Results 201 to 210 of about 651,783 (359)

The PP2A‐B56 Binding Site LxxIxE Contributes to Asp‐Mediated Spindle Pole Stability

open access: yesCytoskeleton, EarlyView.
ABSTRACT The organization of microtubules into a mitotic spindle is critical for animal cell proliferation and involves the cooperation of hundreds of proteins whose molecular roles and regulation are not fully understood. The protein product of the Drosophila gene abnormal spindle, Asp, is a microtubule‐associated protein required for correct mitotic ...
Margaux Quiniou   +6 more
wiley   +1 more source

Harnessing Viral Proteases for Cellular and Molecular Engineering

open access: yesChemistry–Methods, EarlyView.
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui   +2 more
wiley   +1 more source

USP4 Auto-Deubiquitylation Promotes Homologous Recombination. [PDF]

open access: yesMol Cell
Wijnhoven P   +6 more
europepmc   +1 more source

Inorganic Metal Nanoparticles in Reproductive Biology: Applications, Toxicities and Future Prospects

open access: yesChemPlusChem, EarlyView.
Metal nanoparticles (MNPs) have shown great promise in the livestock industry such as semen collection, nano‐purification, cryopreservation, sex sorting, bioimaging, drug and gene delivery. However, reproductive toxicity induced by MNP has adverse effects on various sexual functions including poor sperm parameters, testicular damage, ovary injury, and ...
Sangita Kundu   +3 more
wiley   +1 more source

Rebuilding ships while at sea—Character individuality, homology, and evolutionary innovation

open access: yesJournal of Morphology, Volume 284, Issue 1, January 2023., 2023
Building on a previous account of evolutionary innovation, I propose here that evolutionary novelties are those individualized characters that are not homologous to any characters in the ancestor. Integrating functional and structural perspectives, I argue that functional as well as structural considerations are important for character ...
Gerhard Schlosser
wiley   +1 more source

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