Results 21 to 30 of about 319,606 (332)
Distance between homologous chromosomes results from chromosome positioning constraints [PDF]
The organization of chromosomes is important for various biological processes and is involved in the formation of rearrangements often observed in cancer. In mammals, chromosomes are organized in territories that are radially positioned in the nucleus. However, it remains unclear whether chromosomes are organized relative to each other.
Heride, Claire +7 more
openaire +4 more sources
Polyploid organisms provide additional opportunities to study meiosis in a more complex context since more than two potential homologous chromosomes are available.
Pablo Parra-Nunez +2 more
doaj +1 more source
PAR-TERRA directs homologous sex chromosome pairing [PDF]
In mammals, homologous chromosomes rarely pair outside meiosis. One exception is the X chromosome, which transiently pairs during X-chromosome inactivation (XCI). How two chromosomes find each other in 3D space is not known. Here, we reveal a required interaction between the X-inactivation center (Xic) and the telomere in mouse embryonic stem (ES ...
Hsueh‐Ping Chu +7 more
openalex +5 more sources
Meiotic Chromosome Dynamics in Zebrafish
Recent studies in zebrafish have revealed key features of meiotic chromosome dynamics, including clustering of telomeres in the bouquet configuration, biogenesis of chromosome axis structures, and the assembly and disassembly of the synaptonemal complex ...
Yukiko Imai +5 more
doaj +1 more source
A recurrent translocation is mediated by homologous recombination between HERV-H elements
Background Chromosome rearrangements are caused by many mutational mechanisms; of these, recurrent rearrangements can be particularly informative for teasing apart DNA sequence-specific factors.
Hermetz Karen E +3 more
doaj +1 more source
Double in situ hybridization in combination with digital image analysis: A new approach to study interphase chromosome topography [PDF]
Double in situ hybridization with mercurated and biotinylated chromosome specific DNA probes in combination with digital image analysis provides a new approach to compare the distribution of homologous and nonhomologous chromosome targets within ...
Cremer, Christoph +9 more
core +1 more source
During meiosis, the chromosome axes and synaptonemal complex mediate chromosome pairing and homologous recombination to maintain genomic stability and accurate chromosome segregation.
Chiara Di Dio +3 more
doaj +1 more source
The Origin of a New Sex Chromosome by Introgression between Two Stickleback Fishes. [PDF]
Introgression is increasingly recognized as a source of genetic diversity that fuels adaptation. Its role in the evolution of sex chromosomes, however, is not well known. Here, we confirm the hypothesis that the Y chromosome in the ninespine stickleback,
Abbott +78 more
core +1 more source
Direct and indirect control of the initiation of meiotic recombination by DNA damage checkpoint mechanisms in budding yeast [PDF]
Meiotic recombination plays an essential role in the proper segregation of chromosomes at meiosis I in many sexually reproducing organisms. Meiotic recombination is initiated by the scheduled formation of genome-wide DNA double-strand breaks (DSBs).
AJ MacQueen +40 more
core +7 more sources
Background Genome sequencing technologies have been improved at an exponential pace but precise chromosome-scale genome assembly still remains a great challenge. The draft genome of cultivated G.
Javaria Ashraf +10 more
doaj +1 more source

