan Wang, Simeng Gu, Fushun Wang   +5 more
doaj   +1 more source