Results 41 to 50 of about 1,611,745 (208)
Unconventional fermions: The Price of Quark-Lepton Unification at TeV Scales
, 2004 The early petite unification (PUT) of quarks and leptons at TeV scales with sin^2 theta_W(M^2_Z) used as a constraint, necessitates the introduction of extra quarks and leptons with unconventional electric charges (up to 4/3 for the quarks and 2 for the ...
Chacko Z., P. Q. HUNG
core +3 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Leaders of RI State Victim Assistance Academy Receive RI Attorney General Justice Award [PDF]
, 2016 An educational-outreach initiative of Family Service of RI and RWU, leaders from both institutions shared the honor at the 12th Annual Justice ...
Public Affairs, Roger Williams University
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Paper Tigers comes to Boston [PDF]
, 2016 The film "Paper Tigers" came to Boston in honor of Human Rights Day.Boston Public Schools Parent ...
Boston University Howard Thurman Center for Common Ground
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
On Hidden Symmetries in d=11 Supergravity and Beyond [PDF]
, 1999 Invited talk at the conference "Fundamental Interactions: From Symmetries to Black Holes" in honor of Francois Englert, 24 - 27 March, Universite Libre de Bruxelles, BelgiumComment: 14 ...
Nicolai, H.
core +2 more sources