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Homologous Recombination in Negative Sense RNA Viruses

open access: yesViruses, 2011
Recombination is an important process that influences biological evolution at many different levels. More and more homologous recombination events have been reported among negative sense RNA viruses recently.
Michael Worobey, Guan-Zhu Han
doaj   +1 more source

Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51

open access: yesNature Communications, 2022
Sister chromatid exchanges (SCEs) are considered to be products of homologous recombination repair. The authors show that SCEs can arise independently of homologous recombination due to processing of replication intermediates during mitosis.
Anne Margriet Heijink   +18 more
doaj   +1 more source

Homologous Recombination under the Single-Molecule Fluorescence Microscope [PDF]

open access: yes, 2019
Homologous recombination (HR) is a complex biological process and is central to meiosis and for repair of DNA double-strand breaks. Although the HR process has been the subject of intensive study for more than three decades, the complex protein–protein ...
Dhakal, Soma, Gibbs, Dalton R.
core   +2 more sources

No observed effect of homologous recombination on influenza C virus evolution

open access: yesVirology Journal, 2010
The occurrence of homologous recombination in influenza viruses has been under some debate recently. To determine the extent of homologous recombination in influenza C virus, recombination analyses of all available gene sequences of influenza C virus ...
Boni Maciej F, Han Guan-Zhu, Li Si-Shen
doaj   +1 more source

Phylogenetic evidence for homologous recombination within the family Birnaviridae [PDF]

open access: yes, 2008
Birnaviruses are bi-segmented double-stranded RNA (dsRNA) viruses infecting insects, avian species and a wide range of aquatic species. Although homologous recombination is a common phenomenon in positive-sense RNA viruses, recombination in dsRNA viruses
Hon, CC   +7 more
core   +1 more source

Recombination: Homologous recombination branches out [PDF]

open access: yesCurrent Biology, 2001
Homologous recombination can be divided into three key steps: strand exchange, branch migration and resolution. The identification of a protein complex that catalyses branch migration and Holliday junction resolution argues that the mechanism of homologous recombination is conserved from bacteria to man.
openaire   +2 more sources

Rad54: the Swiss Army knife of homologous recombination? [PDF]

open access: yes, 2006
Homologous recombination (HR) is a ubiquitous cellular pathway that mediates transfer of genetic information between homologous or near homologous (homeologous) DNA sequences. During meiosis it ensures proper chromosome segregation in the first division.
Heyer, Wolf-Dietrich   +3 more
core   +2 more sources

SUMOylation of Rad52-Rad59 synergistically change the outcome of mitotic recombination [PDF]

open access: yes, 2016
Homologous recombination (HR) is essential for maintenance of genome stability through double-strand break (DSB) repair, but at the same time HR can lead to loss of heterozygosity and uncontrolled recombination can be genotoxic.
Lisby, Michael, Silva, Sonia
core   +1 more source

Regulation Mechanisms of Meiotic Recombination Revealed from the Analysis of a Fission Yeast Recombination Hotspot ade6-M26

open access: yesBiomolecules, 2022
Meiotic recombination is a pivotal event that ensures faithful chromosome segregation and creates genetic diversity in gametes. Meiotic recombination is initiated by programmed double-strand breaks (DSBs), which are catalyzed by the conserved Spo11 ...
Kouji Hirota
doaj   +1 more source

Homolog pairing during meiosis : dyneins on the move [PDF]

open access: yes, 2010
Meiosis is a specialized form of cell division that generates haploid gametes from diploid cells. This is achieved by having 1 round of DNA replication followed by 2 rounds of nuclear division.
Arumugam, Prakash
core   +1 more source

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