Results 31 to 40 of about 510,614 (286)

Smc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisions [PDF]

, 2013
During meiosis, Structural Maintenance of Chromosome (SMC) complexes underpin two fundamental features of meiosis: homologous recombination and chromosome segregation.
Philip W. Jordan (265255), Copsey A., Prakash Arumugam, Sonya Newcombe (502072), Jordan, Philip W., Gray S., Alice Copsey (4460686), Alex D Herbert, Eva Hoffmann (159398), Li, Zhaobo, Shangming Tang, Zhaobo Li, Stephen Gray, Newnham, Louise, Herbert A.D., Chan, Andrew Chi-ho, Hannah G. Blitzblau (159462), Blitzblau, Hannah G., Gray, Stephen, Alex Herbert (725932), Hannah G Blitzblau, Hannah Blitzblau (5185454), Newcombe S., Tang, Shangming, Stephen Gray (3278418), Newnham L., Li Z., Hunter, Neil, Andrew Chi-ho Chan (3278421), Hochwagen, Andreas, Arumugam, Prakash, Shangming Tang (502071), Hochwagen A., Alice Copsey, Alice Copsey (502070), Copsey, Alice, Herbert, Alex D., Hoffmann E., Blitzblau H.G., Andreas Hochwagen (159466), Arumugam P., Louise Newnham, Neil Hunter, Philip W Jordan (16188074), Jordan P.W., Alex D. Herbert (502074), Philip W Jordan, Andrew Chi-Ho Chan, Louise Newnham (430862), Sonya Newcombe, Chan, Andrew Chi ho, Tang S., Prakash Arumugam (303310), Eva Hoffmann, Newcombe, Sonya, Andreas Hochwagen, Hunter N., Chan A.C.-h., Neil Hunter (155061), Steve Gray (5950955), Zhaobo Li (502073), Hoffmann, Eva   +61 more
core   +1 more source

No observed effect of homologous recombination on influenza C virus evolution

Virology Journal, 2010
The occurrence of homologous recombination in influenza viruses has been under some debate recently. To determine the extent of homologous recombination in influenza C virus, recombination analyses of all available gene sequences of influenza C virus ...
Boni Maciej F, Han Guan-Zhu, Li Si-Shen
doaj   +1 more source

Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51

Nature Communications, 2022
Sister chromatid exchanges (SCEs) are considered to be products of homologous recombination repair. The authors show that SCEs can arise independently of homologous recombination due to processing of replication intermediates during mitosis.
Anne Margriet Heijink, Colin Stok, David Porubsky, Eleni Maria Manolika, Jurrian K. de Kanter, Yannick P. Kok, Marieke Everts, H. Rudolf de Boer, Anastasia Audrey, Femke J. Bakker, Elles Wierenga, Marcel Tijsterman, Victor Guryev, Diana C. J. Spierings, Puck Knipscheer, Ruben van Boxtel, Arnab Ray Chaudhuri, Peter M. Lansdorp, Marcel A. T. M. van Vugt   +18 more
doaj   +1 more source

ruvA Mutants that resolve Holliday junctions but do not reverse replication forks [PDF]

, 2008
RuvAB and RuvABC complexes catalyze branch migration and resolution of Holliday junctions (HJs) respectively. In addition to their action in the last steps of homologous recombination, they process HJs made by replication fork reversal, a reaction which ...
Bradley Alison Sylvia, Tsaneva, I, Tsaneva Irina, Bénédicte Michel, Baharoglu Zeynep, Irina Tsaneva, Zeynep Baharoglu, Marie Le Masson, Michel, B, Bradley, AS, Baharoglu, Z, Le Masson Marie, Michel Bénédicte, Alison Sylvia Bradley, Le Masson, M   +14 more
core   +2 more sources

Recombination in enteroviruses is a biphasic replicative process involving the generation of greater-than genome length 'imprecise' intermediates [PDF]

, 2014
Recombination in enteroviruses provides an evolutionary mechanism for acquiring extensive regions of novel sequence, is suggested to have a role in genotype diversity and is known to have been key to the emergence of novel neuropathogenic variants of ...
David J Evans, Woodman, Andrew, Andrew Woodman, Kym Lowry (222718), Jonathan Cook (3435386), Andrew Woodman (577477), Cook, Jonathan, Cook, Jonathan P., David J. Evans (208308), Lowry, Kym, David J. Evans, Evans, David J., Kym Lowry, Jonathan Cook   +13 more
core   +1 more source

