Results 41 to 50 of about 2,649,250 (302)

SETD4 Confers Cancer Stem Cell Chemoresistance in Nonsmall Cell Lung Cancer Patients via the Epigenetic Regulation of Cellular Quiescence

open access: yesStem Cells International, 2023
Increasing evidence indicates that quiescent cancer stem cells (CSCs) are a root cause of chemoresistance. SET domain-containing protein 4 (SETD4) epigenetically regulates cell quiescence in breast cancer stem cells (BCSCs), and SETD4-positive BCSCs are ...
Yuehong Wang   +6 more
doaj   +1 more source

Regulating Retinoic Acid Availability during Development and Regeneration: The Role of the CYP26 Enzymes. [PDF]

open access: yes, 2020
This review focuses on the role of the Cytochrome p450 subfamily 26 (CYP26) retinoic acid (RA) degrading enzymes during development and regeneration. Cyp26 enzymes, along with retinoic acid synthesising enzymes, are absolutely required for RA homeostasis
Roberts, C
core   +2 more sources

A cancer stem cell associated gene signature for predicting overall survival of hepatocellular carcinoma

open access: yesFrontiers in Genetics, 2022
Hepatocellular carcinoma (HCC) is the most prevalent type of primary liver cancer characterized by high mortality and morbidity rate. The lack of effective treatments and the high frequency of recurrence lead to poor prognosis of patients with HCC ...
Xin-Yi Liang   +7 more
doaj   +1 more source

The unbearable lightness of bone marrow homeostasis [PDF]

open access: yes, 2015
The anatomical and functional dimensions of bone marrow topography have been at the forefront of modern bone and immunological research for many years and remain a source of complexity and perplexity due to the multitude of microhabitats within this ...
AGAS, DIMITRIOS   +3 more
core   +1 more source

Energy Homeostasis of the Artificial Bladder in Experimental Conditions [PDF]

open access: yes, 2018
Patients with Malignant neoplasms of the bladder or severe anatomical and functional bladder abnormalities are the candidates for cystectomy and orthotopic urine diversion.
Dekhtiar, Y. (Yriy)   +3 more
core  

Cysteine homeostasis.

open access: yes, 2015
of essential biomolecules, such as vitamins, cofactors, antioxidants and many defence compounds, that are formed in response to adverse environmental conditions in which the sulfur moiety is the functional group. Sulfate is transported inside the plant, reduced to sulfide and incorporated into O-acetylserine (OAS) to form cysteine.
García, Irene   +2 more
openaire   +2 more sources

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Food is our medicine [PDF]

open access: yes, 2012
The paper describes the role of foods and nutrition in the promotion of human health. The relationship between foods, metabolism, homeostasis and metabolic disorder are briefly described.
Sarmidi, Mohamad Roji
core  

Bone homeostasis [PDF]

open access: yesProceedings of the National Academy of Sciences, 1998
The functions of bone(s) are (i) mechanical support of soft tissues, (ii) levers for muscle action, (iii) protection of the central nervous system, (iv) release of calcium and other ions for the maintenance of a constant ionic environment in the extracellular fluid, and (v) housing and support of hemopoiesis.
openaire   +2 more sources

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