Results 81 to 90 of about 5,129,032 (295)

Biochemical analysis in congenital neuroblastoma

Advances in Laboratory Medicine, 2022
The incidence of congenital neuroblastoma has increased in the recent years. The purpose of this study was to describe the clinical and biochemical characteristics of cases of congenital neuroblastoma diagnosed in our center.
Montero Domínguez Cristina, Ortiz Temprado Alicia, Martínez Figueras Laura, Guillamón Seoane Alba, Fernández Ruano Miguel   +4 more
doaj   +1 more source

Challenges in the management of Phenylketonuria in Malta [PDF]

, 2016
Phenylketonuria (PKU) is a rare metabolic disorder comprising a number of different enzyme deficiencies. In Malta, dihydropteridine reductase (DHPR) deficiency appears to be more common than phenylalanine hydroxylase deficiency (classical PKU), and is ...
Attard Montalto, Simon, Attard, Stephen
core  

Biological Relevance of Extra Virgin Olive Oil Polyphenols Metabolites

Antioxidants, 2018
Extra virgin olive oil (EVOO) polyphenols beneficial effects have widely been debated throughout the last three decades, with greater attention to hydroxytyrosol and tyrosol, which are by far the most studied.
Gabriele Serreli, Monica Deiana
doaj   +1 more source

Elevated cerebrospinal fluid 5-hydroxyindoleacetic acid in macaques following early life stress and inverse association with hippocampal volume: preliminary implications for serotonin-related function in mood and anxiety disorders [PDF]

, 2014
Background: Early life stress (ELS) is cited as a risk for mood and anxiety disorders, potentially through altered serotonin neurotransmission. We examined the effects of ELS, utilizing the variable foraging demand (VFD) macaque model, on adolescent ...
Coplan, Jeremy D., Dwork, Andrew J., Fulton, Sasha L., Gorman, Jack M., Hof, Patrick R., Huang, Yung-yu, Jackowski, Andrea Parolin, Kaffman, Arie, Kaufman, Joan, Mann, J. John, Mathew, Sanjay J., Panthangi, Venkatesh, Perera, Tarique D., Reiner, Wade, Tang, Cheuk Y.   +14 more
core   +3 more sources

Comparison of Chromatographic Methods for Determination of the Major Metabolites of Catecholamines and Serotonin [PDF]

International Journal of Biomedicine, 2015
In the present review, we set out a new high-tech method for determining the major metabolites of catecholamines and serotonin in urine. We then discuss the effects of these substances and the value of their main metabolites in normal and various ...
Ilgar S. Mamedov, Irina V. Zolkina, Pavel B. Glagovsky, Vladimir S. Sukhorukov   +3 more
doaj  

Identification of (poly)phenol treatments that modulate the release of pro-inflammatory cytokines by human lymphocytes [PDF]

, 2016
Diets rich in fruits and vegetables (FV), which contain (poly)phenols, protect against age-related inflammation and chronic diseases. T-lymphocytes contribute to systemic cytokine production and are modulated by FV intake.
Crozier, Alan, Ford, Christopher T, Jackson, Malcolm J, Lotito, Silvina B, McArdle, Anne, McArdle, Francis, Richardson, Sian   +6 more
core   +1 more source

Derivatization of Small Molecules using Deuterated Analog of Reactive Matrix to Facilitate Identification in Mass Spectrometry Imaging

Chemistry–Methods, Volume 5, Issue 12, November 2025.
The deuterated FMP‐10 analog, FMP‐10‐d3, enhances identification through isotopic labeling, providing structural insights via unique mass shifts. The approach improves the analysis of neurotransmitters and metabolites, facilitating neurochemical mapping and spatial metabolomics, with applications in neurodegenerative disease research. Mass spectrometry
Theodosia Vallianatou, Lorenzo Jacopo Ilic Balestri, Anna Nilsson, Xiaoqun Zhang, Per Svenningsson, Luke R. Odell, Per E. Andrén, Reza Shariatgorji   +7 more
wiley   +1 more source

Opportunities and Challenges of the Application of Nuclear Magnetic Resonance‐Based Cerebrospinal Fluid Metabolomics for Clinical Research

Chemistry–Methods, Volume 5, Issue 12, November 2025.
Cerebrospinal fluid (CSF) is an important diagnostic matrix in neurology. This review illustrates the potentials and pitfalls of current CSF analysis by nuclear magnetic resonance. Created with BioRender.com in BioRender. Berezhnoy, G. (2025) https://BioRender.com/x80l903. Web of Science is owned by Clarivate.
Georgy Berezhnoy, Jannik Sprengel, Claire Cannet, Nils Pompe, Christoph Trautwein   +4 more
wiley   +1 more source

Biosensors for Brain Trauma and Dual Laser Doppler Flowmetry: Enoxaparin Simultaneously Reduces Stroke-Induced Dopamine and Blood Flow while Enhancing Serotonin and Blood Flow in Motor Neurons of Brain, In Vivo

Sensors, 2010
Neuromolecular Imaging (NMI) based on adsorptive electrochemistry, combined with Dual Laser Doppler Flowmetry (LDF) is presented herein to investigate the brain neurochemistry affected by enoxaparin (Lovenox®), an antiplatelet/antithrombotic medication ...
Edwin H. Kolodny, Patricia A. Broderick
doaj   +1 more source

Generation of Pseudo Metabolites as a Side Reaction in On‐Tissue Chemical Derivatization in Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

Chemistry–Methods, Volume 5, Issue 12, November 2025.
On‐tissue chemical derivatization reagents enhance sensitivity and specificity, but the impact of side reactions remains understudied. The reactive matrix FMP‐10 promotes Mukaiyama‐like condensation reactions between endogenous metabolites to form pseudo metabolites that are structurally identical to endogenous metabolites.
Tobias Bausbacher, Alessa L. Henneberg, Stephanie Meyer, Stefan Schmidt, Aubry K. Miller, Christiane A. Opitz, Carsten Hopf   +6 more
wiley   +1 more source