Results 51 to 60 of about 164,878 (307)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Câhiliye Arap Toplumunda Kız Çocuklarının Katli Meselesi: İslam Tarihi Perspektifinden Değerlendirme
Cumhuriyet İlahiyat Dergisi, 2019 İslâm gelmeden evvel Arap toplumunda ebeveyn arasında çocuklarına karşı sorumluluk duygusu gayet zayıftı. Ailenin reisi olan erkek, aile bireylerinin tamamını mülkü gibi görüyor ve onlara istediği şekilde davranıyordu.
Ahmet Acarlıoğlu
doaj +1 more source
Honor Moore : A Cook\u27s Life [PDF]
, 2013 The origions of the book came from an autobiography by Honor Edgar she had begun prior to her death in 2013. Honor\u27s eldest daughter Patsy painstakingly compiled this shortened version of what would have been an incredibly long and beautiful journey ...
Moore, Honor
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Honor Moore : Belfast Newsletter Cuttings Scrapbook, 1952 [PDF]
, 1952 Honor Moore wrote a daily cookery column for the Belfast Newsletter from 1944 to about 1968 under the nom de plume Housekeeper . Diary filled with cuttings of Honor Moore\u27s writing as \u27Housekeeper\u27 & hints and recipes deemed useful and ...
Moore, Honor
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
¿Matar al mensajero? La responsabilidad de las redes sociales y los usuarios por difamación
IDPLa Ley Orgánica 1/1982, de 5 de mayo, de protección civil del derecho al honor, a la intimidad personal y familiar y a la propia imagen, dota de recursos jurídicos a las personas perjudicadas por, entre otros supuestos, difamaciones tanto en entornos ...
Laura Herrerías Castro
doaj +1 more source
The honor motive in international relations [PDF]
, 2013 This report aims to broaden the horizon of research questions in international relations by encouraging a greater appreciation for the complexity of individual and collective motivations.
Ofek, Hillel
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Farmacéutico listo, farmacéutico tonto
Farmacéuticos Comunitarios, 2011 Desde su existencia hasta dos generaciones atrás, el farmacéutico era un profesional que se dedicaba a elaborar los medicamentos que el médico prescribía a los pacientes.
Martínez Romero F.
doaj