Transcriptional and posttranscriptional regulation of human androgen receptor expression by androgen. [PDF]
, 1993 Autoregulation is a control mechanism common to several proteins of the steroid/thyroid hormone receptor superfamily. In this work the effect of androgens and antiandrogens on the expression of the human androgen receptor (hAR) in prostate and breast ...
Blasschke, Dorothea +4 more
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Information Transfer in Gonadotropin-Releasing Hormone (GnRH) Signaling:Extracellular Signal-Regulated Kinase (ERK)-Mediated Feedback Loops Control Hormone Sensing [PDF]
, 2015 Cell signaling pathways are noisy communication channels, and statistical measures derived from information theory can be used to quantify the information they transfer.
Bowsher, Clive +8 more
core +3 more sources
Endocrinology and the brain: Corticotropin-Releasing Hormone signaling [PDF]
, 2017 Corticotropin-releasing hormone (CRH) is a key player of basal and stress activated responses in the hypothalamic-pituitary-adrenal axis (HPA) and in extrahypothalamic circuits, where it functions as a neuromodulator to orchestrate humoral and behavioral
Armando, Natalia Giannina +3 more
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Conformational variability of the glycine receptor M2 domain in response to activation by different agonists [PDF]
, 2007 Models describing the structural changes mediating cys-loop receptor activation generally give little attention to the possibility that different agonists may promote activation via distinct M2 pore-lining domain structural rearrangements.
Akabas +30 more
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Differential heterologous and homologous desensitization of two receptors for ATP (P2y purinoceptors and nucleotide receptors) coexisting on endothelial cells. [PDF]
, 1994 Graeme Wilkinson +2 more
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Journal of Biological Chemistry, 1988 Activation of phosphoinositide breakdown is thought to be an important signaling pathway involved in the mitogenic effects of alpha-thrombin in Chinese hamster lung fibroblasts. We have previously shown that the initial strong stimulation of inositol phosphate formation induced by thrombin in quiescent hamster cells (CCL39 line) is rapidly attenuated ...
S, Paris, I, Magnaldo, J, Pouysségur
openaire +2 more sources
Down‐regulation of bombesin binding to guinea‐pig pancreatic acinar cells during homologous desensitization [PDF]
, 1994 Lars Sjödin, Erik Gylfe
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Phosphorylation/dephosphorylation of the beta-adrenergic receptor regulates its functional coupling to adenylate cyclase and subcellular distribution. [PDF]
, 1986 Prolonged exposure of cells or tissues to drugs or hormones such as catecholamines leads to a state of refractoriness to further stimulation by that agent, known as homologous desensitization.
Benovic, JL +4 more
core
Regulation of Corticotropin‐Releasing Factor Receptor Function in Human Y‐79 Retinoblastoma Cells: Rapid and Reversible Homologous Desensitization but Prolonged Recovery [PDF]
, 1997 Richard L. Hauger +4 more
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Tumor-associated EGFR over-expression specifically activates Stat3 and Smad7 resulting in desensitization of TGF-β signaling [PDF]
, 2008 Transforming Growth Factor-[beta] (TGF-[beta]) and Epidermal Growth Factor (EGF) signaling pathways are both independently implicated as key regulators in tumor formation and progression.
Bo Wang +3 more
core +1 more source