Results 111 to 120 of about 1,590,984 (213)

Role of the tomato MARS1/ROUGH gene encoding a LYSINE‐SPECIFIC HISTONE DEMETHYLASE 1 in adventitious root and fruit skin formation

open access: yesJournal of Integrative Plant Biology, Volume 68, Issue 10, Page 3644-3669, October 2026.
The tomato mars1/rough mutant displays enhanced root regeneration and rough fruits due to ectopic cell proliferation. The causal gene encodes a lysine‐specific histone demethylase that normally maintains gene silencing. Its loss alters histone methylation, upregulating several genes, including those B‐type cyclins involved in tissue‐specific cellular ...
Eduardo Larriba   +14 more
wiley   +1 more source

Deciphering the pathogenicity of three NKX2-1 variants in ultra-severe forms of childhood interstitial lung disease.

open access: yesPLoS ONE
IntroductionThe transcription factor NK2 homeobox1 (NKX2-1), associated with brain lung thyroid syndrome, regulates the transcription of surfactant proteins, thyroglobulin (TG) and thyroid peroxidase (TPO).
Yohan David Soreze   +12 more
doaj   +1 more source

Genome-wide analysis and expression profiling of zinc finger homeodomain (ZHD) family genes reveal likely roles in organ development and stress responses in tomato

open access: yesBMC Genomics, 2017
Background Zinc finger homeodomain proteins (ZHD) constitute a plant-specific transcription factor family with a conserved DNA binding homeodomain and a zinc finger motif.
Khadiza Khatun   +9 more
doaj   +1 more source

Combinatorial cis‐regulatory elements shape temporal effector expression in Ustilago maydis

open access: yesMolecular Plant Pathology, Volume 27, Issue 10, October 2026.
We identified promoter motifs associated with infection phases in Ustilago maydis and analysed their positional distribution relative to transcription start sites and generated a synthetic minimal promoter that drives in‐plant gene expression. ABSTRACT Plant‐pathogenic fungi secrete small proteins, termed effectors, to reprogramme host metabolism and ...
Georgios Saridis   +7 more
wiley   +1 more source

HOXA10 controls osteoblastogenesis by directly activating bone regulatory and phenotypic genes [PDF]

open access: yes, 2007
HOXA10 is necessary for embryonic patterning of skeletal elements, but its function in bone formation beyond this early developmental stage is unknown. Here we show that HOXA10 contributes to osteogenic lineage determination through activation of Runx2 ...
van Wijnen, AJ   +19 more
core   +1 more source

A laser capture microdissection‐based transcriptome analysis on salt glands highlights salt secretion mechanism in mangrove plant Avicennia marina

open access: yesThe Plant Journal, Volume 128, Issue 1, October 2026.
SUMMARY Salt glands, developed in the epidermis of salt‐secreting mangrove plant Avicennia marina leaves and specialized in salt secretion, are critical for improving the survival under high saline habitats. However, the salt secretion mechanism in A. marina remains poorly understood. In this study, laser capture microdissection was employed to isolate
Ming‐Yue Wei   +13 more
wiley   +1 more source

Proteins

open access: yes, 2004
Solvation energy calculation is one of the main difficulties for the estimation of protein-ligand binding free energy and the correct scoring in docking studies.
Zhou, JJ, Wang, Q, Pei, JF, Lai, LH
core   +1 more source

The SPL8‐YAB3/TCP19 module integrates transcriptional and protein–protein regulatory mechanisms to orchestrate anther development in Arabidopsis

open access: yesThe Plant Journal, Volume 128, Issue 1, October 2026.
SUMMARY SQUAMOSA PROMOTER BINDING PROTEIN‐LIKE 8 (SPL8) is a plant‐specific transcription factor essential for anther development, but its regulatory partners and downstream mechanisms remain largely unknown. We identified 26 SPL8‐interacting transcription factors by yeast two‐hybrid screening and bimolecular fluorescence complementation (BiFC) assays,
Tingting Li, Lei Zhang, Shuping Xing
wiley   +1 more source

Isoforms of hepatocyte nuclear factor-6 differ in DNA-binding properties, contain a bifunctional homeodomain, and define the new ONECUT class of homeodomain proteins

open access: yes, 1998
Hepatocyte nuclear factor-6 (HNF-6) contains a single cut domain and a homeodomain characterized by a phenylalanine at position 48 and a methionine at position 50.
Rousseau, Guy   +3 more
core   +1 more source

Physico-chemical characterization of the interaction between thyroid transcription factor 1 (TTF-1) and DNA [PDF]

open access: yes, 2010
The thyroid transcription factor 1 (TTF-1) is a tissue-specific transcription factor involved in the development of thyroid and lung. It is a protein of 371 amino acids that possesses two independent transcriptional activation domains, one located in the
Carullo, Paola
core   +1 more source

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