Results 71 to 80 of about 1,600,619 (301)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

«Gente de mal vivir»: familias e hijos rebeldes en Nueva España, 1721-1729

Revista de Indias, 2006
En la Nueva España el traslado forzoso de individuos a las Islas Filipinas y Marianas fue una forma de exilio equivalente a la deportación para castigar a los criminales y a la gente considerada indeseable.
Beatriz Cáceres Menéndez, Robert W Patch   +1 more
doaj   +1 more source

Special vs. Normal Mycenaean: Hand 24 and Writing in the Service of the King? [PDF]

, 1998
This paper given in honor of John T. Killen concerns the relationship between the written and the spoken word within the narrowly defined literate administrative record-keeping systems of Mycenaean palatial centers and focuses on questions connected with
Palaima, Thomas G.
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

RWU President Donald J. Farish to Retire in June 2019, Concluding Transformational 8-Year Tenure [PDF]

, 2018
In recognition of all these achievements, the Board of Trustees has decided to honor President Farish with the title of President Emeritus upon his ...
Public Affairs. Roger Williams University
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Honors [PDF]

Eos, Transactions American Geophysical Union, 2014
John W. Hess has been appointed the new president of the Geological Society of America Foundation beginning in 2015, succeeding Geoff Feiss. Hess is currently the executive director of the Geological Society of America.
openaire   +3 more sources

Some issues of protection of honor, dignity, business reputation and good name

Юридический вестник Самарского университета
The article examines the problems of protecting the honor, dignity, business reputation of citizens, legal entities when disseminating false and defamatory information by posting reviews on the Internet, including both on specialized services for ...
O. V. Moiseeva
doaj   +1 more source

"Weekly Honor Senior Thesis Write-Ins" posters [PDF]

, 2017
This poster aims to make BU students aware of programs available to help them write their Senior Honor Thesis papers with BU Mugar Library.
Richards, Jessica
core