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Meiotic chromosome dynamics and double strand break formation in reptiles
During meiotic prophase I, tightly regulated processes take place, from pairing and synapsis of homologous chromosomes to recombination, which are essential for the generation of genetically variable haploid gametes.
Laia Marín-Gual +11 more
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Hochschild homology and split pairs
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Bergh, Petter Andreas, Madsen, Dag
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Crossover recombination during meiosis is accompanied by a dramatic chromosome reorganization. In Saccharomyces cerevisiae, the onset of meiotic recombination by the Spo11 transesterase leads to stable pairwise associations between previously ...
Lina Yisehak, Amy J. MacQueen
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A surge of late-occurring meiotic double-strand breaks rescues synapsis abnormalities in spermatocytes of mice with hypomorphic expression of SPO11 [PDF]
Meiosis is the biological process that, after a cycle of DNA replication, halves the cellular chromosome complement, leading to the formation of haploid gametes.
Barchi, Marco +9 more
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Chromosome segregation in plant meiosis [PDF]
Faithful chromosome segregation in meiosis is essential for ploidy stability over sexual life cycles. In plants, defective chromosome segregation caused by gene mutations or other factors leads to the formation of unbalanced or unreduced gametes creating
De Storme, Nico +4 more
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Homologous Pairing Promoted by the Human Rad52 Protein [PDF]
The Rad52 protein, which is unique to eukaryotes, plays important roles in the Rad51-dependent and the Rad51-independent pathways of DNA recombination. In the present study, we have biochemically characterized the homologous pairing activity of the HsRad52 protein (Homo sapiens Rad52) and found that the presynaptic complex formation with ssDNA is ...
W, Kagawa +4 more
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Finding the Correct Partner: The Meiotic Courtship
Homologous chromosomes are usually separated at the entrance of meiosis; how they become paired is one of the outstanding mysteries of the meiotic process.
Tomás Naranjo
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The intrinsic ability of double-stranded DNA to carry out D-loop and R-loop formation
Double-stranded (ds)DNA, not dsRNA, has an ability to form a homologous complex with single-stranded (ss)DNA or ssRNA of homologous sequence. D-loops and homologous triplexes are homologous complexes formed with ssDNA by RecA/Rad51-family homologous ...
Takehiko Shibata +2 more
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Modeling cell biological features of meiotic chromosome pairing to study interlock resolution.
During meiosis, homologous chromosomes become associated side by side in a process known as homologous chromosome pairing. Pairing requires long range chromosome motion through a nucleus that is full of other chromosomes.
Erik J Navarro +2 more
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Chromosome assignment of two cloned DNA probes hybridizing predominantly to human sex chromosomes [PDF]
In situ hybridization experiments were carried out with two clones, YACG 35 and 2.8, which had been selected from two genomic libraries strongly enriched for the human Y chromosome.
A Chapelle de la +34 more
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