Results 201 to 210 of about 348,739 (321)

Homoterpene Biosynthesis in Fungi

Angewandte Chemie International Edition, EarlyView.
The first homoterpene biosynthetic pathway in the fungal kingdom is reported. A methyltransferase–terpene cyclase pair produces a unique heptamethyl bicyclo[3.3.1]nonane homoterpene via presodorifen, demonstrating that homoterpene biosynthesis via the addition of a C1 unit to terpene diphosphate precursors prior to scaffold formation extends beyond the
Lin Zhou, Tatjana Reuter, Kiara Schumann, Markus Mayer, Dominik Matthias Hanauska, Lena Barra   +5 more
wiley   +1 more source

Analytical validation of a homologous recombination deficiency signature (HRDsig) in pan-tumor tissue samples. [PDF]

PLoS One
Li W, Leibowitz JA, Wang S, Walker L, Xu C, Chen KT, Schrock AB, Hughes J, Patel N, Elvin JA, Ritterhouse LL, Sokol E, Frampton G, Dennis L, Yilmazel B, Decker B.   +15 more
europepmc   +1 more source

Homologous Recombination [PDF]

, 2005
openaire   +1 more source

Dietary Mannan‐Rich Fractions Attenuate Weaning Stress in Piglets via Modulating Gut Microbiota and TLR5/NF‐κB Signaling

Animal Research and One Health, EarlyView.
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu, Yiwei Sun, Kun Cai, Pingli He, Gang Lin, Zengkai Qi, Hu Liu, Junshu Yan, Ning Ma   +8 more
wiley   +1 more source

Homologous Recombination Deficiency Testing in Women With Ovarian Cancer: An Egyptian Multicentre Study. [PDF]

BJOG
Shohdy KS, Kassem L, Gabriel B, Barsoum E, Elnahas T, Azim HA.   +5 more
europepmc   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Regulators of homologous recombination deficiency identified by machine learning using somatic multi-omics data. [PDF]

Life Sci Alliance
Valieris R, Rosa L, Martins L, Defelicibus A, Carraro DM, Nunes DN, Dias-Neto E, Rosales R, da Silva IT.   +8 more
europepmc   +1 more source

Mechanism of the concerted action of recA protein and helix-destabilizing proteins in homologous recombination.

, 1984
K. Muniyappa, Sandra L. Shaner, S.S. Tsang, Charles M. Radding   +3 more
openalex   +2 more sources

Enhanced Production of Astaxanthin and Zeaxanthin by Paracoccus Sp. LL1 Through Random Mutagenesis

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Astaxanthin, a high‐value carotenoid with potent antioxidant and anti‐inflammatory activities, is increasingly in demand in various industries. This study reports the successful enhancement of astaxanthin and zeaxanthin production in Paracoccus sp. LL1 through random mutagenesis using ethyl methanesulfonate (EMS).
Anoth Maharjan, Beom Soo Kim
wiley   +1 more source

Inactivation of ku80 in the mushroom-forming fungus Schizophyllum commune increases the relative incidence of homologous recombination [PDF]

, 2010
Jan F. de Jong, Robin A. Ohm, Charissa de Bekker, Han A. B. Wösten, Luis G. Lugones   +4 more
openalex   +1 more source