Results 61 to 70 of about 766,679 (374)
Replication dynamics of recombination-dependent replication forks
Nature Communications, 2021 Replication forks that are stalled at obstacles on the DNA template can be restarted by homologous recombination. Here, the authors show replication dynamics during homologous recombination-dependent replication fork restart by combining polymerase usage
Karel Naiman +5 more
doaj +1 more source
Intrachromosomal recombination mediated by the polyomavirus large T antigen [PDF]
, 1995 We used a spleen necrosis virus-based retroviral vector to introduce the polyomavirus replication origin into rat cells and developed a system to analyze homologous recombination events that do not reconstitute a selectable marker.
Alt +35 more
core +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Homologous recombination is unlikely to play a major role in influenza B virus evolution
Virology Journal, 2008 Influenza B viruses cause a significant amount of morbidity and mortality. The occurrence of homologous recombination in influenza viruses is controversial.
Liu Xi-Ping, Han Guan-Zhu, Li Si-Shen
doaj +1 more source
Keeping homologous recombination in check [PDF]
Cell Research, 2016 Pathway choice is a critical event in the repair of DNA double-strand breaks. In a recent paper published in Nature, Orthwein et al. define a mechanism by which homologous recombination is controlled in G1 cells to favor non-homologous end joining.
Stephen C. West, Kasper Fugger
openaire +2 more sources
SUMOylation of Rad52-Rad59 synergistically change the outcome of mitotic recombination [PDF]
, 2016 Homologous recombination (HR) is essential for maintenance of genome stability through double-strand break (DSB) repair, but at the same time HR can lead to loss of heterozygosity and uncontrolled recombination can be genotoxic.
Lisby, Michael, Silva, Sonia
core +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
MicroorganismsThe precise editing of genes mediated by CRISPR-Cas9 necessitates the application of donor DNA with appropriate lengths of homologous arms and fragment sizes.
Ran Chai +7 more
doaj +1 more source
PCR artifact in testing for homologous recombination in genomic editing in zebrafish. [PDF]
PLoS ONE, 2017 We report a PCR-induced artifact in testing for homologous recombination in zebrafish. We attempted to replace the lnx2a gene with a donor cassette, mediated by a TALEN induced double stranded cut.
Minho Won, Igor B Dawid
doaj +1 more source
Functional Analysis of the Human Genome, 2020 The process of exchange of genetic material between autonomous replicons, which depends on regions of extensive sequence homology between the participating DNA strands.
Ahmed Mansouri
semanticscholar +1 more source