Results 11 to 20 of about 2,139,288 (317)

Osmotic Homeostasis [PDF]

open access: yesClinical Journal of the American Society of Nephrology, 2015
Alterations in water homeostasis can disturb cell size and function. Although most cells can internally regulate cell volume in response to osmolar stress, neurons are particularly at risk given a combination of complex cell function and space restriction within the calvarium. Thus, regulating water balance is fundamental to survival.
John, Danziger, Mark L, Zeidel
openaire   +2 more sources

Disruption to homeostasis [PDF]

open access: yesHealth Care for Women International, 2020
There are many things that cause disruptions to social order including natural disasters and pandemics. Natural disasters and pandemics tend to shake up all social institutions.
Eleanor, Krassen Covan   +1 more
openaire   +2 more sources

Adaptive cell invasion maintains lateral line organ homeostasis in response to environmental changes

open access: yes, 2021
Mammalian inner ear and fish lateral line sensory hair cells (HCs) detect fluid motion to transduce environmental signals. Actively maintained ionic homeostasis of the mammalian inner ear endolymph is essential for HC function.
Romero Carvajal, Marco Andrés
core   +1 more source

Characterization of Hsp17, a Novel Small Heat Shock Protein, in Sphingomonas melonis TY under Heat Stress

open access: yesMicrobiology Spectrum, 2023
Bacteria are constantly exposed to a variety of environmental stresses. Temperature is considered one of the most important environmental factors affecting microbial growth and survival.
Yihan Wang   +5 more
doaj   +1 more source

An optimized base editor with efficient C-to-T base editing in zebrafish

open access: yesBMC Biology, 2020
Background Zebrafish is a model organism widely used for the understanding of gene function, including the fundamental basis of human disease, enabled by the presence in its genome of a high number of orthologs to human genes.
Yu Zhao   +4 more
doaj   +1 more source

Epithelial Homeostasis [PDF]

open access: yesCurrent Biology, 2014
Epithelia form intelligent, dynamic barriers between the external environment and an organism's interior. Intercellular cadherin-based adhesions adapt and respond to mechanical forces and cell density, while tight junctions flexibly control diffusion both within the plasma membrane and between adjacent cells. Epithelial integrity and homeostasis are of
Macara, Ian G.   +4 more
openaire   +2 more sources

Mining genomes of marine cyanobacteria for elements of zinc homeostasis [PDF]

open access: yes, 2012
Zinc is a recognized essential element for the majority of organisms, and is indispensable for the correct function of hundreds of enzymes and thousands of regulatory proteins.
Schmid, Ralf   +23 more
core   +1 more source

Combination therapy with protein kinase inhibitor H89 and Tetrandrine elicits enhanced synergistic antitumor efficacy

open access: yesJournal of Experimental & Clinical Cancer Research, 2018
Background Tetrandrine, a bisbenzylisoquinoline alkaloid that was isolated from the medicinal plant Stephania tetrandrine S. Moore, was recently identified as a novel chemotherapy drug. Tetrandrine exhibited a potential antitumor effect on multiple types
Man Yu   +4 more
doaj   +1 more source

Competitive oxidation and ubiquitylation on the evolutionarily conserved cysteine confer tissue-specific stabilization of Insig-2

open access: yesNature Communications, 2020
The protein Insig-2 negatively regulates lipid biosynthesis and is short-lived in liver cells but stable in muscle cells. Here, the authors show that in muscle cells producing reactive oxygen species, there is increased oxidation compared to ...
Zhang-Sen Zhou   +11 more
doaj   +1 more source

A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia

open access: yesNature Communications, 2023
Glial cells have been proposed as a source of neural progenitors, but the mechanisms underpinning the neurogenic potential of adult glia are not known.
Anna Laddach   +14 more
doaj   +1 more source

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