Results 21 to 30 of about 1,306,827 (384)

Rad54: the Swiss Army knife of homologous recombination? [PDF]

, 2006
Homologous recombination (HR) is a ubiquitous cellular pathway that mediates transfer of genetic information between homologous or near homologous (homeologous) DNA sequences. During meiosis it ensures proper chromosome segregation in the first division.
Heyer, Wolf-Dietrich, Li, Xuan, Rolfsmeier, Michael, Zhang, Xiao-Ping   +3 more
core   +2 more sources

Non-homologous DNA end joining and alternative pathways to double-strand break repair

Nature reviews. Molecular cell biology, 2017
DNA double-strand breaks (DSBs) are the most dangerous type of DNA damage because they can result in the loss of large chromosomal regions. In all mammalian cells, DSBs that occur throughout the cell cycle are repaired predominantly by the non-homologous
Howard H. Y. Chang, Nicholas R. Pannunzio, N. Adachi, M. Lieber   +3 more
semanticscholar   +1 more source

An interpretation of E n -homology as functor homology [PDF]

Mathematische Zeitschrift, 2010
We prove that E_n-homology of non-unital commutative algebras can be described as functor homology when one considers functors from a certain category of planar trees with n levels. For different n these homology theories are connected by natural maps, ranging from Hochschild homology and its higher order versions to Gamma homology.
Livernet, Muriel, Richter, Birgit
openaire   +2 more sources

Double-strand break repair and homologous recombination in Schizosaccharomyces pombe [PDF]

, 2006
In recent years our understanding of double strand break repair and homologous recombination in Schizosaccharomyces pombe has increased significantly, and the identification of novel pathways and genes with homologues in higher eukaryotes has increased ...
Ahmad, Ahmad, Ahn, Ahnesorg, Akamatsu, Assenmacher, Baumann, Boddy, Boddy, Bonatto, Bransteitter, Buck, Callebaut, Caspari, Catlett, Cervantes, Chahwan, Cheok, Connelly, Cooper, Doe, Doe, Doe, Doe, Dudasova, Farah, Farah, Ferreira, Ferreira, Fukushima, Gaillard, Goedecke, Goodwin, Grishchuk, Haber, Hartsuiker, Hefferin, Jang, Jung, Khasanov, Khasanov, Kibe, Kim, Kim, Krogh, Lambert, Laursen, Macris, Maftahi, Maftahi, Manolis, Marchetti, Martin, McGlynn, Moore, Morishita, Muris, Muris, Muris, Murray, Nakada, Nakamura, Oakley, Ono, Osman, Osman, Osman, Ostermann, Paques, Parker, Prudden, Sauvageau, Schmidt, Segurado, Shinohara, Smith, Steiner, Stewart, Sung, Suto, Szankasi, Szostak, Tarsounas, Tavassoli, Thacker, Tomita, Tomita, Tsutsui, Tsutsui, Ueno, van den Bosch, van den Bosch, Virgin, Virgin, Wang, Weterings, Whitby, Whitby, Wilson, Win, Win, You, Young   +102 more
core   +2 more sources

The C/EBP Homologous Protein (CHOP) Transcription Factor Functions in Endoplasmic Reticulum Stress-Induced Apoptosis and Microbial Infection

Frontiers in Immunology, 2019
Apoptosis is a form of cell death by which the body maintains the homeostasis of the internal environment. Apoptosis is an initiative cell death process that is controlled by genes and is mainly divided into endogenous pathways (mitochondrial pathway ...
Hai Hu, M. Tian, C. Ding, Shengqing Yu
semanticscholar   +1 more source

Homologous Recombination Deficiencies and Hereditary Tumors

International Journal of Molecular Sciences, 2021
Homologous recombination (HR) is a vital process for repairing DNA double-strand breaks. Germline variants in the HR pathway, comprising at least 10 genes, such as BRCA1, BRCA2, ATM, BARD1, BRIP1, CHEK2, NBS1(NBN), PALB2, RAD51C, and RAD51D, lead to ...
H. Yamamoto, Akira Hirasawa
semanticscholar   +1 more source

Homology operations in symmetric homology [PDF]

Homology, Homotopy and Applications, 2014
The symmetric homology of a unital associative algebra $A$ over a commutative ground ring $k$, denoted $HS_*(A)$, is defined using derived functors and the symmetric bar construction of Fiedorowicz. In this paper we show that $HS_*(A)$ admits homology operations and a Pontryagin product structure making $HS_*(A)$ an associative commutative graded ...
openaire   +2 more sources

Nitrogenase and homologs [PDF]

JBIC Journal of Biological Inorganic Chemistry, 2014
Nitrogenase catalyzes biological nitrogen fixation, a key step in the global nitrogen cycle. Three homologous nitrogenases have been identified to date, along with several structural and/or functional homologs of this enzyme that are involved in nitrogenase assembly, bacteriochlorophyll biosynthesis and methanogenic process, respectively.
Hu, Yilin, Ribbe, Markus W
openaire   +4 more sources

PALB2 self-interaction controls homologous recombination. [PDF]

, 2012
PALB2 is essential for BRCA2 anchorage to nuclear structures and for homologous recombinational repair of DNA double-strand breaks. Here, we report that the N-terminal coiled-coil motif of PALB2 regulates its self-association and homologous recombination.
Buisson, Rémi, Masson, Jean-Yves
core   +1 more source

Dez anos de experiência com a substituição da valva aórtica com homoenxertos valvares aórticos implantados pela técnica da substituição total da raiz Ten years experience of aortic valve replacement with aortic homograft root replacement

Brazilian Journal of Cardiovascular Surgery, 2006
OBJETIVO: Avaliar os resultados imediatos e tardios de 10 anos da substituição da valva aórtica por homoenxertos valvares aórticos implantados pela técnica de substituição total da raiz, e identificar eventuais fatores de risco correlacionados com a ...
Francisco Costa, Daniele de Fátima Fornazari, Camila Naomi Matsuda, Rafael de Almeida Torres, Evandro Sardetto, Andreia Dumsch de Aragon Ferreira, Claudinei Colatusso, Carlos Henrique Gori Gomes, Marise Brenner Affonso da Costa   +8 more
doaj   +1 more source