Results 11 to 20 of about 1,927,335 (268)
Clinical Journal of the American Society of Nephrology, 2015 Alterations in water homeostasis can disturb cell size and function. Although most cells can internally regulate cell volume in response to osmolar stress, neurons are particularly at risk given a combination of complex cell function and space restriction within the calvarium. Thus, regulating water balance is fundamental to survival.
John, Danziger, Mark L, Zeidel
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Disruption to homeostasis [PDF]
Health Care for Women International, 2020 There are many things that cause disruptions to social order including natural disasters and pandemics. Natural disasters and pandemics tend to shake up all social institutions.
Eleanor, Krassen Covan +1 more
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Current Biology, 2014 Epithelia form intelligent, dynamic barriers between the external environment and an organism's interior. Intercellular cadherin-based adhesions adapt and respond to mechanical forces and cell density, while tight junctions flexibly control diffusion both within the plasma membrane and between adjacent cells. Epithelial integrity and homeostasis are of
Macara, Ian G. +4 more
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Telomerase regulation by the long non-coding RNA H19 in human acute promyelocytic leukemia cells
Molecular Cancer, 2018 Background Since tumor growth requires reactivation of telomerase (hTERT), this enzyme is a challenging target for drug development. Therefore, it is of great interest to identify telomerase expression and activity regulators.
Joëlle El Hajj +6 more
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Journal of Experimental & Clinical Cancer Research, 2018 Background Tetrandrine, a bisbenzylisoquinoline alkaloid that was isolated from the medicinal plant Stephania tetrandrine S. Moore, was recently identified as a novel chemotherapy drug. Tetrandrine exhibited a potential antitumor effect on multiple types
Man Yu +4 more
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An optimized base editor with efficient C-to-T base editing in zebrafish
BMC Biology, 2020 Background Zebrafish is a model organism widely used for the understanding of gene function, including the fundamental basis of human disease, enabled by the presence in its genome of a high number of orthologs to human genes.
Yu Zhao +4 more
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Nature Communications, 2020 The protein Insig-2 negatively regulates lipid biosynthesis and is short-lived in liver cells but stable in muscle cells. Here, the authors show that in muscle cells producing reactive oxygen species, there is increased oxidation compared to ...
Zhang-Sen Zhou +11 more
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A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia
Nature Communications, 2023 Glial cells have been proposed as a source of neural progenitors, but the mechanisms underpinning the neurogenic potential of adult glia are not known.
Anna Laddach +14 more
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Microbiology Spectrum, 2023 As a crucial growth factor, thiamine can regulate functional microbial communities; however, our current understanding of its effect on bioremediation is lacking. Using metatranscriptome and 16S rRNA gene sequencing, we explored the mechanism of response
Hui Huang +4 more
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Frontiers in Microbiology, 2019 DNA methylation serves as a vital component of restriction-modification (R-M) systems in bacteria, where it plays a crucial role in defense against foreign DNA.
Shengjie Li +11 more
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