Results 51 to 60 of about 2,773,225 (337)

Effects of Fracturing Parameters on Fracture Unevenness During Large-Stage Multi-Cluster Fracturing in Horizontal Wells

open access: yesFrontiers in Energy Research, 2021
Horizontal wellswith multi-cluster fracturing technology is an effective approach to exploit unconventional hydrocarbon reservoirs. The on-site diagnosis results indicate that multi-cluster fractures always tend to propagate unevenly due to ...
Rui Yong   +7 more
doaj   +1 more source

The Rattling of Euler's Disk [PDF]

open access: yes, 2006
The motion of a disk spinning on a horizontal surface has drawn a great deal of interest recently. The objectives of the researches are to find out what produces an increasing rattling sound and why the spinning ends so abruptly.
Saje, Miran, Zupan, Dejan
core   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Formulation of New Equation to Estimate Productivity Index of Horizontal Wells

open access: yesIraqi Journal of Chemical and Petroleum Engineering, 2014
Significant advances in horizontal well drilling technology have been made in recent years. The conventional productivity equations for single phase flowing at steady state conditions have been used and solved using Microsoft Excel for various reservoir ...
Ghanim M. Farman, Maha Raouf Abdulamir
doaj  

Identification of different types of kink modes in coronal loops: principles and application to TRACE results [PDF]

open access: yes, 2008
We explore the possible observational signatures of different types of kink modes (horizontal and vertical oscillations in their fundamental mode and second harmonic) that may arise in coronal loops, with the aim of determining how well the individual ...
Andries   +44 more
core   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Well spacing optimization technology for coalbed methane horizontal wells

open access: yesMeitian dizhi yu kantan
BackgroundWell spacing design directly affects the resource utilization and exploitation benefits of blocks. Rational well spacing design plays a significant role in the commercial exploitation of coalbed methane (CBM) fields.
Yuting WANG   +10 more
doaj   +1 more source

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