Results 141 to 150 of about 360,376 (378)

What is the Place of Beef in a Healthful Sustainable Homo sapiens Diet? [PDF]

, 2022
Mary Murimi
openalex   +1 more source

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

Advanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang, Xiangheng Cai, Mengqi Li, Xue Liu, Junhui Xue, Ye Liu, Ding Ai, Xinyang Hu   +7 more
wiley   +1 more source

Did climate change make Homo sapiens innovative, and if yes, how? Debated perspectives on the African Pleistocene record

Quaternary Science Advances
Our enhanced capacity to innovate is a key feature that sets Homo sapiens apart as a species. The Middle Stone Age archaeological record of Pleistocene Africa documents the emergence and elaboration of this capacity, and its relationship to changes in ...
Jayne Wilkins, Benjamin J. Schoville
doaj   +1 more source

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

Advanced Science, EarlyView.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu, Yan Xu, Lang Qin, Zemin Ling, Yingjie Mai, Xiong Tian Guo, Jiajia Chen, Leping Yan, Lin Wang, Liming Bian, Fuxin Wei   +10 more
wiley   +1 more source

Genotypes and Phenotypes of Patients With TSPEAR‐Related Disorder: Evidence of a Predominant Dental Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT TSPEAR (chr. 21q22.3) encodes a protein involved in tooth development and is predominantly expressed in the enamel knot. Biallelic loss of function variants in TSPEAR cause ectodermal dysplasia, tooth agenesis and sensorineural hearing loss. However, the role of TSPEAR in auditory processes is unclear.
Debora Vergani, Lucia Tiberi, Annarita Giliberti, Elia Dirupo, Laila Zaroili, Francesco Brancati, Michela Brena, Stefano Caraffi, Chiara De Luca, Livia Garavelli, Anna Virginia Gulino, Milena Mariani, Marzia Pollazzon, Angelo Selicorni, Samuela Landini, Ilaria Sani, Rosangela Artuso, Angela Peron   +17 more
wiley   +1 more source

The rhizome of Reclinomonas americana, Homo sapiens, Pediculus humanus and Saccharomyces cerevisiae mitochondria [PDF]

, 2011
Kalliopi Georgiades, Didier Raoult
openalex   +1 more source

Identification of ferroptosis‐related genes involved in chronic obstructive pulmonary disease based on bioinformatics analysis

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Green part represents the bioinformatics analysis approach. Yellow part represents the ideas of animal experiment. Abstract Background Chronic obstructive pulmonary disease (COPD) is a type of chronic respiratory disease.
Xuejing Luan, Jinghui Xie, Lu Zhang, Xiao Ma, Lichangtian Jiao, Jie Zhu   +5 more
wiley   +1 more source

ОСТРОВА В ОКЕАНЕ ИЛИ ОКЕАН ОСТРОВОВ: КАМЕННЫЙ ВЕК ЮГО-ВОСТОЧНОЙ АЗИИ

Теория и практика археологических исследований
Данные археологии и физической антропологии убедительно свидетельствуют о том, что все этапы появления в островной части Юго-Восточной Азии ранних представителей Homo и последующего освоения этой территории Homo sapiens связаны со спецификой ...
А.В. Табарев
doaj   +1 more source

A criança do Lapedo e as origens do homem moderno na Península Ibérica [PDF]

, 2005
Durante as três últimas décadas do século XX, o debate sobre as origens da humanidade actual girou em torno de duas posições fortemente polarizadas (Fig. 1).
Zilhão, João
core  

Analysis of salt-bridges in prolyl oligopeptidase from Pyrococcus furiosus and Homo sapiens [PDF]

, 2019
Amal Kumar Bandyopadhyay, Rifat Nawaz Ul Islam, Debanjan Mitra, Sahini Banerjee, Arunava Goswami   +4 more
openalex   +1 more source