A single amino acid can determine the DNA binding specificity of homeodomain proteins
Many Drosophila developmental genes contain a DNA binding domain encoded by the homeobox. This homeodomain contains a region distantly homologous to the helix-turn-helix motif present in several prokaryotic DNA binding proteins.
Treisman, J. +4 more
core +1 more source
Characterization of Homeodomain Proteins at the Aβ Sublocus in <i>Schizophyllum commune</i> and Their Role in Sexual Compatibility and Development. [PDF]
Chu C, Li D, Liu C.
europepmc +1 more source
Modular control of glutamatergic neuronal identity in C. elegans by distinct homeodomain proteins. [PDF]
Serrano-Saiz E +5 more
europepmc +1 more source
Targets of the Sex Inducer homeodomain proteins are required for fungal development and virulence in Cryptococcus neoformans. [PDF]
Mead ME, Stanton BC, Kruzel EK, Hull CM.
europepmc +1 more source
Cross-Kingdom Structural Conservation and Diversification of Homeodomains Across Major Eukaryotic Lineages. [PDF]
Buarante GE +4 more
europepmc +1 more source
The RHOX homeodomain proteins regulate the expression of insulin and other metabolic regulators in the testis. [PDF]
MacLean JA +6 more
europepmc +1 more source
Crystal structure of the NKX2-1 homeodomain bound to a palindromic DNA recognition sequence. [PDF]
Mohandas A, Nam HJ.
europepmc +1 more source
CLOCK/BMAL1 interactome uncovers homeodomain factors as tissue regulators. [PDF]
Aygenli F +13 more
europepmc +1 more source
Best practices for isothermal titration calorimetry of protein-DNA interactions. [PDF]
Mekkaoui F +3 more
europepmc +1 more source
Proteasome inhibition alleviates proteinuria in Lmx1b knock-in mice with dysfunctional LIM domains. [PDF]
Hermens J +11 more
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