Results 21 to 30 of about 73,647 (262)
Human Homeobox TGIFLX Regulates CDX1, CDX2, and OCT1 Genes Expression in Colorectal Cancer Cell Lines [PDF]
Middle East Journal of Cancer, 2022 Background: Homeodomain transcriptional regulatory proteins, which are encoded by Homeobox (HOX) genes, play critical roles in both normal development and carcinogenesis.
Soroosh Shahryarhesami +3 more
doaj +1 more source
Hepatology, EarlyView., 2022 Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong +9 more
wiley +1 more source
Congenital absence of the left thumb in a surviving twin - a genetic disorder
National Journal of Clinical Anatomy, 2014 Congenital absence of left thumb with deformities of carpal bones in a twin born adult woman is reported here. The subject is the only surviving twin aged forty years reported to the hospital with a complaint of weakness of left hand.
D N Sinha
doaj +1 more source
Isolation of Hox cluster genes from insects reveals an accelerated sequence evolution rate. [PDF]
PLoS ONE, 2012 Among gene families it is the Hox genes and among metazoan animals it is the insects (Hexapoda) that have attracted particular attention for studying the evolution of development.
Heike Hadrys +6 more
doaj +1 more source
F1000Research, 2018 The homeodomain-containing proteins are an important group of transcription factors found in most eukaryotes including animals, plants and fungi. Homeobox genes are responsible for a wide range of critical developmental and physiological processes ...
Wai Hoong Chang, Alvina G. Lai
doaj +1 more source
Establishment of the TALE-code reveals aberrantly activated homeobox gene PBX1 in Hodgkin lymphoma.
PLoS ONE, 2021 Homeobox genes encode transcription factors which regulate basic processes in development and cell differentiation and are grouped into classes and subclasses according to sequence similarities.
Stefan Nagel +4 more
doaj +1 more source
Endocrine Regulations, 2020 Objective. The aim of the present investigation was to study the expression of genes encoding homeobox proteins ZEB2 (zinc finger E-box binding homeobox 2), TGIF1 (TGFB induced factor homeobox 1), SPAG4 (sperm associated antigen 4), LHX1 (LIM homeobox 1),
Tsymbal Dariia O. +8 more
doaj +1 more source
Aberrant activity of NKL homeobox gene NKX3-2 in a T-ALL subset. [PDF]
PLoS ONE, 2018 T-cell acute lymphoblastic leukemia (T-ALL) is a hematopoietic malignancy originating from T-cell progenitors in which differentiation is blocked at early stages.
Stefan Nagel +5 more
doaj +1 more source
NKL homeobox genes in leukemia [PDF]
Leukemia, 2011 NK-like (NKL) homeobox genes code for transcription factors, which can act as key regulators in fundamental cellular processes. NKL genes have been implicated in divergent types of cancer. In this review, we summarize the involvement of NKL genes in cancer and leukemia in particular.
Homminga, Irene +2 more
openaire +4 more sources
NKL homeobox gene activities in hematopoietic stem cells, T-cell development and T-cell leukemia.
PLoS ONE, 2017 T-cell acute lymphoblastic leukemia (T-ALL) cells represent developmentally arrested T-cell progenitors, subsets of which aberrantly express homeobox genes of the NKL subclass, including TLX1, TLX3, NKX2-1, NKX2-5, NKX3-1 and MSX1.
Stefan Nagel +7 more
doaj +1 more source