Results 21 to 30 of about 341,184 (291)

No observed effect of homologous recombination on influenza C virus evolution

Virology Journal, 2010
The occurrence of homologous recombination in influenza viruses has been under some debate recently. To determine the extent of homologous recombination in influenza C virus, recombination analyses of all available gene sequences of influenza C virus ...
Boni Maciej F, Han Guan-Zhu, Li Si-Shen
doaj   +1 more source

Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51

Nature Communications, 2022
Sister chromatid exchanges (SCEs) are considered to be products of homologous recombination repair. The authors show that SCEs can arise independently of homologous recombination due to processing of replication intermediates during mitosis.
Anne Margriet Heijink, Colin Stok, David Porubsky, Eleni Maria Manolika, Jurrian K. de Kanter, Yannick P. Kok, Marieke Everts, H. Rudolf de Boer, Anastasia Audrey, Femke J. Bakker, Elles Wierenga, Marcel Tijsterman, Victor Guryev, Diana C. J. Spierings, Puck Knipscheer, Ruben van Boxtel, Arnab Ray Chaudhuri, Peter M. Lansdorp, Marcel A. T. M. van Vugt   +18 more
doaj   +1 more source

Homologous Recombination: To Fork and Beyond [PDF]

, 2018
Accurate completion of genome duplication is threatened by multiple factors that hamper the advance and stability of the replication forks. Cells need to tolerate many of these blocking lesions to timely complete DNA replication, postponing their repair ...
Prado Velasco, José Félix
core   +1 more source

DNA resection in eukaryotes: deciding how to fix the break [PDF]

, 2010
DNA double-strand breaks are repaired by different mechanisms, including homologous recombination and nonhomologous end-joining. DNA-end resection, the first step in recombination, is a key step that contributes to the choice of DSB repair.
A Aguilera, A Jazayeri, A Jazayeri, A Penkner, AA Sartori, AH McKee, AV Nimonkar, B Gu, BB Hopkins, BM Lengsfeld, BO Krogh, C Uanschou, C Zierhut, CF Cheok, CJ Lord, D Mantiero, D Nakada, DA Bressan, DO Warmerdam, E Baroni, EP Mimitou, F Lazzaro, G Chinnadurai, G Ira, G Wu, I Morin, J Buis, J Falck, JC Harrison, JH Barlow, JH Kim, JP Duxin, K Lee, K Shimada, KM Trujillo, L Chen, L Chen, L Maringele, L Zheng, M Clerici, M Clerici, M Grenon, M Lisby, M McVey, MF Lavin, MH Yun, MJ Neale, MR Lieber, O Limbo, P Huertas, P Huertas, Pablo Huertas, PL Chen, PT Tran, R Linding, R Waltes, RR Khakhar, RS Williams, S Gravel, S Liao, S Moreau, S Prinz, SH Bae, SK Amundsen, T Usui, TH Stracker, TT Paull, WS Dynan, X Yu, X Yu, Y Akamatsu, Y Aylon, Y Zhang, Z Horejsí, Z Zhu   +74 more
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Homolog pairing during meiosis : dyneins on the move [PDF]

, 2010
Meiosis is a specialized form of cell division that generates haploid gametes from diploid cells. This is achieved by having 1 round of DNA replication followed by 2 rounds of nuclear division.
Arumugam, Prakash
core   +1 more source

Phylogenetic evidence for homologous recombination within the family Birnaviridae [PDF]

, 2008
Birnaviruses are bi-segmented double-stranded RNA (dsRNA) viruses infecting insects, avian species and a wide range of aquatic species. Although homologous recombination is a common phenomenon in positive-sense RNA viruses, recombination in dsRNA viruses
Hon, CC, Jiang, J, Lam, TTY, Leung, FCC, Shi, M, Wong, RTY, Yip, CW, Zeng, F   +7 more
core   +1 more source

Regulation Mechanisms of Meiotic Recombination Revealed from the Analysis of a Fission Yeast Recombination Hotspot ade6-M26

Biomolecules, 2022
Meiotic recombination is a pivotal event that ensures faithful chromosome segregation and creates genetic diversity in gametes. Meiotic recombination is initiated by programmed double-strand breaks (DSBs), which are catalyzed by the conserved Spo11 ...
Kouji Hirota
doaj   +1 more source

Mouse WRN Helicase Domain Is Not Required for Spontaneous Homologous Recombination-Mediated DNA Deletion

Journal of Nucleic Acids, 2010
Werner syndrome is a rare disorder that manifests as premature aging and age-related diseases. WRN is the gene mutated in WS, and is one of five human RecQ helicase family members.
Adam D. Brown, Alison B. Claybon, Alexander J. R. Bishop   +2 more
doaj   +1 more source

High-resolution mapping of heteroduplex DNA formed during UV-induced and spontaneous mitotic recombination events in yeast. [PDF]

, 2017
In yeast, DNA breaks are usually repaired by homologous recombination (HR). An early step for HR pathways is formation of a heteroduplex, in which a single-strand from the broken DNA molecule pairs with a strand derived from an intact DNA molecule.
Dominska, Margaret, Petes, Thomas D, Yim, Eunice, Yin, Yi   +3 more
core   +3 more sources

The extent of error-prone replication-restart by homologous recombination is controlled by Exo1 and checkpoint proteins [PDF]

, 2014
Genetic instability, a hallmark of cancer, can occur when the replication machinery encounters a barrier. The intra-S phase checkpoint maintains stalled replication forks in a replication-competent configuration by phosphorylating replisome components ...
Ahn, Alabert, Bailis, Barlow, Bastia, Bester, Biswas, Boddy, Bolderson, Brown, Bähler, Carr, Carr, Casper, Cha, Chen, Cobb, Cobb, Codlin, Cotta-Ramusino, Dalgaard, De Piccoli, Durkin, El-Shemerly, Errico, Eydmann, Froget, Haghnazari, Halazonetis, Hartsuiker, Heichinger, Hu, Iraqui, Jia, Kai, Kaochar, Katou, Kolodner, Koundrioukoff, Krejci, Lambert, Lambert, Lambert, Lambert, Lambert, Lambert, Lee, Lindsay, Lisby, Lopes, Lucca, Maundrell, Meister, Mimitou, Miyabe, Miyabe, Mizuno, Mizuno, Moreau, Moreau, Moreno, Morin, Myung, Myung, Pandita, Raynard, Sabatinos, Segurado, Segurado, Smolka, Sogo, Stracker, Sun, Symington, Sørensen, Tercero, Tsubouchi, Watson, Zhu, Zou, Zubko   +80 more
core   +2 more sources