Results 41 to 50 of about 848,819 (301)
Preparation of Reference Materials GBW10010a for Rice Component and Data Characteristics
BACKGROUND With the increased attention paid for the construction of ecological civilization, a comprehensive survey of natural resources is imperative, and new requirements for biological reference materials have also been put forward.
YANG Rong +4 more
doaj +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Homogeneity of the Temperature Data Series from ERA5 and MERRA2 and Temperature Trends
The stratosphere and its dynamics are a very important part of atmospheric circulation. We need to analyze its climatology, as well as long-term trends. A long-term trend study needs homogenous datasets without significant artificial discontinuities. The
Michal Kozubek +2 more
doaj +1 more source
Retrospective analysis of quality data of different blood components in Chongqing
Objective To provide reference for formulating relatively unified quality control strategies and meeting the requirements of homogenization construction of blood banks across Chongqing area by retrospectively analyzing sampling results of different blood
Zhanpeng LUO +6 more
doaj +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
An Evaluation of Multiple Imputation for Meta-Analytic Structural Equation Modeling [PDF]
A simulation study was used to evaluate multiple imputation (MI) to handle MCAR correlations in the first step of meta-analytic structural equation modeling: the synthesis of the correlation matrix and the test of homogeneity.
Beretvas, S. Natasha, Furlow, Carolyn F.
core +2 more sources
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source

