Results 21 to 30 of about 773,827 (377)

Homologous Recombination: Down to the Wire [PDF]

Current Biology, 2004
Exchange of strands between homologous DNA molecules is catalyzed by evolutionarily conserved recombinases. These proteins can occur in different quaternary arrangements: rings or helical filaments. Recent results reveal that recombinase function follows from the filamentous form.
Roland Kanaar, Claire Wyman
openaire   +3 more sources

m5C modification of mRNA serves a DNA damage code to promote homologous recombination

Nature Communications, 2020
Recruitment of DNA repair proteins to DNA damage sites is a critical step for DNA repair. Post-translational modifications of proteins at DNA damage sites serve as DNA damage codes to recruit specific DNA repair factors.
Hao Chen, Haibo Yang, Xiao-Long Zhu, Tribhuwan Yadav, Ouyang Jian, S. Truesdell, Jun Tan, Yumin Wang, Meihan Duan, Leizhen Wei, L. Zou, A. Levine, S. Vasudevan, Li Lan   +13 more
semanticscholar   +1 more source

Double-strand break repair and homologous recombination in Schizosaccharomyces pombe [PDF]

, 2006
In recent years our understanding of double strand break repair and homologous recombination in Schizosaccharomyces pombe has increased significantly, and the identification of novel pathways and genes with homologues in higher eukaryotes has increased ...
Ahmad, Ahmad, Ahn, Ahnesorg, Akamatsu, Assenmacher, Baumann, Boddy, Boddy, Bonatto, Bransteitter, Buck, Callebaut, Caspari, Catlett, Cervantes, Chahwan, Cheok, Connelly, Cooper, Doe, Doe, Doe, Doe, Dudasova, Farah, Farah, Ferreira, Ferreira, Fukushima, Gaillard, Goedecke, Goodwin, Grishchuk, Haber, Hartsuiker, Hefferin, Jang, Jung, Khasanov, Khasanov, Kibe, Kim, Kim, Krogh, Lambert, Laursen, Macris, Maftahi, Maftahi, Manolis, Marchetti, Martin, McGlynn, Moore, Morishita, Muris, Muris, Muris, Murray, Nakada, Nakamura, Oakley, Ono, Osman, Osman, Osman, Ostermann, Paques, Parker, Prudden, Sauvageau, Schmidt, Segurado, Shinohara, Smith, Steiner, Stewart, Sung, Suto, Szankasi, Szostak, Tarsounas, Tavassoli, Thacker, Tomita, Tomita, Tsutsui, Tsutsui, Ueno, van den Bosch, van den Bosch, Virgin, Virgin, Wang, Weterings, Whitby, Whitby, Wilson, Win, Win, You, Young   +102 more
core   +2 more sources

Homologous recombination and its regulation [PDF]

Nucleic Acids Research, 2012
Homologous recombination (HR) is critical both for repairing DNA lesions in mitosis and for chromosomal pairing and exchange during meiosis. However, some forms of HR can also lead to undesirable DNA rearrangements. Multiple regulatory mechanisms have evolved to ensure that HR takes place at the right time, place and manner. Several of these impinge on
Mário Špírek, Lumir Krejci, Xiaolan Zhao, Veronika Altmannova   +3 more
openaire   +3 more sources

PALB2 self-interaction controls homologous recombination. [PDF]

, 2012
PALB2 is essential for BRCA2 anchorage to nuclear structures and for homologous recombinational repair of DNA double-strand breaks. Here, we report that the N-terminal coiled-coil motif of PALB2 regulates its self-association and homologous recombination.
Buisson, Rémi, Masson, Jean-Yves
core   +1 more source

Intermolecular Homologous Recombination in Plants [PDF]

Molecular and Cellular Biology, 1990
To study DNA topological requirements for homologous recombination in plants, we have constructed pairs of plasmids that contain nonoverlapping deletions in the neomycin phosphotransferase gene [APH(3')II], which, when intact, confers kanamycin resistance to plant cells.
M Baur, Jerzy Dr. Paszkowski, I Potrykus
openaire   +3 more sources

Homologous Recombination as a Replication Fork Escort: Fork-Protection and Recovery

Biomolecules, 2012
Homologous recombination is a universal mechanism that allows DNA repair and ensures the efficiency of DNA replication. The substrate initiating the process of homologous recombination is a single-stranded DNA that promotes a strand exchange reaction ...
Audrey Costes, Sarah A. E. Lambert
doaj   +1 more source

High fidelity of RecA-catalyzed recombination: a watchdog of genetic diversity [PDF]

, 2006
Homologous recombination plays a key role in generating genetic diversity, while maintaining protein functionality. The mechanisms by which RecA enables a single-stranded segment of DNA to recognize a homologous tract within a whole genome are poorly ...
Sagi, Dror, Stavans, Joel, Tlusty, Tsvi
core   +6 more sources

Dependence of frequency of homologous recombination on the homology length. [PDF]

Genetics, 1995
Abstract The frequency of homologous recombination is believed to be a linear function of the length (N bp) of homology between DNAs. Here, the N intercept is believed to be determined by a threshold length below which some physical constraint is effective.
Ichizo Kobayashi, Youhei Fujitani, Kimiko Yamamoto   +2 more
openaire   +4 more sources

Homologous Recombination in Negative Sense RNA Viruses

Viruses, 2011
Recombination is an important process that influences biological evolution at many different levels. More and more homologous recombination events have been reported among negative sense RNA viruses recently.
Michael Worobey, Guan-Zhu Han
doaj   +1 more source