Homovanillic acid and 5-hydroxyindole acetic acid as biomarkers for dementia with Lewy bodies and coincident Alzheimer's disease: An autopsy-confirmed study. [PDF]
Dementia with Lewy bodies (DLB) and Alzheimer’s disease (AD) are the two most common causes of dementia. Both pathologies often coexist, and AD patients with concomitant neocortical LB pathology (referred to as the Lewy body variant of AD) generally show
Morimoto S +11 more
europepmc +4 more sources
Voltammetric Detection of Vanillylmandelic Acid and Homovanillic Acid Using Urea-Derivative-Modified Graphite Electrode [PDF]
Vanillylmandelic acid (VMA) and homovanillic acid (HVA) are diagnostic markers of neuroblastoma. The purpose of this study was to understand the reason for the discrimination of structural analogues (VMA and HVA) onto a graphite electrode coated with an ...
Tatiana V. Shishkanova +2 more
doaj +4 more sources
Updated Parkinson's disease motor subtypes classification and correlation to cerebrospinal homovanillic acid and 5-hydroxyindoleacetic acid levels [PDF]
Introduction: Motor classifications of Parkinson's Disease (PD) have been widely used. This paper aims to update a subtype classification using the MDS-UPDRS-III and determine if cerebrospinal neurotransmitter profiles (HVA and 5-HIAA) differ between ...
Christopher Adams +6 more
doaj +3 more sources
Application of an LC–MS/MS Method for the Simultaneous Quantification of Homovanillic Acid and Vanillylmandelic Acid for the Diagnosis and Follow-Up of Neuroblastoma in 357 Patients [PDF]
Homovanillic acid (HVA) and vanillylmandelic acid (VMA) are end-stage metabolites of catecholamine and are clinical biomarkers for the diagnosis of neuroblastoma.
Narae Hwang +6 more
doaj +4 more sources
Role of homovanillic acid esters in the regulation of skin inflammatory pathways and their effect on tight junction protein expression [PDF]
IntroductionIn the context of epidermal inflammation, the inflammatory response not only involves the release of inflammatory cytokines like interleukin 8 (IL-8), but also modulation of tight junction protein expression levels.
Maria Fernanda Cervantes Recalde +8 more
doaj +2 more sources
CSF xanthine, homovanillic acid, and their ratio as biomarkers of Parkinson's disease. [PDF]
LeWitt P +4 more
europepmc +3 more sources
A modified fluorimetric method for determination of hydrogen peroxide using homovanillic acid oxidation principle. [PDF]
Hydrogen peroxide (H2O2) level in biological samples is used as an important index in various studies. Quantification of H2O2 level in tissue fractions in presence of H2O2 metabolizing enzymes may always provide an incorrect result.
Paital B.
europepmc +2 more sources
A Modified Fenton’s System Fe2+–EGTA–H2O2 Reveals That Redox Activities of Simple Polyphenols Are Suppressed in Binary Mixtures [PDF]
Various polyphenols are absorbed into the bloodstream following the consumption of polyphenol-rich foods. These compounds may exhibit divergent redox properties, particularly in relation to their antioxidant or pro-oxidant activities.
Michał Nowak +5 more
doaj +2 more sources
Electrochemical Study and Determination of Homovanillic Acid, the Final Metabolite of Dopamine, Using an Unmodified Disposable Electrode [PDF]
This paper summarizes the main findings of a study which aimed to examine the electrochemical oxidation of homovanillic acid (HVA), the final metabolite of dopamine.
Mihaela Buleandră +5 more
doaj +2 more sources
Alterations in Monoamine Metabolites in Alzheimer's Disease: A Comprehensive Meta‐Analysis of Cerebrospinal Fluid Levels [PDF]
Abstract Background Alzheimer's disease (AD) is a neurodegenerative disorder marked by cognitive decline and neuropsychiatric symptoms. The monoaminergic system, crucial for mood, cognition, and behavior regulation, is implicated in AD pathology. Alterations in monoamine metabolites like 3,4‐dihydroxyphenylacetic acid (DOPAC), 5‐hydroxyindoleacetic ...
Muneer M +10 more
europepmc +4 more sources

