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The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases [PDF]
Homeobox genes constitute a large family of transcription factors that act as master regulators involved in multiple fundamental processes such as development and cell differentiation.
Maedeh Dadzadi +5 more
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Functions of LIM-homeobox genes
Homeobox genes play fundamental roles in development. They can be subdivided into several subfamilies, one of which is the LIM-homeobox subfamily. The primary structure of LIM-homeobox genes has been remarkably conserved through evolution. Have their functions similarly been conserved?
O, Hobert, H, Westphal
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The Role of NKL Homeobox Genes in T-Cell Malignancies
Homeobox genes encode transcription factors controlling basic developmental processes. The homeodomain is encoded by the homeobox and mediates sequence-specific DNA binding and interaction with cofactors, thus operating as a basic regulatory platform ...
Stefan Nagel
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A comparative analysis of transcription factor expression during metazoan embryonic development [PDF]
During embryonic development, a complex organism is formed from a single starting cell. These processes of growth and differentiation are driven by large transcriptional changes, which are following the expression and activity of transcription factors ...
Adryan, Boris, Schep, Alicia
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Widespread employment of conserved C. elegans homeobox genes in neuronal identity specification
Homeobox genes are prominent regulators of neuronal identity, but the extent to which their function has been probed in animal nervous systems remains limited.
Molly B. Reilly +18 more
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CUT homeobox genes: transcriptional regulation of neuronal specification and beyond
CUT homeobox genes represent a captivating gene class fulfilling critical functions in the development and maintenance of multiple cell types across a wide range of organisms.
Eduardo Leyva-Díaz
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Objective. Homeobox genes play a fundamental role in the embryogenesis, but some of them have been linked to oncogenesis. The present study is aimed to investigate the impact of glucose and glutamine deprivations on the expression of homeobox genes such ...
Krasnytska Dariia O. +8 more
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Homeobox genes encode transcription factors which control basic processes in development and differentiation. Concerning the sequence conservation in their homeobox, these genes are arranged into particular groups sharing evolutionary ancestry and ...
Stefan Nagel
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The Homeobox Genes of Caenorhabditis elegans and Insights into Their Spatio-Temporal Expression Dynamics during Embryogenesis. [PDF]
Homeobox genes play crucial roles for the development of multicellular eukaryotes. We have generated a revised list of all homeobox genes for Caenorhabditis elegans and provide a nomenclature for the previously unnamed ones.
Jürgen Hench +10 more
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Genome-wide analysis of homeobox gene family in legumes: identification, gene duplication and expression profiling. [PDF]
Homeobox genes encode transcription factors that are known to play a major role in different aspects of plant growth and development. In the present study, we identified homeobox genes belonging to 14 different classes in five legume species, including ...
Annapurna Bhattacharjee +3 more
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