Results 11 to 20 of about 73,647 (262)

An Orthologous Epigenetic Gene Expression Signature Derived from Differentiating Embryonic Stem Cells Identifies Regulators of Cardiogenesis. [PDF]

open access: yesPLoS ONE, 2015
Here we used predictive gene expression signatures within a multi-species framework to identify the genes that underlie cardiac cell fate decisions in differentiating embryonic stem cells.
Brian W Busser   +5 more
doaj   +1 more source

Homeobox Gene Expression Dysregulation as Potential Diagnostic and Prognostic Biomarkers in Bladder Cancer

open access: yesDiagnostics, 2023
Homeobox genes serve as master regulatory transcription factors that regulate gene expression during embryogenesis. A homeobox gene may have either tumor-promoting or tumor-suppressive properties depending on the specific organ or cell lineage where it ...
Fee-Wai Chin   +2 more
doaj   +1 more source

Classification and nomenclature of all human homeobox genes

open access: yesBMC Biology, 2007
Background The homeobox genes are a large and diverse group of genes, many of which play important roles in the embryonic development of animals. Increasingly, homeobox genes are being compared between genomes in an attempt to understand the evolution of
Bruford Elspeth A   +2 more
doaj   +1 more source

The dynamics of vertebrate homeobox gene evolution: gain and loss of genes in mouse and human lineages

open access: yesBMC Evolutionary Biology, 2011
Background Homeobox genes are a large and diverse group of genes, many of which play important roles in transcriptional regulation during embryonic development.
Holland Peter WH, Zhong Ying-fu
doaj   +1 more source

Diversity, phylogeny and expression patterns of Pou and Six homeodomain transcription factors in hydrozoan jellyfish Craspedacusta sowerbyi. [PDF]

open access: yesPLoS ONE, 2012
Formation of all metazoan bodies is controlled by a group of selector genes including homeobox genes, highly conserved across the entire animal kingdom.
Miluse Hroudova   +7 more
doaj   +1 more source

The impact of glutamine deprivation on the expression of MEIS3, SPAG4, LHX1, LHX2, and LHX6 genes in ERN1 knockdown U87 glioma cells

open access: yesEndocrine Regulations, 2022
Objective. The aim of the current study was to investigate the expression of genes encoded homeobox proteins such as MEIS3 (Meis homeobox 3), SPAG4 (sperm associated antigen 4), LHX1 (LIM homeobox 1), LHX2, and LHX6 in U87 glioma cells in response to ...
Krasnytska Dariia A.   +7 more
doaj   +1 more source

NKL homeobox gene activities in normal and malignant myeloid cells.

open access: yesPLoS ONE, 2019
Recently, we have documented a hematopoietic NKL-code mapping physiological expression patterns of NKL homeobox genes in early hematopoiesis and in lymphopoiesis, which spotlights genes deregulated in lymphoid malignancies.
Stefan Nagel   +8 more
doaj   +1 more source

Identification and characterization of homeobox genes in Eucalyptus

open access: yesGenetics and Molecular Biology, 2005
Homeobox genes encode transcriptional factors, usually involved in molecular control of plant developmental patterns. They can be divided into several classes according to conserved sequences within the homeobox region and the presence of specific ...
Graça Celeste Gomes Rocha   +4 more
doaj   +1 more source

Reconstruction of ancient homeobox gene linkages inferred from a new high-quality assembly of the Hong Kong oyster (Magallana hongkongensis) genome

open access: yesBMC Genomics, 2020
Background Homeobox-containing genes encode crucial transcription factors involved in animal, plant and fungal development, and changes to homeobox genes have been linked to the evolution of novel body plans and morphologies.
Yiqian Li   +7 more
doaj   +1 more source

Analysis of homeobox gene action may reveal novel angiogenic pathways in normal placental vasculature and in clinical pregnancy disorders associated with abnormal placental angiogenesis.

open access: yesFrontiers in Pharmacology, 2014
Homeobox genes are essential for both the development of the blood and lymphatic vascular systems, as well as for their maintenance in the adult. Homeobox genes comprise an important family of transcription factors, which are characterised by a well ...
Padma eMurthi   +5 more
doaj   +1 more source

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