Results 121 to 130 of about 41,966 (223)

Isolation and chromosomal assignment of human genes encoding cofactor of LIM homeodomain proteins, CLIM1 and CLIM2. [PDF]

, 1999
Cofactors of LIM homeodomain proteins (CLIM) are transcriptional activators that associate with the LIM homeoproteins and coordinate transcription. LIM homeoproteins and CLIMs are involved in a variety of developmental processes.
436429, Ueki, Nobuhide, 関 直彦, 436436, 436437, 齋藤 俊行, Masuho, Yasuhiko, Saito, Toshiyuki, Seki, Naohiko, Ohira, Miki, 436432, Muramatsu, Masa-aki, 436433, 436434, 436435, Yano, Kazuhiro, 436430, 436431   +17 more
core  

Plant evolution: TALES of development. [PDF]

, 2008
TALE homeodomain proteins regulate development in many eukaryotes. Now, Lee et al. (2008) report that two TALE homeodomain proteins control zygote development of the unicellular green alga Chlamydomonas. This implicates TALE gene loss and diversification
Dolan, L, Liam Dolan, Dolan, Liam
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, Volume 20, Issue 7, Page 1835-1856, July 2026.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomain. [PDF]

, 1995
peer reviewedA number of homeodomain proteins have been shown to regulate cellular development by stimulating the transcription of specific target genes.
Kamps, M., Sharma, S., Peers, Bernard, Johnson, T., Montminy, M.   +4 more
core   +1 more source

Deciphering the pathogenicity of three NKX2-1 variants in ultra-severe forms of childhood interstitial lung disease.

PLoS ONE
IntroductionThe transcription factor NK2 homeobox1 (NKX2-1), associated with brain lung thyroid syndrome, regulates the transcription of surfactant proteins, thyroglobulin (TG) and thyroid peroxidase (TPO).
Yohan David Soreze, Tifenn Desroziers-Louedec, Aurore Carré, Farah Diab, Aphrodite Daskalopoulou, Julie Starck, Valérie Nau, Marie Legendre, Sonia-Athina Karabina, Véronique Houdouin, Aurore Coulomb-L'herminé, Camille Louvrier, Nadia Nathan   +12 more
doaj   +1 more source

Genome-wide analysis and expression profiling of zinc finger homeodomain (ZHD) family genes reveal likely roles in organ development and stress responses in tomato

BMC Genomics, 2017
Background Zinc finger homeodomain proteins (ZHD) constitute a plant-specific transcription factor family with a conserved DNA binding homeodomain and a zinc finger motif.
Khadiza Khatun, Ujjal Kumar Nath, Arif Hasan Khan Robin, Jong-In Park, Do-Jin Lee, Min-Bae Kim, Chang Kil Kim, Ki-Byung Lim, Ill Sup Nou, Mi-Young Chung   +9 more
doaj   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

Advanced Science, Volume 13, Issue 37, 3 July 2026.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez   +8 more
wiley   +1 more source

Molecular Acrobats: How CHD Remodelers Shape the Genetic Playground to License Cell Identity

BioEssays, Volume 48, Issue 7, July 2026.
ABSTRACT In eukaryotes, DNA is not a naked repository of genetic information but is tightly wound around histone octamers to form nucleosomes. While this packaging solves the spatial problem of fitting 2 meters of DNA into a microscopic nucleus, it creates a massive accessibility problem for DNA‐templated events, including transcription, replication ...
İsa Özdemir, Sarah J. Hainer
wiley   +1 more source

IDENTIFICATION OF A MOLECULAR SIGNATURE PREDICTIVE OF REFRACTORINESS IN ACUTE MYELOID LEUKEMIA [PDF]

, 2006
Acute Myeloid Leukemia (AML) blast cells are immature committed myeloid cells unable to spontaneously undergo terminal maturation, characterized by heterogeneous sensitivity to natural differentiation inducers. No data are available so far by which infer
TAGLIAFICO, Enrico, BIANCHI, Elisa, Fantoni, Luca, ZANOCCO MARANI, Tommaso, SALATI, Simona, Roncaglia, Enrica, PARENTI, Sandra, Ferrari, Francesco, GEMELLI, Claudia, TENEDINI, Elena, GRANDE, Alexis, FERRARI, Sergio, Tatiana Vignudelli, Tatiana, MONTANARI, Monica, MANFREDINI, Rossella, ZINI, Roberta, BICCIATO, Silvio   +16 more
core  

Functions and interactions of homeodomain proteins during development of the spinal cord [PDF]

, 2006
Das dorsale Rückenmark besteht aus verschiedenen Populationen von Interneuronen, die sensorische Informationen aus der Peripherie verarbeiten und weiterleiten.
Kriks, Sonja
core   +1 more source