Results 21 to 30 of about 1,927,335 (268)

The Zinc Finger Transcription Factor Fts2 Represses the Yeast-to-Filament Transition in the Dimorphic Yeast Yarrowia lipolytica

mSphere, 2022
The yeast-to-filament transition is an important cellular response to environmental stimulations in dimorphic fungi. In addition to activators, there are repressors in the cells to prevent filament formation, which is important to keep the cells in the ...
Jia-Wen Chen, Yi-Sheng Mao, Lv-Qiao Yan, Xiang-Dong Gao   +3 more
doaj   +1 more source

Homeostasis Patterns

SIAM Journal on Applied Dynamical Systems
36 pages, 10 figures, 2 ...
William Duncan, Fernando Antoneli, Janet Best, Martin Golubitsky, Jiaxin Jin, H. Frederik Nijhout, Mike Reed, Ian Stewart 0001   +7 more
openaire   +3 more sources

Homeostasis and Narcolepsy [PDF]

Sleep, 1994
Narcolepsy is characterized by irresistible daytime sleep episodes and cataplectic attacks. Because of the finding of an ultradian rhythmicity of slow-wave sleep in narcolepsy, an alteration of nonrapid eye movement sleep homeostatic regulation has been hypothesized to explain the impairment of the sleep-wakefulness cycle. This hypothesis was tested by
A, Besset, M, Tafti, L, Nobile, M, Billiard   +3 more
openaire   +2 more sources

Long‐Term Administration of Eicosapentaenoic Acid Improves Post–Myocardial Infarction Cardiac Remodeling in Mice by Regulating Macrophage Polarization

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundConsumption of n‐3 fatty acids reduces the incidence of cardiovascular mortality in populations that consume diets rich in fish oil. Eicosapentaenoic acid (EPA) is an n‐3 fatty acid known to reduce the frequency of nonfatal coronary events ...
Masayuki Takamura, Keisuke Kurokawa, Hiroshi Ootsuji, Oto Inoue, Hikari Okada, Ayano Nomura, Shuichi Kaneko, Soichiro Usui   +7 more
doaj   +1 more source

Genome-Wide Insight into Profound Effect of Carbon Catabolite Repressor (Cre1) on the Insect-Pathogenic Lifecycle of Beauveriabassiana

Journal of Fungi, 2021
Carbon catabolite repression (CCR) is critical for the preferential utilization of glucose derived from environmental carbon sources and regulated by carbon catabolite repressor A (Cre1/CreA) in filamentous fungi.
Rehab Abdelmonem Mohamed, Kang Ren, Ya-Ni Mou, Sheng-Hua Ying, Ming-Guang Feng   +4 more
doaj   +1 more source

The plant alkaloid tetrandrine inhibits metastasis via autophagy-dependent Wnt/β-catenin and metastatic tumor antigen 1 signaling in human liver cancer cells

Journal of Experimental & Clinical Cancer Research, 2018
Background Tetrandrine is a bisbenzylisoquinoline alkaloid isolated from the Chinese medicinal herb Stephania tetrandra S. Moore. We previously demonstrated that tetrandrine exhibits potent antitumor effects in many types of cancer cells.
Zhenxing Zhang, Ting Liu, Man Yu, Kangdi Li, Wenhua Li   +4 more
doaj   +1 more source

SETD4 Confers Cancer Stem Cell Chemoresistance in Nonsmall Cell Lung Cancer Patients via the Epigenetic Regulation of Cellular Quiescence

Stem Cells International, 2023
Increasing evidence indicates that quiescent cancer stem cells (CSCs) are a root cause of chemoresistance. SET domain-containing protein 4 (SETD4) epigenetically regulates cell quiescence in breast cancer stem cells (BCSCs), and SETD4-positive BCSCs are ...
Yuehong Wang, Yuman Yu, Weijun Yang, Linying Wu, Yaoshun Yang, Qianyun Lu, Jianying Zhou   +6 more
doaj   +1 more source

Conserved and Noncanonical Activities of Two Histone H3K36 Methyltransferases Required for Insect-Pathogenic Lifestyle of Beauveria bassiana

Journal of Fungi, 2021
Set2 and Ash1 are histone methyltransferases (KMTs) in the KMT3 family normally used to catalyze methylation of histone H3K36 (H3K36me) but remain unexplored in fungal insect pathogens.
Kang Ren, Ya-Ni Mou, Sheng-Hua Ying, Ming-Guang Feng   +3 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Evidence and Impacts of Nanoplastic Accumulation on Crop Grains

Advanced Science, 2022
Nanoplastics are emerging pollutants of global concern. Agricultural soil is becoming a primary sink for nanoplastics generated from plastic debris. The uptake and accumulation of nanoplastics by crops contaminate the food chain and pose unexpected risks
Meng Jiang, Binqiang Wang, Rui Ye, Ning Yu, Zhenming Xie, Yuejin Hua, Ruhong Zhou, Bing Tian, Shang Dai   +8 more
doaj   +1 more source