Results 241 to 250 of about 137,826 (378)

Cosmic signature SBS39 is associated with homologous recombination deficiency

medRxiv
Y. Ding, S. Tao, A. Mao, E. Ziv, S. Neuhausen   +4 more
semanticscholar   +1 more source

Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function

Cytoskeleton, EarlyView.
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves, Katelyn Amstutz, Lily A. Schumacher, Iris Meier   +3 more
wiley   +1 more source

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

Cytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

Homologous Recombination Deficiency Testing in Women With Ovarian Cancer: An Egyptian Multicentre Study. [PDF]

BJOG
Shohdy KS, Kassem L, Gabriel B, Barsoum E, Elnahas T, Azim HA.   +5 more
europepmc   +1 more source

Data from Detection of Molecular Signatures of Homologous Recombination Deficiency in Bladder Cancer

, 2023
Judit Börcsök, Miklós Dióssy, Zsófia Sztupinszki, Aurél Prósz, Viktória Tisza, Sándor Spisák, Orsolya Rusz, Dag Rune Stormoen, Helle Pappot, István Csabai, Søren Brunak, Kent W. Mouw, Zoltán Szállási   +12 more
openalex   +1 more source

The Influence of Drosophila Spire and Myosin V During Mid‐Oogenesis Is Independent of Their Direct Interaction

Cytoskeleton, EarlyView.
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong, Hannah M. Bailey, Emma Carley, Michelle Panzica, Merin Rixen, Neil Billington, Rong Liu, Margot E. Quinlan   +7 more
wiley   +1 more source

The Role of Homologous Recombination Deficiency (HRD) in Renal Cell Carcinoma (RCC): Biology, Biomarkers, and Therapeutic Opportunities. [PDF]

Curr Oncol
Bongiovanni A, Conte P, Conteduca V, Landriscina M, Di Lorenzo G, Cognetti F.   +5 more
europepmc   +1 more source

Supplementary Table from Comparative Assessment of Diagnostic Homologous Recombination Deficiency–Associated Mutational Signatures in Ovarian Cancer

, 2023
Zsófia Sztupinszki, Miklós Dióssy, Judit Börcsök, Aurél Prósz, Nanna Cornelius, Maj K. Kjeldsen, Mansoor Raza Mirza, Zoltán Szállási   +7 more
openalex   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

Analytical validation of a homologous recombination deficiency signature (HRDsig) in pan-tumor tissue samples. [PDF]

PLoS One
Li W, Leibowitz JA, Wang S, Walker L, Xu C, Chen KT, Schrock AB, Hughes J, Patel N, Elvin JA, Ritterhouse LL, Sokol E, Frampton G, Dennis L, Yilmazel B, Decker B.   +15 more
europepmc   +1 more source