Results 1 to 10 of about 119,722 (304)

Aberrant expression of NKL homeobox genes HMX2 and HMX3 interferes with cell differentiation in acute myeloid leukemia.

PLoS ONE, 2020
The NKL-code describes normal expression patterns of NKL homeobox genes in hematopoiesis. Aberrant expression of NKL homeobox gene subclass members have been reported in several hematopoietic malignancies including acute myeloid leukemia (AML).
Stefan Nagel, Claudia Pommerenke, Corinna Meyer, Roderick A F MacLeod, Hans G Drexler   +4 more
doaj   +1 more source

Virus-induced gene complementation reveals a transcription factor network in modulation of tomato fruit ripening [PDF]

, 2012
Plant virus technology, in particular virus-induced gene silencing, is a widely used reverse- and forward-genetics tool in plant functional genomics. However the potential of virus technology to express genes to induce phenotypes or to complement mutants
Fan, Zaifeng, Gallusci, Philippe, Giovannoni, James J., Hong, Yiguo, Jackson, Stephen D., Jin, Mingfei, Lai, Tongfei, Liu, Yule, Qin, Cheng, Rolin, Dominique, Shi, Nongnong, Wang, Huizhong, Wu, Zirong, Zhang, Hang, Zhong, Silin, Zhou, Tao   +15 more
core   +3 more sources

A conserved cluster of three PRD-class homeobox genes (homeobrain, rx and orthopedia) in the Cnidaria and Protostomia

EvoDevo, 2010
Background Homeobox genes are a superclass of transcription factors with diverse developmental regulatory functions, which are found in plants, fungi and animals.
Mazza Maureen E, Pang Kevin, Reitzel Adam M, Martindale Mark Q, Finnerty John R   +4 more
doaj   +1 more source

Transcriptomic comparison analysis across seven developmental stages of the Triatoma rubrofasciata, a vector of Chagas disease

BMC Genomics
Background Triatoma rubrofasciata is an obligate hematophagous insect and a primary vector of Trypanosoma cruzi, the etiological agent of Chagas disease, with a widespread global distribution. In addition to Try. cruzi, T.
Lei Duan, Yunjia Tian, Ziyi Wang, Limin Yang, Yunhai Guo, Yuanyuan Li, Zhengbin Zhou, Yong Shen, Yi Zhang, Qin Liu   +9 more
doaj   +1 more source

A symphony of inner ear developmental control genes

BMC Genetics, 2010
The inner ear is one of the most complex and detailed organs in the vertebrate body and provides us with the priceless ability to hear and perceive linear and angular acceleration (hence maintain balance).
Kraus Petra, Chatterjee Sumantra, Lufkin Thomas   +2 more
doaj   +1 more source

Autism-associated SNPs in the clock genes _npas2_, _per1_ and the homeobox gene _en2_ alter DNA sequences that show characteristics of microRNA genes. [PDF]

, 2008
Intronic single nucleotide polymorphisms (SNPs) in the clock genes _npas2_ and _per1_ and the homeobox gene _en2_ are reported to be associated with autism.
Brad Nicholas, Dawn C. Wimpory, Michael J. Owen, Thomas Caspari   +3 more
core   +1 more source

A dynamic regulome of shoot-apical-meristem-related homeobox transcription factors modulates plant architecture in maize

Genome Biology
Background The shoot apical meristem (SAM), from which all above-ground tissues of plants are derived, is critical to plant morphology and development. In maize (Zea mays), loss-of-function mutant studies have identified several SAM-related genes, most ...
Zi Luo, Leiming Wu, Xinxin Miao, Shuang Zhang, Ningning Wei, Shiya Zhao, Xiaoyang Shang, Hongyan Hu, Jiquan Xue, Tifu Zhang, Fang Yang, Shutu Xu, Lin Li   +12 more
doaj   +1 more source

Homeobox genes in gut development

Gut, 2002
Classical descriptions of gut development specify subdivision into foregut, midgut, and hindgut together with their derivatives. This is based on the anatomical localisation of the anterior and posterior intestinal portals separating the roof of the yolk sac from the foregut and hindgut diverticulae.
openaire   +4 more sources

IRX-related homeobox gene MKX is a novel oncogene in acute myeloid leukemia.

PLoS ONE
Homeobox genes encode transcription factors which organize differentiation processes in all tissue types including the hematopoietic compartment. Recently, we have reported physiological expression of TALE-class homeobox gene IRX1 in early myelopoiesis ...
Stefan Nagel, Corinna Meyer, Claudia Pommerenke   +2 more
doaj   +1 more source

Mutual information for examining correlations in DNA

, 2004
This paper examines two methods for finding whether long-range correlations exist in DNA: a fractal measure and a mutual information technique. We evaluate the performance and implications of these methods in detail.
A. ALLISON, D. ABBOTT, Dover G. A., Joset F., M. J. BERRYMAN   +4 more
core   +2 more sources