Results 91 to 100 of about 65,874 (228)

Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro

Genomics Data, 2016
This work pertains to GEO submission GSE36672, in vivo and in vitro genome wide binding (ChIP-Seq) of Bapx1/Nkx3.2 and Sox9 proteins. We have previously shown that data from a genome wide binding assay combined with transcriptional profiling is an ...
Sumantra Chatterjee, Petra Kraus, V. Sivakamasundari, Sook Peng Yap, Vibhor Kumar, Shyam Prabhakar, Thomas Lufkin   +6 more
doaj   +1 more source

The use of information theory in evolutionary biology

, 2011
Information is a key concept in evolutionary biology. Information is stored in biological organism's genomes, and used to generate the organism as well as to maintain and control it. Information is also "that which evolves". When a population adapts to a
Adami, Adami, Adami, Adami, Adami, Adami, Ash, Atchley, Ay, Ay, Ay, Balduzzi, Balduzzi, Barrick, Basharin, Benner, Bialek, Billeter, Blount, Callahan, Carothers, Clarke, Cooper, Cover, da Silva, Darwin, Eddy, Edlund, Ewens, Federhen, Finn, Fletcher, Fletcher, Futuyma, Garcia-Horsman, Hartl, Iliopoulos, Jühling, Klyubin, Korber, Kryazhimskiy, Landauer, Lenski, Lenski, Lenski, Levy, Li, Linsker, Lungarella, Lungarella, Maynard Smith, McGill, Pauling, Polani, Queller, Rivoire, Robinson, Schneidman, Scott, Shannon, Sporns, Sporns, Taanman, Thornton, Tononi, Tononi, Tononi, Tononi, Tononi, Tononi, Tononi, Tononi, van der Graaff, Waddington, Wahl, Wang, Wang, Wiener, Woods, Zahedi   +79 more
core   +1 more source

ZINC-FINGER interactions mediate transcriptional regulation of hypocotyl growth in Arabidopsis [PDF]

, 2018
Integration of environmental signals and interactions among photoreceptors and transcriptional regulators is key in shaping plant development. TANDEM ZINC-FINGER PLUS3 (TZP) is an integrator of light and photoperiodic signaling that promotes flowering in
Breton, Ghislain, Chory, Joanne, Davidson, Mhairi L.H., Herzyk, Pawel, Kaiserli, Eirini, Kay, Steve A., Nastase, Ana-Maria, O'Donnell, Liz, Perrella, Giorgio, Pruneda-Paz, Jose L.   +9 more
core   +1 more source

Chromodomain Helicase DNA–Binding Proteins and Spermatogenesis: Current Advances

Andrology, EarlyView.
ABSTRACT Background Male infertility is a prevalent clinical condition, with approximately one‐third of cases classified as idiopathic, frequently stemming from impaired spermatogenesis because of dysregulated gene expression. Chromodomain helicase DNA‐binding (CHD) proteins are central chromatin remodelers that orchestrate this epigenetic regulation ...
Mingrui Zhang, Di Liu, Guoqiang Liu, Minggang Zhu, Feng Pan   +4 more
wiley   +1 more source

Ring the BELL and tie the KNOX: Roles for TALEs in gynoecium development

Frontiers in Plant Science, 2014
Carpels are leaf-like structures that bear ovules, and thus play a crucial role in the plant life cycle. In angiosperms, carpels are the last organs produced by the floral meristem and they differentiate a specialized meristematic tissue from which ...
Nicolas eArnaud, Véronique ePautot
doaj   +1 more source

Purification and characterization of a DNA-binding recombinant PREP1:PBX1 complex. [PDF]

PLoS ONE, 2015
Human PREP1 and PBX1 are homeodomain transcriptional factors, whose biochemical and structural characterization has not yet been fully described. Expression of full-length recombinant PREP1 (47.6 kDa) and PBX1 (46.6 kDa) in E.
Lisa Mathiasen, Chiara Bruckmann, Sebastiano Pasqualato, Francesco Blasi   +3 more
doaj   +1 more source

Trithorax group proteins: switching genes on and keeping them active [PDF]

, 2011
Cellular memory is provided by two counteracting groups of chromatin proteins termed Trithorax group (TrxG) and Polycomb group (PcG) proteins. TrxG proteins activate transcription and are perhaps best known because of the involvement of the TrxG protein ...
Cavalli, G., Iovino, N., Martinez, A., Schuettengruber, B.   +3 more
core   +1 more source

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, EarlyView.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source

The HOXC6 homeodomain-containing proteins.

The international journal of biochemistry & cell biology, 1998
The HOXC6 homeodomain-containing proteins act as transcription factors in the genetic control of multiple genes involved in development and cell differentiation. Two HOXC6 polypeptides are encoded by a single homeobox ('HOX') gene described as 'master gene' for the crucial role it plays in the patterning and axial morphogenesis of multiple species ...
Chariot, Alain, Gielen, jacques
openaire   +2 more sources

The ALX4 dimer structure provides insight into how disease alleles impact function

Nature Communications
How homeodomain proteins gain sufficient DNA binding specificity to regulate diverse processes is a long-standing question. Here, we determine how the ALX4 Paired-like protein achieves DNA binding specificity for a TAAT–NNN–ATTA dimer site. We first show
Brittany Cain, Zhenyu Yuan, Evelyn Thoman, Rhett A. Kovall, Brian Gebelein   +4 more
doaj   +1 more source