Results 61 to 70 of about 1,687,854 (353)

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Dynamic Homeostasis in Packet Switching Networks

, 2014
In this study, we investigate the adaptation and robustness of a packet switching network (PSN), the fundamental architecture of the Internet. We claim that the adaptation introduced by a transmission control protocol (TCP) congestion control mechanism ...
Abe, Hirotake, Ikegami, Takashi, Oka, Mizuki   +2 more
core   +1 more source

The monocyte-macrophage axis in the intestine [PDF]

, 2014
Macrophages are one of the most abundant leucocytes in the intestinal mucosa where they are essential for maintaining homeostasis. However, they are also implicated in the pathogenesis of disorders such as inflammatory bowel disease (IBD), offering ...
Ajami, Allan McI Mowat, Anthony, Auffray, Auffray, Bain, Bain, Bogunovic, Burke, Calum C. Bain, Carlin, Cerovic, Chang, Chen, Chieppa, Chorro, de Schoolmeester, Denning, Denning, Diehl, Dunay, Fogg, Gautier, Geissmann, Glocker, Grainger, Greter, Grimm, Griseri, Guilliams, Hadis, Hapfelmeier, Hashimoto, Hettinger, Hirotani, Hoeffel, Hoshi, Hou, Ingersoll, Jakubzick, Jenkins, Kamada, Kayama, Kim, Kim, Kinnebrew, Kuhn, Kurihara, Lampinen, Landsman, MacDonald, MacDonald, Maheshwari, McDole, Medina-Contreras, Morrison, Mowat, Muller, Murai, Niess, Niess, Pabst, Passlick, Pavli, Persson, Platt, Pull, Rani, Rescigno, Rivollier, Roberts, Rogler, Rugtveit, Rugtveit, Rydström, Satpathy, Satpathy, Schlitzer, Schreiber, Schulthess, Schulz, Schulz, Serbina, Shaw, Siddiqui, Smith, Smythies, Smythies, Smythies, Sunderkotter, Takada, Takeda, Tamoutounour, Tamoutounour, Tarling, Thiesen, Ueda, van Furth, Varol, Varol, Waddell, Wang, Weber, Yona, Ziegler-Heitbrock, Zigmond   +105 more
core   +2 more sources

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Investigating the properties of bio-chemical networks of artificial organisms with opposing behaviours [PDF]

, 2013
Organisms, be it singled-celled organisms or multi-cellular organisms, are constantly faced with opposing objectives requiring different sets of behaviours.
Mokhtar, Maizura
core   +1 more source

USP14 promotes colorectal cancer progression by targeting JNK for stabilization

Cell Death and Disease, 2023
MAPK/JNK signaling is pivotal in carcinogenesis. However, ubiquitin-mediated homeostasis of JNK remains to be verified. Here, with results from RNA sequencing (RNA-seq) and luciferase reporter pathway identification, we show that USP14 orchestrates MAPK ...
Xue-Hua Du, Shao-Bo Ke, Xin-Yi Liang, Jie Gao, Xiao-Xiao Xie, Lin-Zhi Qi, Xue-Yi Liu, Guo-Yuan Xu, Xiao-Dong Zhang, Run-Lei Du, Shang-Ze Li   +10 more
doaj   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Gill transcriptome response to changes in environmental calcium in the green spotted puffer fish [PDF]

, 2010
Background Calcium ion is tightly regulated in body fluids and for euryhaline fish, which are exposed to rapid changes in environmental [Ca2+], homeostasis is especially challenging. The gill is the main organ of active calcium uptake and therefore plays
Canario, Adelino V. M., Matsumura, H., Pinto, Patricia IS, Power, Deborah, Reinhardt, Richard, Terauchi, Ryohei, Thorne, Michael A. S.   +6 more
core   +5 more sources

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Food is our medicine [PDF]

, 2012
The paper describes the role of foods and nutrition in the promotion of human health. The relationship between foods, metabolism, homeostasis and metabolic disorder are briefly described.
Sarmidi, Mohamad Roji
core