Gene turnover in the common ancestor of all C4 grasses
Understanding how plants evolve more efficient photosynthesis is important in a warming world where improving crop productivity and resilience is a global priority. By generating the first reference genomes for an early‐diverging group of grasses called the Aristidoideae, we were able to reconstruct the genetic makeup of the last common ancestor of all
Lara Pereira +6 more
wiley +1 more source
The third helix of the homeodomain of paired class homeodomain proteins acts as a recognition helix both for DNA and protein interactions [PDF]
The transcription factor Pax6 is essential for the development of the eyes and the central nervous system of vertebrates and invertebrates. Pax6 contains two DNA-binding domains; an N-terminal paired domain and a centrally located homeodomain. We have previously shown that the vertebrate paired-less isoform of Pax6 (Pax6DeltaPD), and several other ...
Bruun, Jack-Ansgar +7 more
openaire +3 more sources
White-Opaque Switching in Candida albicans Is Controlled by Mating-Type Locus Homeodomain Proteins and Allows Efficient Mating [PDF]
Discovered over a decade ago, white-opaque switching in the human fungal pathogen Candida albicans is an alternation between two quasistable, heritable transcriptional states.
Johnson, Alexander D., Miller, Mathew G.
core +1 more source
The proline rich homeodomain protein PRH/Hhex forms stable oligomers that are highly resistant to denaturation. [PDF]
Many transcription factors control gene expression by binding to specific DNA sequences at or near the genes that they regulate. However, some transcription factors play more global roles in the control of gene expression by altering the architecture of ...
Anshuman Shukla +3 more
doaj +1 more source
Papillary Thyroid Cancer With Cutaneous Metastasis: A Case Report and Literature Review
ABSTRACT Background Cutaneous metastasis of papillary thyroid carcinoma is rare, which may present as slowly growing nodules, erythematous papules, or ulcerative nodules. The pathophysiological mechanisms of skin metastasis in thyroid cancer remain unclear.
Yi‐Qing Gao +3 more
wiley +1 more source
Multiallelic recognition: Nonself-dependent dimerization of the bE and bW homeodomain proteins in ustilago maydis [PDF]
In the plant pathogenic fungus Ustilago maydis, sexual and pathogenic development are controlled by the multiallelic b mating-type locus. The b locus encodes a pair of unrelated homeodomain proteins termed bE and bW, with allelic differences clustering ...
Bölker, Michael +4 more
core +1 more source
Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro
This work pertains to GEO submission GSE36672, in vivo and in vitro genome wide binding (ChIP-Seq) of Bapx1/Nkx3.2 and Sox9 proteins. We have previously shown that data from a genome wide binding assay combined with transcriptional profiling is an ...
Sumantra Chatterjee +6 more
doaj +1 more source
Hox Gene Variation Drives Morphological Specialization of Humpback Grouper Cromileptes altivelis
Cromileptes altivelis exhibits a distinctive “sunken head and humpback” morphology, formed through cranial remodeling. Genetic analyses identified unique amino acid variants in Hoxa7a and Hoxa10b, with functional tests confirming their role in enhancing osteoblast activity and driving cranial remodeling.
Xiaoying Cao +4 more
wiley +1 more source
Molecular effects of novel mutations in Hesx1/HESX1 associated with human pituitary disorders [PDF]
The homeobox gene Hesx1/HESX1 has been implicated in the establishment of anterior pattern in the central nervous system (CNS) in a number of vertebrate species.
Tyrell, R +17 more
core
Ring the BELL and tie the KNOX: Roles for TALEs in gynoecium development
Carpels are leaf-like structures that bear ovules, and thus play a crucial role in the plant life cycle. In angiosperms, carpels are the last organs produced by the floral meristem and they differentiate a specialized meristematic tissue from which ...
Nicolas eArnaud, Véronique ePautot
doaj +1 more source

