Results 51 to 60 of about 34,206 (311)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Crossing Dreams: the Neglected Dreams of the Homeric Poems and the Poetics of Epic [PDF]
Revista de Istorie și Teorie LiterarăThis article explores the status of dreams in Homer’s Iliad and Odyssey.Dreams serve many different purposes in the epic; they also continuously elude all attempts to define or categorize them in a single, conclusive way.
Dorin Garofeanu
doaj +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Annals of Language and Literature, 2019 Andrew Ford here addresses, in a manner both engaging and richly informed, the perennial questions of what poetry is, how it came to be, and what it is for. Focusing on the critical moment in Western literature when the heroic tales of the Greek oral tradition began to be preserved in writing, he examines these questions in the light of Homeric poetry.
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Open Journal of Humanities, 2023 This paper examines Iliad I 225-244 and XXIV 486-506, two passages at the beginning and at the end respectively of Achilles’ narrative arc. This work aims at showing the way in which traditional epic techniques (enjambement, similitude, interrelation ...
Elisabetta Pitotto
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Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Diagnostyka, 2022 One of the pillars for the development of isolated communities is electricity, however the implementation of conventional networks is limited as a result of the difficulties of the terrain. This paper aims to analyze the technical-economic feasibility of
Lata-Carlos Juan +1 more
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PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source