Results 41 to 50 of about 34,206 (311)
“You Are My Streams”: Ronsard as French Homer [PDF]
This article examines the origins and meaning of the metaphor of the Ocean and Streams, by which Pierre de Ronsard was compared to Homer. Dating back to Quintilian, the metaphor had become a topos by the mid-16th century, thanks to the admirers of his ...
Irina K. Staf
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Highlights • Identifying glutamatergic synapses is important for tracing synaptic circuits.• Most proteins at glutamatergic synapses are masked by tissue fixation.• Homer can reveal glutamatergic synapses without the need for antigen retrieval.
M. Gutierrez-Mecinas +5 more
semanticscholar +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Ischemic and traumatic insults to the central nervous system account for most serious acute and fatal brain injuries and are usually characterized by primary and secondary damage.
Xiu-Quan Wu, Ning Su, Zhou Fei, Fei Fei
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins.
Shank is a recently described family of postsynaptic proteins that function as part of the NMDA receptor-associated PSD-95 complex (Naisbitt et al., 1999 [this issue of Neuron]). Here, we report that Shank proteins also bind to Homer. Homer proteins form
J. Tu +12 more
semanticscholar +1 more source
Studi Kelayakan Pembangkit Listrik Tenaga Hybrid Surya Bayu di Kota Bandung
ABSTRAK Pada penelitian ini dilakukan analisis studi kelayakan potensi pembangkit listrik tenaga hybrid dengan sumber energi terbarukan surya dan bayu untuk skala rumah tangga di daerah kota Bandung.
FEBRIAN HADIATNA +2 more
doaj +1 more source

