Results 31 to 40 of about 1,611,745 (208)
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters +17 more
wiley +1 more source
From the Chair: Overview [PDF]
Honor Roll! Congratulations to the faculty, staff, residents and fellows here at Jefferson. We have achieved a distinction obtained by less than 0.5% of all American hospitals – this July we were notified that we have joined the U.S.News & World Report ...
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Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Grounding Waste: Towards a Sociology of Waste Networks [PDF]
This article contributes towards building a sociology of waste. It advances a network analysis framework to understand the position and role of the various actors involved in waste governance in Ireland, North and South.
Dr. Honor Fagan
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Why Would Anyone Want to Be a Public Interest Lawyer? [PDF]
I can barely express how grateful the Law Center is to the Delaneys for their generous gift, or what an honor it is to be designated as the first Delaney Family Professor of Public Interest Law at this incredibly vibrant institution. But our celebration
Schrag, Philip G.
core +3 more sources
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
From the Lab to the Stage [PDF]
Biology major Samantha Casale details the honor of singing the national anthem at this year’s Commencement ...
Mulvey, Jenna
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Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Gender Roots: Conceptualizing Honor Killing and Interpretations of Women\u27s Gender in Muslim Society [PDF]
The phenomenon of “honor” killing is one that has formed out of deeply rooted concepts of sexuality and gender roles in Muslim societies. These conceptions have been implemented into everyday life and social infrastructure and have created, in some ...
Barry, Brittany N.
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