ASYNAPSIS 1 ensures crossover fidelity in polyploid wheat by promoting homologous recombination and suppressing non-homologous recombination [PDF]

, 2023
During meiosis, the chromosome axes and synaptonemal complex mediate chromosome pairing and homologous recombination to maintain genomic stability and accurate chromosome segregation.
Sourdille, Pierre, Pierre Sourdille, Chiara Di Dio, Heïdi Serra, Serra, Heïdi, James D. Higgins, Di Dio, Chiara, Higgins, James, D   +7 more
core   +1 more source

Loss of CYLD on Chromosome 16q Impairs Homologous Recombination and Genomic Stability Through TIRR Degradation. [PDF]

Adv Sci (Weinh)
Chromosome 16q loss drives genomic instability through disruption of the CYLD–TIRR–53BP1 axis. CYLD preserves homologous recombination by stabilizing TIRR and limiting 53BP1 accumulation at DNA double‐strand breaks. CYLD deficiency redirects repair toward error‐prone non‐homologous end joining, promotes mutational burden and homologous recombination ...
Lu M, Kang J, Ye Q, Wang Z, Li L, Lei Y, Ye L, Liu T, Wang B, Liu T, Xu S, Wang K, Zhang Y, Ma J, Li L.   +14 more
europepmc   +2 more sources

The XPF-ERCC1 endonuclease and homologous recombination contribute to the repair of minor groove DNA interstrand crosslinks inmammalian cells produced by the pyrrolo[2,1-c][1,4]benzodiazepine dimer SJG-136 [PDF]

, 2005
SJG-136, a pyrrolo[2,1-c][1,4]benzodiazepine (PBD) dimer, is a highly efficient interstrand crosslinking agent that reacts with guanine bases in a 5'-GATC-3' sequence in the DNA minor groove.
Hartley, J.A., Ghadessy, Farid J, De Silva, I.U., Thurston, DE, Thurston, D.E., Clingen, PH, Ghadessy, FJ, Tilby, M.J., De Silva, IU, De Silva, Inusha U, Tilby, Michael J, Hartley, JA, McHugh, Peter J, Ghadessy, F.J., Clingen, Peter H, McHugh, P.J., Tilby, MJ, Hartley, John A, Thurston, David E, Clingen, P.H., McHugh, PJ   +20 more
core   +1 more source

Regulation Mechanisms of Meiotic Recombination Revealed from the Analysis of a Fission Yeast Recombination Hotspot ade6-M26

Biomolecules, 2022
Meiotic recombination is a pivotal event that ensures faithful chromosome segregation and creates genetic diversity in gametes. Meiotic recombination is initiated by programmed double-strand breaks (DSBs), which are catalyzed by the conserved Spo11 ...
Kouji Hirota
doaj   +1 more source

High Rates of Homologous Recombination in the Mite Endosymbiont and Opportunistic Human Pathogen Orientia tsutsugamushi [PDF]

, 2010
The study was funded by the Wellcome Trust. PS was supported by grants from the Wellcome Trust (073135) and British Infection Society.Orientia tsutsugamushi is an intracellular alpha-proteobacterium which resides in trombiculid mites, and is the ...
Feil, EJ, Sonthayanon Piengchan, Wuthiekanun Vanaporn, Stuart D Blacksell, Sharon J Peacock, Blacksell, SD, Bentley Stephen D., Sharon J. Peacock, Bentley, SD, Day, Nicholas P. J., Feil Edward J., Day Nicholas P. J., Stephen D. Bentley, Sonthayanon, P, Chierakul, Wirongrong, Stephen D Bentley, Blacksell, Stuart D., Chierakul Wirongrong, Piengchan Sonthayanon, Stuart D. Blacksell, Day, NP, Bentley, Stephen D., Nicholas P J Day, Holden, MT, Wirongrong Chierakul, Mathew T G Holden, Peacock, Sharon J., Feil, Edward J., Wuthiekanun, Vanaporn, Peacock, SJ, Edward J Feil, Wuthiekanun, V, Nicholas P. J. Day, Sonthayanon, Piengchan, Blacksell, Stuart, Vanaporn Wuthiekanun, Edward J. Feil, Chierakul, W, Peacock Sharon J., Day, Nicholas, Holden, Mathew T. G., Holden, Matthew, Blacksell Stuart D., Holden Mathew T. G., Mathew T. G. Holden   +44 more
core   +2 more sources