Results 111 to 120 of about 4,469,958 (240)
Advanced Science, EarlyView.This study shows that propofol modulates fear‐memory reconsolidation in mice. It works by suppressing D2 receptor‐expressing neurons within the medial prefrontal cortex and their connections to the basolateral amygdala. D2‐receptor agonists reproduce this fear‐reducing effect, offering potential non‐anesthetic therapeutic strategies for trauma‐related ...
Jie Li +11 more
wiley +1 more source
Home Cage Monitoring: Where We Are and What We Need?
Abstract This book presents the first comprehensive overview of Home Cage Monitoring (HCM) in rodents, examining how these technologies may contribute to addressing some of the key challenges in animal research. HCM systems provide a method for continuous, automated observation of laboratory animals within their home environment ...
Anna Kiryk +3 more
openaire +1 more source
Continuous monitoring of physical activity in the home cage.
, 2018 A. Heat maps depicting baseline-normalized physical activity per hour (x-axis) throughout the days of the experiment (y-axis) as measured in the home cage, averaged across the non-implanted and experimental groups separately.
Pieter M. Goltstein (260749) +4 more
core +1 more source
Stakeholder Perspectives on Therapeutic and Safe Building Design in Residential Care
Australian Journal of Social Issues, EarlyView.ABSTRACT Residential care is a form of out‐of‐home care that plays a critical role in supporting vulnerable young people in Australia. However, there is an evidence gap regarding the built environment in this context. This research aimed to explore the perspectives of key stakeholders in residential care in Victoria, Australia, regarding design that ...
Carmen Schroder +3 more
wiley +1 more source
Evaluation of the Digital Ventilated Cage® system for circadian phenotyping
Scientific ReportsThe study of circadian rhythms has been critically dependent upon analysing mouse home cage activity, typically employing wheel running activity under different lighting conditions.
Selma Tir +2 more
doaj +1 more source
Enhancing Animal Welfare Through Home Cage Monitoring Systems
Abstract Home cage monitoring (HCM) is increasingly being used in scientific studies but its application in the field of animal welfare is lagging. Advances in animal research are predominantly driven by scientific projects whose primary goal is increasing scientific knowledge but not animal welfare. Harnessing the potential of HCM to
Heidrun Potschka +5 more
openaire +1 more source
Animal Research and One Health, EarlyView.Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen +5 more
wiley +1 more source
Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality
BMEMat, EarlyView.Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim +9 more
wiley +1 more source
Vocalisations as a potential indicator of parturition in C57BL/6J mice
Animal WelfareBreeding management in laboratory rodents is challenging, particularly around parturition and the neonatal period, where cage disturbance is often avoided in an attempt to limit neonatal mortality.
Sara Capas-Peneda +8 more
doaj +1 more source
The effect of quinpirole on locomotor activity in home cage monitoring system
Neuroscience Applied, 2022 J. Park, K. Kim, H. Suh, H. Lim, E. Moon
openaire +1 more source