Results 21 to 30 of about 2,294,281 (319)

DNA-pairing and annealing processes in homologous recombination and homology-directed repair. [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2015
The formation of heteroduplex DNA is a central step in the exchange of DNA sequences via homologous recombination, and in the accurate repair of broken chromosomes via homology-directed repair pathways. In cells, heteroduplex DNA largely arises through the activities of recombination proteins that promote DNA-pairing and annealing reactions. Classes of
S. Morrical
semanticscholar   +3 more sources

Regulation of DNA pairing in homologous recombination. [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2014
Homologous recombination (HR) is a major mechanism for eliminating DNA double-strand breaks from chromosomes. In this process, the break termini are resected nucleolytically to form 3' ssDNA (single-strand DNA) overhangs. A recombinase (i.e., a protein that catalyzes homologous DNA pairing and strand exchange) assembles onto the ssDNA and promotes ...
J. Daley   +3 more
semanticscholar   +3 more sources

C-DNA may facilitate homologous DNA pairing.

open access: yesTrends in Genetics, 2023
Recombination-independent homologous pairing represents a prominent yet largely enigmatic feature of chromosome biology. As suggested by studies in the fungus Neurospora crassa, this process may be based on the direct pairing of homologous DNA molecules.
A. Mazur, Eugene Gladyshev
semanticscholar   +1 more source

The embedded homology of hypergraph pairs

open access: yesJournal of Knot Theory and Its Ramifications, 2022
In this paper, we generalize the embedded homology groups of hypergraphs initially given in [S. Bressan, J. Li, S. Ren and J. Wu, The embedded homology of hypergraphs and applications, Asian J. Math. 23(3) (2019) 479–500] and study the relative embedded homology groups of hypergraph pairs. We prove some long exact sequences as well as a Mayer–Vietoris
Ren, Shiquan, Wu, Jie, Zhang, Mengmeng
openaire   +2 more sources

Telomeres and Subtelomeres Dynamics in the Context of Early Chromosome Interactions During Meiosis and Their Implications in Plant Breeding

open access: yesFrontiers in Plant Science, 2021
Genomic architecture facilitates chromosome recognition, pairing, and recombination. Telomeres and subtelomeres play an important role at the beginning of meiosis in specific chromosome recognition and pairing, which are critical processes that allow ...
Miguel Aguilar, Pilar Prieto
doaj   +1 more source

Differing requirements for RAD51 and DMC1 in meiotic pairing of centromeres and chromosome arms in Arabidopsis thaliana. [PDF]

open access: yesPLoS Genetics, 2012
During meiosis homologous chromosomes pair, recombine, and synapse, thus ensuring accurate chromosome segregation and the halving of ploidy necessary for gametogenesis.
Olivier Da Ines   +4 more
doaj   +1 more source

Meiotic chromosome pairing is promoted by telomere-led chromosome movements independent of bouquet formation. [PDF]

open access: yesPLoS Genetics, 2012
Chromosome pairing in meiotic prophase is a prerequisite for the high fidelity of chromosome segregation that haploidizes the genome prior to gamete formation. In the budding yeast Saccharomyces cerevisiae, as in most multicellular eukaryotes, homologous
Chih-Ying Lee   +2 more
doaj   +1 more source

Homolog Pairing at the Push of a Button [PDF]

open access: yesDevelopmental Cell, 2019
Homologous chromosomes pair in somatic cells in Drosophila, but how this occurs is poorly understood. In this issue of Developmental Cell, Viets et al. (2019) show that proteins and chromatin structure mediate pairing and argue against a DNA sequence-based mechanism.
Bateman, Jack R., Kassis, Judith A.
openaire   +2 more sources

Determinants of Chromosome Architecture: Insulator Pairing in cis and in trans. [PDF]

open access: yesPLoS Genetics, 2016
The chromosomes of multicellular animals are organized into a series of topologically independent looped domains. This domain organization is critical for the proper utilization and propagation of the genetic information encoded by the chromosome.
Miki Fujioka   +3 more
doaj   +1 more source

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