Results 131 to 140 of about 2,375 (233)

DIAGNOSTIC VALUE OF HOLOTRANSCOBALAMIN IN ASSESSMENT OF VITAMIN B12 DEFICIENCY

Clinical chemistry and laboratory medicine, 2017
Background Different neurological manifestations could be a consequence of vitamin B12 deficit, even when vitamin B12 concentrations are within reference intervals. In theory, measurement of amount of vitamin B12 available for the cells, known as holotranscobalamin, could be a more sensitive indicator of B12 deficiency in such cases.
Mandić, Dario, Mandić, Sanja, Horvat, Vesna, Sarić, Ivana, Šerić, Vatroslav   +4 more
openaire   +3 more sources

Single-blinded, stratified, dose ranging trial to assess pharmacokinetics and identify optimal dose of vitamin B12 in pregnancy in Tanzania [version 2; peer review: 1 approved, 3 approved with reservations]

Gates Open Research
Background Vitamin B12 is an essential cofactor for two enzymes that have critical functions in pregnancy, both for maternal health and fetal development.
Omar Lweno, Matthew D. Barberio, Victoria S. Reynolds, Sabina Mugusi, Kevin C. Klatt, Zohra Lukmanji, Mathangi Gopalakrishnan, Homa K. Ahmadzia, Fadhlun M. Alwy Al-beity, Leigh A. Martin, Amrita Arcot, Brooke Langevin, Ali Rahnavard, Emily R. Smith, Kelly Gallagher, Honorati Masanja, Alison D. Gernand   +16 more
doaj   +1 more source

Vitamin B-12 status, particularly holotranscobalamin II and methylmalonic acid concentrations, and hyperhomocysteinemia in vegetarians [PDF]

, 2003
Wolfgang Herrmann, Heike Schorr, Rima Obeid, Jürgen Geisel   +3 more
openalex   +1 more source

Rapid Restoration of Circulating Vitamin B12 Levels by Using Oral Sucrosomial^® Vitamin B12 in Metformin-Associated B12 Deficiency: Results from a Double-Blind, Placebo-Controlled Randomized Clinical Trial

Pharmaceutics
Background/Objectives: Vitamin B12 deficiency is common in individuals with type 2 diabetes mellitus (T2DM) receiving long-term metformin therapy, primarily due to impaired intestinal absorption.
Gabriele Conti, Allah W. Kalo, Ikram Ujjan, Aisha Aslam, Amjad Khan, Nazia M. Memon, Shair Z. Kakar, Naseer Ahmed, Shifa Zahid, Germano Tarantino, Elisa Brilli   +10 more
doaj   +1 more source

بررسی سطح سرمی ويتامين B12، Folate و هموسيستئين در سالمندان سالم تهرانی [PDF]

, 2009
زمينه و هدف: از آنجائيکه جذب کوبالامين اغلب در سالمندان کاهش می‌يابد، کمبود ويتامين B12 يکی از مشکلات شايع در اين افراد است. تحقيقات اخير نشان می‌دهند که ميزان ناکافی ويتامين B12 ممکن است خطر ابتلا به بيماری‌های آترواسکلروتيک و نورودژنراتيو را افزايش دهد.
خدابنده‌لو, نیلوفر, فروغان, مهشید, قلعه‌بندی, میرفرهاد, نجومی, مرضیه, وکيلی, مسعود   +4 more
core  

Clinical case of funicular myelosis in combination with a concomitant genetic predisposition to folate cycle disorder

Medičnì Perspektivi
Funicular myelosis (sub­acute combined degeneration) is a disease characterized by the development of degeneration of the posterior and lateral cords of the spinal cord.
O.D. Shulga , E.A. Popko, A.S. Chabanova , O.G. Kotsiuba , Q. Hussain   +4 more
doaj   +1 more source

PWE-093 Screening with Holotranscobalamin is Superior to Serum B12 in Identifying Vitamin B12 Deficiency in Patients with Crohn’S Disease [PDF]

, 2013
Mark G. Ward, Viraj C. Kariyawasam, Paul Blaker, Kamal Patel, Rishi Goel, Agata Sobczyńska‐Malefora, A. Ajaegbu, Dominic J. Harrington, Simon H. Anderson, Jeremy Sanderson, Peter M. Irving   +10 more
openalex   +1 more source

P3–126: Vitamin B12, holotranscobalamin and risk of cognitive decline: 10–year follow–up of the Oxford Healthy Aging Project [PDF]

, 2006
Robert Clarke, Jacqueline Birks, Ebba Nexø, Kathleen Emmens, Joern Schneede, Per Magne Ueland, John M. Scott, Anne M. Molloy, John Grimley-Evans   +8 more
openalex   +1 more source

The Application of Holotranscobalamin and Methylmalonic Acid in Hospital Patients and Total Vitamin B12 in Primary Care Patients to Assess Low Vitamin B12 Status [PDF]

, 2015
Agata Sobczyńska‐Malefora, Matthew Critcher, Dominic J. Harrington, V Devalia, M Hamilton, A Molloy, A Hunt, D Harrington, S Robinson, R Clarke, Grimley Evans, J Schneede, J Nexo, E Bates, C, J Lindenbaum, E Healton, D Savage, J Brust, T Garrett, J Arendt, E Nexo, S Heil, R De Jonge, M De Rotte, M Van Wijnen, R Heiner-Fokkema, W Herrmann, R Obeid, R Obeid, W Herrmann, A Sobczynska-Malefora, R Gorska, M Pelisser, P Ruwona, B Witchlow, Abbott Diagnostics, R Gorska, D Harrington, P Roberts, A Vogiatzoglou, A Oulhaj, A Smith, E Nurk, C Drevon, E Erdogan, G Nelson, A Rockwood, Frank, Z Lloyd-Wright, A Hvas, J Moller, T Sanders, E Nexo, A Sobczynska-Malefora, D Harrington, K Voong, M Shearer, A Levey, J Bosch, J Lewis, T Greene, N Rogers, M Bor, E Nexo, A Remacha, M Sarda, C Canals, J Queralto, E Zapico, D Osborne, A Sobczynska-Malefora, J Francis, D Sheridan, A Samanta, F Nichol, O Jolobe, R Clarke, H Refsum, J Birks, J Evans, C Johnston, G Alfthan, M Laurinen, L Valsta, T Pastinen, A Aro, E Yetley, C Pfeiffer, K Phinney, R Bailey, S Blackmore, R Bailey, R Durazo-Arvizu, R Carmel, R Green, C Pfeiffer, R Carmel, E Nexo, A Christensen   +99 more
openalex   +1 more source

Hyperhomocysteinemia - unrecognized and neglected (Homocysteine - a useful marker of methylation disorders from deficit of holotranscobalamin and folate) [PDF]

, 2009
J Hyánek, L Dubská, H Pejznochová, František Pehal, S Vaingátová, V Martiníková   +5 more
openalex   +1 more source