Results 61 to 70 of about 384,646 (364)

Improved gene tree error correction in the presence of horizontal gene transfer [PDF]

, 2014
Motivation: The accurate inference of gene trees is a necessary step in many evolutionary studies. Although the problem of accurate gene tree inference has received considerable attention, most existing methods are only applicable to gene families ...
Bansal, Bapteste, Burleigh, Chen, Choi, David, Delsuc, Doyon, Durand, Eric J. Alm, Felsenstein, Goodman, Guindon, Górecki, Hallett, Harding, Koonin, Lerat, Lerat, Li, Libeskind-Hadas, Liu, Ma, Manolis Kellis, Mukul S. Bansal, Nguyen, Organ, Ovadia, Page, Rambaut, Rasmussen, Rutschmann, Saitou, Salter, Sanderson, Sennblad, Shimodaira, Stamatakis, Stolzer, Storm, Thornton, Tofigh, Tofigh, Vilella, Wapinski, Whelan, Wu, Yang, Yi-Chieh Wu, Yule, Zhaxybayeva, Zhaxybayeva, Åkerborg   +52 more
core   +2 more sources

Metacommunity structure preserves genome diversity in the presence of gene-specific selective sweeps under moderate rates of horizontal gene transfer.

PLoS Computational Biology, 2023
The horizontal transfer of genes is fundamental for the eco-evolutionary dynamics of microbial communities, such as oceanic plankton, soil, and the human microbiome.
Simone Pompei, Edoardo Bella, Joshua S Weitz, Jacopo Grilli, Marco Cosentino Lagomarsino   +4 more
doaj   +1 more source

Detecting Highways of Horizontal Gene Transfer [PDF]

Journal of Computational Biology, 2011
In a horizontal gene transfer (HGT) event, a gene is transferred between two species that do not have an ancestor-descendant relationship. Typically, no more than a few genes are horizontally transferred between any two species. However, several studies identified pairs of species between which many different genes were horizontally transferred. Such a
Bansal, Mukul S., Banay, Guy, Gogarten, J. Peter, Shamir, Ron   +3 more
openaire   +3 more sources

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Role of Horizontal Gene Transfer in Bacteria [PDF]

, 2018
This paper documents an overview on the current knowledge of gene transfer in bacteria with emphasis on the role of horizontal gene transfer, in contrast to the numerous gaps in our understanding of Bacterial gene expression.
Milka, Minase
core   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Adaptive evolution of hybrid bacteria by horizontal gene transfer [PDF]

, 2020
Horizontal gene transfer is an important factor in bacterial evolution that can act across species boundaries. Yet, we know little about rate and genomic targets of cross-lineage gene transfer, and about its effects on the recipient organism's physiology and fitness.
arxiv   +1 more source

Genomic islands: tools of bacterial horizontal gene transfer and evolution [PDF]

, 2008
Bacterial genomes evolve through mutations, rearrangements or horizontal gene transfer. Besides the core genes encoding essential metabolic functions, bacterial genomes also harbour a number of accessory genes acquired by horizontal gene transfer that ...
Buchrieser, Dahlberg, Derek W. Hood, Derrick W. Crook, Frost, Jan Roelof van der Meer, Larbig, Mario Juhas, Muriel Gaillard, Musser, Nguyen, Ravatn, Ravatn, Rosalind M. Harding, Trempy   +14 more
core   +3 more sources

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Horizontal gene transfer in bacteria: an ecological and evolutionary perspective

Acta Agriculturae Slovenica, 2000
In recent years, molecular genetics and genome analysis provided extensive evidence that gene loss and acquisition are likely to be the primary mechanisms by which bacteria genetically adapt to novel or changed environments and by which bacterial ...
Matjaž PETERKA, Tomaž ACCETTO, Gorazd AVGUŠTIN   +2 more
doaj   +1 more source