The intrinsic ability of double-stranded DNA to carry out D-loop and R-loop formation
Computational and Structural Biotechnology Journal, 2020 Double-stranded (ds)DNA, not dsRNA, has an ability to form a homologous complex with single-stranded (ss)DNA or ssRNA of homologous sequence. D-loops and homologous triplexes are homologous complexes formed with ssDNA by RecA/Rad51-family homologous ...
Takehiko Shibata +2 more
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Modeling cell biological features of meiotic chromosome pairing to study interlock resolution.
PLoS Computational Biology, 2022 During meiosis, homologous chromosomes become associated side by side in a process known as homologous chromosome pairing. Pairing requires long range chromosome motion through a nucleus that is full of other chromosomes.
Erik J Navarro +2 more
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Competition of Parental Genomes in Plant Hybrids
Frontiers in Plant Science, 2020 Interspecific hybridization represents one of the main mechanisms of plant speciation. Merging of two genomes from different subspecies, species, or even genera is frequently accompanied by whole-genome duplication (WGD).
Marek Glombik +4 more
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Synaptonemal complex components persist at centromeres and are required for homologous centromere pairing in mouse spermatocytes. [PDF]
PLoS Genetics, 2012 Recent studies in simple model organisms have shown that centromere pairing is important for ensuring high-fidelity meiotic chromosome segregation. However, this process and the mechanisms regulating it in higher eukaryotes are unknown.
C Gaston Bisig +6 more
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Meiotic Nuclear Oscillations Are Necessary to Avoid Excessive Chromosome Associations
Cell Reports, 2016 Pairing of homologous chromosomes is a crucial step in meiosis, which in fission yeast depends on nuclear oscillations. However, how nuclear oscillations help pairing is unknown.
Mariola R. Chacón +2 more
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PLoS Genetics, 2012 The pairing of homologous chromosomes is a fundamental feature of the meiotic cell. In addition, a number of species exhibit homolog pairing in nonmeiotic, somatic cells as well, with evidence for its impact on both gene regulation and double-strand ...
Eric F Joyce +3 more
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Theory of phase segregation in DNA assemblies containing two different base pair sequence types [PDF]
, 2016 Spontaneous pairing of homologous DNA sequences – a challenging subject in molecular biophysics, often referred to as ‘homology recognition’ – ha s been observed in vitro for several DNA system s a . One of th e se experiments involved liquid crystalline
Kornyshev, AA, Lee, DJ, Wynveen, A
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PLoS Computational BiologyDuring meiosis, pairing of homologous chromosomes (homologs) ensures the formation of haploid gametes from diploid precursor cells, a prerequisite for sexual reproduction.
Ariana Chriss +2 more
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Which one is the real matchmaker for the pair?
Asian Journal of Andrology, 2014 A fundamental question for meiosis is how homologous chromosomes (homologs) find each other and pair together to ensure homologous recombination and segregation.
Chunsheng Han
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Chromosome painting reveals asynaptic full alignment of homologs and HIM-8-dependent remodeling of X chromosome territories during Caenorhabditis elegans meiosis. [PDF]
PLoS Genetics, 2011 During early meiotic prophase, a nucleus-wide reorganization leads to sorting of chromosomes into homologous pairs and to establishing associations between homologous chromosomes along their entire lengths.
Kentaro Nabeshima +2 more
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