Results 71 to 80 of about 848,819 (301)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Understanding Price Variation Across Stores and Supermarket Chains: Some Implications for CPI Aggregation Methods [PDF]

The empirical literature on price indices consistently finds that aggregation methods have a considerable impact, particularly when scanner data are used.
Kevin J. Fox, Lorraine Ivancic
core  

A One-Sample Test for Normality with Kernel Methods [PDF]

, 2015
We propose a new one-sample test for normality in a Reproducing Kernel Hilbert Space (RKHS). Namely, we test the null-hypothesis of belonging to a given family of Gaussian distributions.
Celisse, Alain, Kellner, Jérémie
core   +2 more sources

Effect of a preliminary test of homogeneity of stratum-specific odds ratios on their confidence intervals

, 2012
Consider a case-control study in which the aim is to assess the effect of a factor on disease occurrence. We suppose that this factor is dichotomous. Also suppose that the data consists of two strata, each stratum summarized by a two-by-two table.
Kabaila, Paul, Tissera, Dilshani
core   +1 more source

Earthquake modelling at the country level using aggregated spatio-temporal point processes [PDF]

, 2011
The goal of this paper is to derive a hazard map for earthquake occurrences in Pakistan from a catalogue that contains spatial coordinates of shallow earthquakes of magnitude 4.5 or larger aggregated over calendar years.
Lieshout, M.N.M., Stein, A.
core   +7 more sources

Weighing temporal fluctuations of drought features in Rwanda through the implementation of the standardized precipitation evapotranspiration index and standardized precipitation index

Environmental Research Communications
Climate change poses significant challenges globally, affecting weather patterns and leading to more frequent and severe extreme events such as droughts.
Kazora Jonah, Zhu Weijun, Kyaw Oo Than, Temesgen Gebremariam Asfaw, Emmanuel Adu Gyamfi Kedjanyi, Abraham Okrah, Akimana Diane, Mathieu Mbati Mugunga   +7 more
doaj   +1 more source

The Influence of Firm Ecological Recruitment Advertisements On Organizational Attractiveness and Career Choices: An Experimental Research

Gadjah Mada International Journal of Business, 2004
This present study investigates college students’ interest to a green company and intention to work for the company. This study also investigates how much salary they are willing to receive to work for the company. The results of the study show construct
Pracoyo Budi Jatmiko
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Estudo de homogeneidade de lote de material silício metálico candidato a material de referência Homogeneity testing of a lot of silicon metal prepared as a reference material

Química Nova, 2005
From the perspective of the uncertainties in chemical measurements all uncertainty sources should be part of the uncertainty of the reference material.
Queenie Siu Hang Chui, Celia Omine Iamashita, João Marcos de Almeida Bispo   +2 more
doaj   +1 more source